RE: SLE and HUS 1 hour ago

Thank you, Dr. Venkat. The APL screen was negative. Regarding the initial positive ANA at the time of presentation in 2015, the results were ...

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RE: Transplant Case- can recurrent Ig A in transplant patient present without proteinuria and midly low C3 and more significant lower C4. 1 hour ago

Dear Dr. Muhamad, Is there any evidence of microscopic hematuria? Recurrence of IgA nephropathy is still possible even in the absence of prote...

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RE: SLE and HUS 1 hour ago

Anti-phospholipid antibody screen results? Did she ever manifest hematological features of TMA/HUS, or was it only renal-limited TMA? What were the...

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RE: Debating taking boards, what rec's would you have for study materials/Courses? 2 hours ago

l I intentionally posted here bc this community is so active and lol'ed bc the responses are from those who were/are involved in writing questions....

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RE: Debating taking boards, what rec's would you have for study materials/Courses? 2 hours ago

NephJC is so awesome, their podcast is great too. I'll check out KSAP ------------------------------ Nimra Sarfaraz, DO (516) 637-3820 nimras@gm...

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RE: Debating taking boards, what rec's would you have for study materials/Courses? 2 hours ago

thanks so much, those flash cards are great and the Q banks that came with the course too. I will check out renal fellow network Would you hvae a...

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RE: Transplant Case- can recurrent Ig A in transplant patient present without proteinuria and midly low C3 and more significant lower C4. 4 hours ago

Was EM done or available on biopsies? Absence of proteinuria calls into question though does not completely exclude recurrent IGAN or Lupus or othe...

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Doac Use In pD 8 hours ago

Hi any colleagues have opinion in Doac and use in PD Bw

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RE: Dual Vascultis / Sle 8 hours ago

We tend to use 2 pulse cyclo for Anca Vascultis combined with ritux but have avoided cyclo as pt is elderly many thanks -------------------------...

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SLE and HUS 12 hours ago

Dear all I would like to discuss an interesting case and share an expert opinion regarding the long-term management plan for a 29-year-old Oman...

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RE: Membranous Nephropathy Clinical Case 13 hours ago

This patient with PLA2R Primary MN is in complete immunological remission induced by by RTX- no further IS , including CNI is indicated. The residu...

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RE: Fibronectin glomerulopath 14 hours ago

In my opinion the EM findings are quite compatible with Finronectin glomerulopathy and exclude "idiopathic nodular glomerulosclerosis" If you think...

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RE: Transplant Case- can recurrent Ig A in transplant patient present without proteinuria and midly low C3 and more significant lower C4. 14 hours ago

I agree with Dr. Venkat - the immunoperoxidase studies and the low C4/C4 call into question the. Diagnosis of "recurrent IgAN". What are the eGFR a...

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RE: Debating taking boards, what rec's would you have for study materials/Courses? 16 hours ago

So since we are being transparent about our COI's, my suggestion to use BRCU practice questions and the Pearls and the Flash cards (I was co-Driect...

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RE: Membranous Nephropathy Clinical Case 16 hours ago

Thanks for your comments. The patient received more than 30 gr of Cyclophosphamide without response. At some point tends to respond to Cyclosp...

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RE: dealing with CRS in ATG use as induction or treatment of ABMR 17 hours ago

"First Biopsy 23/12/25 2nd Biopsy attached 02/05/26" Dr. Soobadar: Can you please post serum creatinine trends between the first and second biops...

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RE: Transplant Case- can recurrent Ig A in transplant patient present without proteinuria and midly low C3 and more significant lower C4. 17 hours ago

"Immunoperoxidase studies show glomerular staining for IgA, IgG, IgM, C3 and C1q." This sounds like "full house" pattern. Lupus serology especial...

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RE: Transplant Case- can recurrent Ig A in transplant patient present without proteinuria and midly low C3 and more significant lower C4. 21 hours ago

Immunoperoxidase studies show glomerular staining for IgA, IgG, IgM, C3 and C1q. Results-Comments In the clinical context of this case (?? ESRF s...

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RE: Transplant Case- can recurrent Ig A in transplant patient present without proteinuria and midly low C3 and more significant lower C4. 21 hours ago

Specimen Type: Renal transplant biopsy Clinical Details: Directly entered by electronic request:47 year old with Live donor transplant from mothe...

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Transplant Case- can recurrent Ig A in transplant patient present without proteinuria and midly low C3 and more significant lower C4. 21 hours ago

46 F Live related kidney transplantation from mother January 2009 - CKD stage 3 with slowly deteriorating function Transplant kidney biopsy - mild...

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RE: dealing with CRS in ATG use as induction or treatment of ABMR 22 hours ago

First Biopsy 23/12/25 2nd Biopsy attached 02/05/26 irectly entered by electronic request: ESRF unclear cause.DBD transplant Nov 25. Biopsy Dec 2...

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RE: dealing with CRS in ATG use as induction or treatment of ABMR 22 hours ago

Clinical Details: Directly entered by electronic request:DBD Tx 7/11/25. ESRD - unknown cause, FMD B/L. Function peaked at eGFR 41, now declining w...

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RE: dealing with CRS in ATG use as induction or treatment of ABMR 22 hours ago

23/12/25-Post transplant sample. HLA-A*02:01 (MFI = 5767), A*24:01 (MFI = 11015), B39 (MFI = 13886), B*40:01 (MFI = 10187), C*03:04 (MFI = 1168), D...

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RE: dealing with CRS in ATG use as induction or treatment of ABMR 22 hours ago

30 MDBD transplant November 2025 (2:2:1 mismatch, CMV D+/R-) Transplant dysfunction and biopsy in Dec 25 showing ATN only with no evidence of ABMR...

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RE: Dual Vascultis / Sle 22 hours ago

many thanks prof rodby and colleagues pt had 2 rituximab and methlypred followed by oral and avacopan( this was discussed with her in view of new...

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RE: Membranous Nephropathy Clinical Case 1 day ago

Try change statin as rosuvastatin can cause some proteinuria ------------------------------ Radu Raducu MD MD Sanford Hospital BIsmarck ND (203) ...

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RE: Membranous Nephropathy Clinical Case 1 day ago

I would rebiopsy to see the cause of increasing serum creatinine despite complete immunological remission. I don’t know why you use a combination ...

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RE: Debating taking boards, what rec's would you have for study materials/Courses? 1 day ago

I guess I have a bit of a conflict of interest because I now write KSAP questions (though I've contributed like 2 or 3 or so far). But, thinking ba...

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RE: A Case of Extreme Persistent Polyuria After Obstructive Uropathy 1 day ago

"Fluid replacement was started according to standard practice, initially matching urine output volume-for-volume and later reduced to approximately...

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RE: Membranous Nephropathy Clinical Case 1 day ago

Given the inter - individual variability of uPCR I would not interpret the last change as significant. seems like immunological remission has take...

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RE: Fibronectin glomerulopath 2 days ago

EM reports non conclusive - Focal effacement of foot processes of visceral epithelial cells is noted (about 35-40%). Mesangial matrix appears mar...

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RE: A Case of Extreme Persistent Polyuria After Obstructive Uropathy 2 days ago

This appears to be a mixed diuresis, but it is predominantly solute-driven at this stage, largely fueled by the ongoing intravenous fluid replaceme...

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RE: A Case of Extreme Persistent Polyuria After Obstructive Uropathy 2 days ago

Most of the time this is due to 'chasing' the urine output. I note that you have reduced the replacement fluid to 70 percent but I believe that is ...

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Membranous Nephropathy Clinical Case 2 days ago

Hello, I want to share with you this case. 54yo male, dyslipidemia, coronary artery disease with Angioplasty-Stent 2019, FE 73%. Diagnosed MN...

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A Case of Extreme Persistent Polyuria After Obstructive Uropathy 2 days ago

I have two patients with a very similar clinical presentation. The first is a 55-year-old male with chronic obstructive uropathy secondary to ben...

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RE: Debating taking boards, what rec's would you have for study materials/Courses? 2 days ago

If you took the ASN's board review course you should have a data bank of > 500 practice questions, hundreds of "Pearls" and hundreds of Flash cards...

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Debating taking boards, what rec's would you have for study materials/Courses? 2 days ago

Hi all! I'm debating taking the boards and unenrolling from LKA, what recomendations would you have in terms of study materials? I've taken the A...

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RE: Dual Vascultis / Sle 3 days ago

What about the anti-GBM titer? The biopsy will confirm the diagnosis and guide treatment in this old-age patient with low GFR ----------...

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RE: Dual Vascultis / Sle 3 days ago

Double positive ANCA ANA is not that unusual, ANCA in the presence of lupus worsens prognosis a bit but I dont care what you call this. It total...

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RE: Dual Vascultis / Sle Thursday, June 4 @ 11:08 AM

Thanks prof glassock --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------

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RE: Dual Vascultis / Sle Wednesday, June 3 @ 7:31 PM

This means that the ELISA was probably a false + ------------------------------ Richard Glassock MD, FASN Emeritus Professor Geffen School of Med...

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RE: Dual Vascultis / Sle Wednesday, June 3 @ 6:20 PM

@ prof glassock ? --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------

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RE: Intersting case-Need your opinion Wednesday, June 3 @ 5:40 PM

Thanks for case I have sent uk checklist for ahus How long would complement antibodies and complement genertiv test take From what prof glassock ...

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RE: Intersting case-Need your opinion Wednesday, June 3 @ 5:31 PM

https://www.atypicalhus.co.uk/wp-content/uploads/2023/04/National-aHUS-Service_diagnostic-checklist-v11.04.2023.docx -----------------------------...

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RE: hemodialysis ascites Wednesday, June 3 @ 5:24 PM

Thanks Dr Glassock; I value your analysis more than AI-Claude. However I don't think your AI knows the difference between "a definition" and "a dis...

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RE: hemodialysis ascites Wednesday, June 3 @ 10:08 AM

This indicate different serosal environment and different cells residence. Pericardial tissue has sparse cells and the pericarditis in uremia is du...

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RE: hemodialysis ascites Wednesday, June 3 @ 9:36 AM

uremic pericarditis can have a predominance of neutrophils. why would a uremic peritonits be different? --------------------------------- J Gunne...

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RE: Help me make sense of this 24 hr urine study for stones. Wednesday, June 3 @ 9:17 AM

Hi Dr Anand, I think that is a very good question. I believe the difference is that citrate is trivalent and has two carboxyl groups with much...

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RE: hemodialysis ascites Wednesday, June 3 @ 9:11 AM

Resolution of ascites with increasing UF plus water and salt restriction is both diagnostic and therapeutic for nephrogenic ascites. I tend to dis...

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RE: hemodialysis ascites Wednesday, June 3 @ 8:41 AM

His serum albumin 3.1. His fluid LDH 242, glucose 114. Cytology x2 neg on the fluid though this is low sensitivity. EGD AND Colonoscopy neg. I have...

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