RE: Osteoporosis In Stage 5 Ckd 1 hour ago

The rationale , efficacy and safety issues concerning the use of Rososuzunab or Teriparatide in Adynamic Bone Disease in CJD is very well summarize...

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RE: Osteoporosis In Stage 5 Ckd 5 hours ago

May I ask you what is Rational of using Romosozumib in this patient? How teriparatide modefied dose may help? --------------------------------- Wa...

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RE: Membranous nephropathy 10 hours ago

Hi Dr. Garrick. The duodenal biopsy report came two days ago and it's benign and no dysplastic features. So I hope I can take this as a PLA2R negat...

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RE: Canine amyloidosis treatment options 12 hours ago

Yes! These are my colleagues at the International Veterinary Renal (and Urinary) Pathology Service. It is physically within Texas A&M. Those are th...

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RE: Canine amyloidosis treatment options 18 hours ago

A friend of mine just sent me this poster. It looks like mass spectrometry proteomics is being explored in veterinary medicine. The technique here ...

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RE: Hd Patient Running Out Of Access 19 hours ago

Worth a try considering complexity of the patient certainly as an advanced laparoscopic insertion- to have a nice look around and do adjunctive pro...

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RE: Hd Patient Running Out Of Access 21 hours ago

Thanks prof rodby I had not make That link to perforation and was inquisitive to learn about your thought process.( as in I had not thought about ...

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RE: Canine amyloidosis treatment options 23 hours ago

awwwwwww! ------------------------------ Roger Rodby MD, FASN Professor of Medicine Rush University Nephrology Associates Chicago IL (773) 505-3...

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RE: Hd Patient Running Out Of Access 23 hours ago

well I suppose the anus is attached to the rectum and the rectum to the peritoneal cavity ... Clearly there was a concern of something or you wou...

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RE: Membranous nephropathy 1 day ago

Hi Did results of duodenal return? Perhaps I missed them. Thanks! ------------------------------ Renee Garrick,MD,FACP, FASN Professor of Cl...

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RE: Recurrence of IgA - post transplant 2 days ago

In regards to cost help may be on the way. Recently I did a survey, on a C5 blocker given every 8 weekly ( assuming Ravulizumab). The phase 3 data ...

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RE: decision to stop dialysis in patients who lack capacity and family members have divergent views. 2 days ago

Update - patient admitted to hospital with general deterioration. All Family members agreed to stop and for conservative care Best regards ------...

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RE: Hd Patient Running Out Of Access 2 days ago

What would perforate ? Bw --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------

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RE: Recurrence of IgA - post transplant 2 days ago

I'm curious to see how the felzartamab data stacks up. Also, my understanding is that atacicept has an ongoing trial which specifically includes re...

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RE: Recurrence of IgA - post transplant 2 days ago

With all due respect for the Iptacopan advocates, I think that anti/CD38 MoAB is a better choice for recurrent IgAN in a kidney transplant. Just an...

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RE: Recurrence of IgA - post transplant 2 days ago

Dr. Dastoor This is personal experience since data are lacking A patient with recurrent IgA + MVI (peritubular capillaritis C4d1) that failed ...

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RE: Recurrence of IgA - post transplant 2 days ago

While the clinical trials for iptacopan approval in IgAN did not include any recIgAN post-transplant, there are certainly scattered case reports of...

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RE: Canine amyloidosis treatment options 2 days ago

We don't have HIPAA in veterinary medicine, but the client did give me permission to share photos of PJ! We do see nephrotic edema in dogs and ca...

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RE: Dual Vascultis / Sle 2 days ago

@ prof glassock appreciate your thought on question ? Kind regards --------------------------------- Muhammad Soobadar MBChB UK ----------------...

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RE: GFR measurement in AKI with stable serum creatinine 2 days ago

Thank you Mario. Big Al is offspring 7 of 7 with degrees in engineering, He assisted with confirming the mathematics and graphs. John Pickering i...

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RE: Recurrence of IgA - post transplant 3 days ago

Thanks for your response 1. I agree , we do a tapering dose of steroids , but he is currently taking instructions from his transplant nephrologist...

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RE: Membranous Nephropathy 3 days ago

A measurement of anti-PLA2R antibody by the IFA method would be very helpful. the IFA is more sensitive than the ELISA so a negative result would c...

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RE: Osteoporosis In Stage 5 Ckd 3 days ago

I just responded that I do feel a biopsy is the gold standard, the HR CT scan may be helpfu. I would avoid bisphosphonates in this patient with the...

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RE: Osteoporosis In Stage 5 Ckd 3 days ago

In CKD one cannot use DEXA scans to differentiate osteopenia from Osteoprosus vex CKD-MB. A bone biopsy is the gold standard, A high resolution CT ...

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RE: Osteoporosis In Stage 5 Ckd 3 days ago

Her decreased bone density may not have been the direct result of adynamic bone disease. I do think she would benefit from a biopsy, however, as me...

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RE: Membranous Nephropathy 3 days ago

I no longer use the modified Ponticelli (too much steroids , in my opinion)I rely on Obinutuzumab monotherapy primarily and occasionally use a shor...

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RE: Membranous Nephropathy 3 days ago

Thanks for update . I guess kidney biopsy will tell you . Tissue plar2 , EDD nature features of inflammation on LM or just chronic damage What p...

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RE: Hd Patient Running Out Of Access 3 days ago

I suspect yes, the risk of perforation must be rare but I might as a radiation oncologist. anal cancer is pretty low and I would guess that the PD ...

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RE: GFR measurement in AKI with stable serum creatinine 3 days ago

Congratulations to you and your son(?) Dr. Mellas. Your paper underscores what Dr. Pickering published 14 years ago (see attached) and that most of...

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RE: Osteoporosis In Stage 5 Ckd 3 days ago

Thank you very much for your inputs. Is that reduced bone thickness is solely resultant of adynamic bone disease , the patient refused bone biopsy....

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RE: GFR measurement in AKI with stable serum creatinine 3 days ago

As a follow-up to an old post; Attached is a recently published article describing a modeled mathematical proof of concept that a four hour urine c...

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Hd Patient Running Out Of Access 3 days ago

Can we try pd in patient who has complex vascular and running of vascular access who had radiotherapy for anal squamous cell cancer Thanks

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RE: Dual Vascultis / Sle 3 days ago

And why is crithidia not helpful in this setting? --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------

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RE: Dual Vascultis / Sle 3 days ago

Do you biopsy then? --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------

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RE: Dual Vascultis / Sle 3 days ago

Anca mpo --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------

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RE: Dual Vascultis / Sle 3 days ago

Blood culture negative , echo normal , complement Normal Not on hydralazine . Was dialysis dependent now eGFR 12 ----------------------------...

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RE: Membranous Nephropathy 3 days ago

INR 1/7/2026 2.4 2/18/2026 3.0 3/11/2026 1.6 3/25/2026 2.7 Follows with coumadin clinic and they check every 4 - 6 weeks if INR is stable...

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RE: Dual Vascultis / Sle 3 days ago

Complement (C3, C4) levels, rheumatoid factor, blood cultures, echocardiogram findings? ------------------------------ K.K. Venkat MD Troy MI (24...

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RE: Dual Vascultis / Sle 3 days ago

Was the ANCA an anti-MPO or anti-PR3 or both? ------------------------------ Richard Glassock MD, FASN Laguna Woods CA (949) 388-8885 -----------...

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RE: Dual Vascultis / Sle 3 days ago

I don't think a Crithidia based antidsDNA will make much difference in therapy, regardless if the result.. Avacopan not indicated in dialysis depen...

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Dual Vascultis / Sle 3 days ago

82 female , good functional status , hx of weight loss and unresolving chest infection/cough and haemoptysis needing filter and High flow 02 in Cal...

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RE: Recurrence of IgA - post transplant 3 days ago

Dr. Dastoor/ as you know the optimal therapy for recurrent IgAN in a kidney transplant is highly uncertain due to the absence of any trials- a cour...

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RE: complex case of nephrotic syndrome in liver transplant patients 3 days ago

Thanks prof glassock really helpful Kind regards --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------

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Recurrence of IgA - post transplant 3 days ago

Have a 60 year old gentleman , who underwent a living unrelated kidney transplant in the Phillipines approximately 8 years ago. Etiology of his r...

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RE: FSGS vs C3G and Canavan Disease 3 days ago

She has been steroid on pulse steroids and MMF for now Awaiting EM results Creatinine slightly elevated last 24 hours ( ??Trimethoprim contri...

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RE: Polyuria 3 days ago

Thanks Jaison. Better to do a cystoscopy then to rule out a chronic cystitis. In which case she will need further evaluation of the bladder with ur...

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RE: Dialyzer reaction 3 days ago

Good morning Dr. Shah. Thank you for sharing your experience. Nipro Cellentia sounds like a strong backup option for patients with dialyzer reactio...

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RE: Dialyzer reaction 3 days ago

Before dialysis, BUN was 79, serum sodium was 137. Thank you so much for your input! ------------------------------ Jinwook Park MD Assistant Pro...

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RE: Polyuria 3 days ago

I think, as Dr Rodby has noted, the lack of nocturia makes this more a 'habit' issue than a pathology. If there were a concentration defect, she wo...

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RE: Osteoporosis In Stage 5 Ckd 3 days ago

Thanks Dr. Sprague - after a deeper read and consultation with Open Evidence i agree with you concerning the lack of evidence demonstrating a clear...

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