RE: AKI - 3 weeks post normal vaginal delivery 7 minutes ago

Thank you Dr. Glassock! Renal biopsy done. Renal function worsening. ------------------------------ T. Kaur, MD FACP Nephrologist/HTN/Kidney Sto...

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RE: Non-necrotizing granulomatous interstitial nephritis 1 hour ago

I shall. I agree with you. Hematopathology has become an integral part of onco-nephrology. For educational purposes, I was underscoring the phenoty...

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RE: Non-necrotizing granulomatous interstitial nephritis 1 hour ago

Thank you! Please let me know of any typos so I can correct them for the final version! 😀 Regarding CLL diagnosis, we should consult with hemato...

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RE: Non-necrotizing granulomatous interstitial nephritis 2 hours ago

Got your paper Lynn. Now, I have a lovely weekend reading material! KUDOS! I guess, looking for CD5 expression will aid in the diagnosis of CLL. Ma...

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RE: transplant recurrent FSGS 2 hours ago

Thank you Dr. Cravedi. Very helpful information. I guess the final chapter remains to be written. Best. Mario ------------------------------ M...

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RE: transplant recurrent FSGS 2 hours ago

Thank you, Dr. Rubin, for the kind words. Yes, together with Dr. Angeletti in Genoa, Italy, we have accumulated some experience with this approach...

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RE: Non-necrotizing granulomatous interstitial nephritis 2 hours ago

Thank you, Jonathan! I still have to correct the proofs... but the final version when available is supposed to be open access too so everyone can...

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RE: Non-necrotizing granulomatous interstitial nephritis 3 hours ago

Also good time to highlight Dr. Cornell's tour de force review on all things tubulointerstitial forthcoming in KI: https://www.kidney-international...

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RE: Non-necrotizing granulomatous interstitial nephritis 3 hours ago

Came here to point out the same thing- although unlikely, you don't want to miss CLL as a cause of granulomatous interstitial nephritis. The CLL ca...

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RE: transplant recurrent FSGS 3 hours ago

Thank you for sharing this interesting paper. The authors make several key points but 2 of them called my attention: 1. Circulating levels of ant...

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RE: transplant recurrent FSGS 3 hours ago

There is a very elegant study by Angiletti and Cravedi exploring the hypothesis that autoreactive IgM plays a pathogenic role in nephrotic syndrome...

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RE: transplant recurrent FSGS 4 hours ago

@Paolo Cravedi Paolo Cravedi (a superb immunologist) is, most likely behind this idea of combining anti B cell- Plasma cell therapy and I am wond...

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RE: Non-necrotizing granulomatous interstitial nephritis 4 hours ago

About 20-30% of patients with Sarcoidosis present in a renal limited fashion- so this case is somewhat atypical but by no means rare. Early steroid...

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RE: Non-necrotizing granulomatous interstitial nephritis 4 hours ago

Thank you all for the invaluable insights and guidance on this case. To update the panel, the patient's ANA 23-profile (including anti-SSA and ant...

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RE: Non-necrotizing granulomatous interstitial nephritis 4 hours ago

Assuming that the patient is not taking any drugs known to produce granulomatous interstitial nephritis, my AI consults - (Expert AI (UpToDate ) an...

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RE: Tumoral calcinosis in a PD patient 5 hours ago

Tumoral calcinosis is poorly understood, but as this is progressive I would treat this as calciphylaxis with HD, sodium thiosulfate (STS) avoid Ca ...

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RE: transplant recurrent FSGS 5 hours ago

I have attached the article referred to by Dr Venturelli I find it interesting that they would use BOTH anti-CD 20 and anti-CD 38 since anti CD 3...

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RE: Non-necrotizing granulomatous interstitial nephritis 5 hours ago

I agree with everyone and everything above, and Dr Glassock's additional suggested work-up, and yet when you are done you will start steroids for S...

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RE: transplant recurrent FSGS 5 hours ago

Dr. Hirsch I cannot say anything about pre transplant treatment and I acknowledge but working with our pediatric colleagues we have seen responses ...

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RE: Radioiodine treatment in Patient with CKD stage 4 5 hours ago

https://community.asn-online.org/communities/community-home/digestviewer/viewthread?MessageKey=b916ea5e-55bd-49cf-a2d4-0ba62a9d1e3e&CommunityKey=a6...

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RE: Non-necrotizing granulomatous interstitial nephritis 6 hours ago

Other rare ddx for GIN also include inflammatory bowel disease, BCG therapy, the CLL. ------------------------------ Jonathan Zuckerman MD, PhD ...

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RE: Non-necrotizing granulomatous interstitial nephritis 6 hours ago

Dr. Duong this is probably a very obvious point but consider that in TINU uveitis can occur several months after interstitial nephritis --------...

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RE: Non-necrotizing granulomatous interstitial nephritis 6 hours ago

Interesting question. I am not aware of any studies have evaluated such findings to that degree of granularity (if anyone know any, please share). ...

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Tumoral calcinosis in a PD patient 6 hours ago

I have this 47 TO male patient with ESRD due to DM, HTN, PVD, high phosphorous in past who developed painful gluteal masses and imaging and finally...

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RE: Non-necrotizing granulomatous interstitial nephritis 7 hours ago

Dr. Zuckerman - Dr. Zuckerman -thanks for your review and interpretation of the digital renal pathology in this case. How do you define "exube...

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RE: transplant recurrent FSGS 7 hours ago

Thank you for sharing this interesting case. This is a presentation that we not uncommonly encounter in kidney transplantation. At our center,...

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RE: Non-necrotizing granulomatous interstitial nephritis 7 hours ago

The granuloma formation in this case is exuberant. While the most common etiology for GIN is drug/allergic TIN, would definitely consider sarcoidos...

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RE: AKI - 3 weeks post normal vaginal delivery 7 hours ago

Tragic case. The Findings suggest the uncommon occurrence of incomplete or partial bilateral renal cortical necrosis ,following a "normal vaginal d...

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RE: Non-necrotizing granulomatous interstitial nephritis 8 hours ago

Thanks you for your full description of this Challenging case . Given the clinical and pathological fibdibgs, I doubt this is renal /pulmonary myco...

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Non-necrotizing granulomatous interstitial nephritis 16 hours ago

Dear colleagues, I'd like to share a diagnostically challenging case from our nephrology unit, on which I would value the community's input. Pati...

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RE: Post Partum AKI 17 hours ago

Last creatinine os 4.6 frm 2.8, p/c of 17, blood pressure of 130/92 Her Bicarbonate is 17 Phosphate 6 Calcium 7.5. I pulsed her, treated her and pl...

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AKI - 3 weeks post normal vaginal delivery 20 hours ago

Hello All, I have a 31 y/o'clock female, h/o Caroli's disease s/p Liver Transplant 2010, currently on Tacrolimus (trough goal about 3), had a no...

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RE: MPGN with negative IMF 21 hours ago

I think the EM findings likely make Fibrillary GN an untenable diagnosis, unless the images were not examined at high magnification. Could you plea...

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RE: Radioiodine treatment in Patient with CKD stage 4 22 hours ago

zahmad@kidneycareok.com thank you ------------------------------ Zubair Ahmad MD Tulsa OK (585) 329-9640 ------------------------------

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RE: transplant recurrent FSGS 1 day ago

@Sheldon Hirsch I do not have the answer to your excellent points. Clearly, there is a permeability factor(s) in the sera of patients with recurr...

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RE: transplant recurrent FSGS 1 day ago

Related...in the reference provided, 40% of patients with neg anti-nephrin Ab still lost their allograft function by six months. Perhaps there is m...

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RE: transplant recurrent FSGS 1 day ago

Excellent question. I do not have the "answer". As you know, the permeability factor story has changed overtime: the Sabin factor, SUPAR and now an...

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RE: transplant recurrent FSGS 1 day ago

@Mario Rubin, Do you think that anti-nephrin antibodies is the elusive permeability factor or may there be more to the story, I ask because you w...

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RE: Radioiodine treatment in Patient with CKD stage 4 1 day ago

We have a special protocol, can share if u email me, using official email.. private domains blocked --------------------------------- Dr. Hormaz ...

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Radioiodine treatment in Patient with CKD stage 4 1 day ago

I have a 66-year-old male with diabetic nephropathy with CKD stage IV, creatinine of 3.1 and a GFR of 21 mL/min as of May 2026,, CLL, coronary arte...

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RE: transplant recurrent FSGS 1 day ago

@Astrid Weins @Ibrahim Batal As already stated, this is a very difficult problem but, nowadays, we have an objective tool to assess the possibi...

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RE: transplant recurrent FSGS 1 day ago

Wow, I had a patient who lost 2 transplant to recurrent disease then on the third with aggressive pheresis was able to keep it, and was eventually ...

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transplant recurrent FSGS 1 day ago

I have a 37 year old man with ESRD. He presented ~ 2020 with new onset nephrosis, FSGS on biopsy, and progressed to ESRD within one year. He receiv...

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RE: High output HF from AVF? 1 day ago

No, no tortuous or large. And always, "eye test" is important. Thank you. ------------------------------ Esra Ekiz, MD Nephrology Attending Ph...

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RE: High output HF from AVF? 1 day ago

AVF occlusion test was done with no improvement in BP, so yes, I too said the same but the question came from ICU as hypotension was not able to be...

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RE: High output HF from AVF? 1 day ago

Volume overload improved to some extent, though there is still room to go. Our fistula surveillance studies are reported as proximal-mid-distal b...

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RE: MPGN with negative IMF 1 day ago

Few cases with fibrillary GN without igg have been described( very rare) consider DNAJB9. Long shot May be pathologist can comment -------------...

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RE: Post Partum AKI 1 day ago

I don't doubt the renal disease but the high proteinuria of 13 g you mentioned above. My next step would be the biopsy. Here I get results within o...

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RE: MPGN with negative IMF 1 day ago

Is BP well controlled? TMA in the setting of uncontrolled hypertension can cause an MPGN-pattern of injury. ------------------------------ K.K. V...

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RE: MPGN with negative IMF 1 day ago

Would you be able to post the anonymized pathology report and/or images from the case. Main ddx of MPGN pattern without deposits would be chronic...

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