Reminder: Encourage fellows to volunteer as case report reviewers for Kidney Week 2026! 31 minutes ago

ASN invites ASN Fellows-in-Training members to serve as reviewers for case reports submitted by trainees for Kidney Week 2026. The reviewing/gradin...

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Reminder: Volunteer by April 29 to serve as a case report reviewer for Kidney Week 2026! 31 minutes ago

ASN invites ASN Fellows-in-Training members to serve as reviewers for case reports submitted by trainees for Kidney Week 2026. The reviewing/gradin...

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RE: Pd Question 3 hours ago

HAve seen a couple; Pulmonary folks did not want anything lifting diaphracm, plus fear of peritoneo-pleural leaks so catheter and hemo plus drain a...

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RE: complex case of nephrotic syndrome in liver transplant patients 3 hours ago

How long did you observe the patient without therapy after stopping Sirolimus? This is crucial information lacking in your presentation ---------...

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RE: Pd Question 5 hours ago

There are a lot of theories as to why intensivists are so opposed to PD, especially because there is no evidence for this. Probably much of this is...

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RE: complex case of nephrotic syndrome in liver transplant patients 8 hours ago

Rituxan seemed to have done the trick . --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------

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RE: complex case of nephrotic syndrome in liver transplant patients 8 hours ago

Hi prof glassock thanks for reply Sirolimus was stopped and despite that nephrotic syndrome did not resolve. Steroids was tried and did not impro...

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RE: complex case of nephrotic syndrome in liver transplant patients 12 hours ago

This case seems to be an example of Sirolimus induced podocytopathy with spontaneous resolution upon stopping the agent. I know of no evidence for ...

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RE: Gross Hematuria 14 hours ago

Sorry for my late entry into the dialogue generated by this case. The fact that she is a habitual distance runner raises the possibility of exercis...

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RE: Pd Question 21 hours ago

@ prof bargman Would appreciate your thoughts on this. For PD patient who get acutely unwell and needing intubation ventilation not for pd peritoni...

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RE: decision to stop dialysis in patients who lack capacity and family members have divergent views. 22 hours ago

thanks everyone. family had sought IMCA but they said they don't have anything to offer. patient admitted with general deterioration and all ...

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complex case of nephrotic syndrome in liver transplant patients 22 hours ago

22 female complex patient with liver transplant due to Auto immune hepatitis developed nephrotic syndrome while on Sirolimus. Liver transplant team...

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RE: Gross Hematuria 1 day ago

I think I would ask her to stop running for a few weeks! Also are the urine RBCs acanthcytic If that is a word) at all? Does she have albumin...

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RE: Gross Hematuria 1 day ago

Hi Michael, this is a longshot, but if the patient is African-American would get a hemoglobin electrophoresis to rule out sickle cell trait, which ...

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RE: Membranous nephropathy 1 day ago

Thank you for the clarification. For those interested, these are the references which support Dr. Glassock's statement: Sethi et al., Kidne...

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RE: Membranous nephropathy 1 day ago

That is mostly due to NELL1 which was negative in this case. ------------------------------ Richard Glassock MD, FASN Laguna Woods CA (949) 388-8...

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RE: Membranous nephropathy 1 day ago

I was under the impression that, although not a single IgG subclass is reliably specific, IgG1 and IgG2 are the most common isotypes identified in ...

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RE: Membranous nephropathy 1 day ago

Thanks Vito

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RE: Gross Hematuria 1 day ago

Any clots in the urine? ------------------------------ K.K. Venkat MD Troy MI (248) 420 7798 ------------------------------

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RE: Gross Hematuria 1 day ago

Its all "nuts" to me! ------------------------------ Michael Emmett MD Chief of Internal Medicine Emeritus Baylor University Medical Center Dalla...

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RE: Gross Hematuria 1 day ago

Wops - I meant nutcracker syndrome not nutmeg syndrome. Sorry for the typo. ME ------------------------------ Michael Emmett MD Chief of Intern...

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RE: Gross Hematuria 1 day ago

Is this gross hematuria or pigmenturia (Hb, Mb)? Was this documented by a careful examination of the urine sediment? I thought that the Nutmeg Synd...

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Gross Hematuria 1 day ago

An internist colleague, David Cohen at Lankenau Hospital in Philadelphia, has asked me to consider the following case and we both would appreciate ...

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RE: IgAN and pregnancy 2 days ago

that was a nice response to steroids and there is evidence that steroids do have a few years of memory , see attached abstract from Kidney wee...

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RE: Membranous nephropathy 2 days ago

Since the biopsy was negative for PLA2R and NELL 1 I doubt that staining for IgG subclass is going to help with treatment decision making. There is...

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RE: Membranous nephropathy 2 days ago

Thanks Dr. Campese for your opinion. Congo red was negative. IgG was positive (3+), subtyping of IgG was not done. ----------------------------...

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RE: IgAN and pregnancy 2 days ago

How much steroids have been given? I would probably continue her RAASi till pregnancy is confirmed just as Dr Glassock has said but I would also pe...

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RE: Sarcoid assoc Ca stones 2 days ago

Vit d 1,25 55 pth 45 Ca 10.1 ------------------------------ Jonathan Slater MD Renal & Transplant Associates of New England Longmeadow MA ...

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RE: IgAN and pregnancy 2 days ago

Thanks for the additional information. The course if steroids was definitely indicated snd her course so far has been satisfactory/ of course, she ...

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RE: IgAN and pregnancy 2 days ago

She is 36 years in age and not a diabetic. Her BMI is 18.5kg/m2 and her baseline blood pressure is 100-120/60s mmHg. Pre treatment hematuria was 7 ...

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RE: IgAN and pregnancy 2 days ago

Diffucult problem. Before opining -i need to know her BMI , diabetes status, Oxford MEST-C score, hematuria severity, Blood pressure and eGFR trend...

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IgAN and pregnancy 2 days ago

Dear seniors, I wish to draw on your experience in the management of IgAN in pregnant ladies. My lovely patient was diagnosed with biopsy prove...

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RE: Sarcoid assoc Ca stones 2 days ago

As @John Asplin said "Both what have been referred to as absorptive and renal leak hypercalciuria are treated with thiazides." Part of the point th...

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RE: Membranous nephropathy 2 days ago

Thanks Dr. Garrick for your advice. The duodenal biopsy report is pending. I shall post it as soon as it's available. --------------------------...

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RE: Membranous nephropathy 2 days ago

Understood Thanks Dr. Rodby. ------------------------------ Emilio Venturelli MD Scuola di specializzazione in Nefrologia, Università degli st...

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RE: Membranous nephropathy 2 days ago

The original post had the path, but it was not deidentifed enough so we had that part removed. For what it is worth, I was convinced it was MGN. ...

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RE: Membranous nephropathy 3 days ago

Thanks Dr. Glassock for your advice. ------------------------------ Jaison George MD, MBBS Kollam, India ------------------------------

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RE: Membranous nephropathy 3 days ago

Thanks Dr. Rodby for your advice. ------------------------------ Jaison George MD, MBBS Kollam, India ------------------------------

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RE: Membranous nephropathy 3 days ago

Dr. George, I'm not sure that the information you provided are enough to classify this patient has having membranous nephropathy, can you post a mo...

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RE: Membranous nephropathy 3 days ago

CA 125 is a poor marker of cancer in MN. It can be positive due to hypoalbuminemia, edema, serositis, inflammation. A negative test does not rule o...

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RE: Membranous nephropathy 3 days ago

Hi Do you have the biopsy results back from the duodenal lesion?Thinking about possibility of mantle cell lymphoma of the duodenum, which can lea...

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RE: A 19-Year-Old Male with Frank Hematuria, Proteinuria, and Weak Anti-GBM Positivity 3 days ago

any update on the Renal Bx findings ? ------------------------------ Dr Mohamed Buhary MBBS, CCT, FRCP Consultant Nephrologist Jeddah --------...

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RE: Sarcoid assoc Ca stones Sunday, April 12 @ 2:07 PM

Dr. Slater - can you also let us know what the repeat 1,25 dihydroxy Vitamin D level showed.? ------------------------------ Richard Glassock MD,...

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RE: Membranous nephropathy Sunday, April 12 @ 1:45 PM

Steroids alone are ineffective in Primary MN, with or without antiPLA2 R antibody. The utility of serum Biomarkers ( such as CEA or CA125) for canc...

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RE: Membranous nephropathy Sunday, April 12 @ 1:05 PM

The cancer scanning was negative despite high CA125 level, I don't know how specific that level is for an occult malignancy, nor do I know if a PET...

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Membranous nephropathy Sunday, April 12 @ 12:59 PM

Requesting guidance regarding a case of a frail 72 year old lady with a history of type 2 diabetes mellitus and systemic hypertension since 2016, a...

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RE: decision to stop dialysis in patients who lack capacity and family members have divergent views. Sunday, April 12 @ 8:43 AM

Dr Venkat is spot on with the legal position, but who is actually going to go through with the "fight"? This is a problem in the US, especially in ...

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RE: Sarcoid assoc Ca stones Sunday, April 12 @ 8:35 AM

Thanks for the extra information. I agree that a 60 yo man with a creat/kg of 27 is likely an overcollection. Sorry I wasn't clear, when I referr...

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RE: Sarcoid assoc Ca stones Sunday, April 12 @ 6:17 AM

Thx for input PT is male and weighs 60 kg so perhaps not a signif overcollection and even so he has hypercalcuia even if 10-20% overcollection; al...

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RE: decision to stop dialysis in patients who lack capacity and family members have divergent views. Saturday, April 11 @ 5:59 PM

From a US legal perspective (do not know if this will apply in the UK), I got the following from Google AI: "Court decisions generally support doc...

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