Basic/Clinical Science Session
Molecular-Driven Management of Lupus Nephritis, One Cell at a Time
October 26, 2024 | 02:00 PM - 04:00 PM
Location: Room 6A, Convention Center
Session Description
Cellular resolved disease modeling is revealing unprecedented insight into lupus nephritis immunopathobiology. Patients can be stratified based on their immune-cell phenotype in kidney biopsy tissue, circulating immune-cell population, and immune mediators. Insights from studies allow linkage of immune-cell phenotypes with treatment responses, moving toward the goal of personalizing treatment choices and targeted treatment trials in lupus nephritis.
Support is provided by an educational grant from Travere Therapeutics, Inc.
Learning Objective(s)
- Summarize immune-cell pathobiology in lupus nephritis
- Define subtypes of lupus in mechanistic molecular terms
- Identify strategies to bring targeted treatments to patients with various lupus subtypes
Learning Pathway(s)
- Glomerular Diseases
- Pathology
Moderators
Presentations
- Catching Lupus Nephritis Molecular Program In Flagranti: Lessons Learned from Accelerating Medicines Partnership Biopsies
02:00 PM - 02:30 PM
- Lupus Nephritis Activity and Treatment Response in Peripheral Blood Lymphocytes: Deep Immune-Cell Profiling
02:30 PM - 03:00 PM
- Urine Proteomics and Liquid Kidney Biopsy in Systemic Lupus Erythematosus
03:00 PM - 03:30 PM
- Developing Targeted Treatments for Lupus Nephritis: Time for Precision Trials
03:30 PM - 04:00 PM