RE: Membranous Nephropathy 6 hours ago

A CNI will not help ( much) for inducing a lasting immunological remission.- I do not recommend this option. ------------------------------ Richa...

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RE: Post Partum AKI 6 hours ago

But was it looked for? Is this the first pregnancy or one of multiple. If multiple, , any toxemia events or proteinuria with prior pregnanies.? -...

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RE: Post Partum AKI 7 hours ago

No proteinuria reported in the 1st trimester. --------------------------------- Wael Jebur MD drwaellatif@hotmail.com Dubai ---------------------...

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RE: Membranous Nephropathy 7 hours ago

Consider combining a CNI with antiCD 20 inhibitors . The combination seems to work very well. Risk of recurrence is high when you with hold CNI tho...

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High output HF from AVF? 8 hours ago

Dear community, Here is a 69 y/o gentleman w ESRD (presumed to be 2/2 FSGS + post nephrectomy for RCC) on HD via R BC AVF since 2022, w asx CAD, ...

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RE: Membranous Nephropathy 8 hours ago

You could try a short 8 week course of CYC ( 1-1.5mg/kg po) to see if you can prolong the B-cell reducing effect of OBI and yield am more prolonged...

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RE: low phosphate and smoldering myeloma 10 hours ago

Thank you for your prompt answer. Back in February his ratio was 17. So he is edging on the myeloma stage. ------------------------------ Mario ...

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RE: low phosphate and smoldering myeloma 10 hours ago

Dr. Rubin: A FLC ratio > 8 is a risk factor for high risk MGUS. A ratio > 20 is a risk factor for smoldering myeloma for progression to multiple ...

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RE: Membranous Nephropathy 10 hours ago

Update: ANCA Negative C3, C4 normal DS DNA Negative ------------------------------ Sachin ------------------------------

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RE: low phosphate and smoldering myeloma 10 hours ago

@Nelson Leung Is a huge Kappa/Lambda ratio (as in this case) enough to label this patient as suffering from a high risk smoldering myeloma? As su...

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RE: low phosphate and smoldering myeloma 11 hours ago

The data is compelling to treat the MM. The 24h urine phosphate is actually on the low end. If the patient intake is sufficient, intestinal wasting...

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RE: Membranous Nephropathy treatment 12 hours ago

Elisa is also available. ------------------------------ James Wells MD Atlanta GA (770) 934-2585 ------------------------------

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RE: yeast peritonitis and return to PD. 13 hours ago

Thanks really helpful --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------

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RE: Membranous Nephropathy treatment 14 hours ago

And I you have Elisa you can do repeated measurement and check treatment response . IFA is not used for monitoring ( under correction of prof gla...

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RE: Membranous Nephropathy treatment 14 hours ago

Thank you ------------------------------ James Wells MD Atlanta GA (770) 934-2585 ------------------------------

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RE: Membranous Nephropathy treatment 14 hours ago

1:100 means you are using the IFA rather than ELISA . The ELISA is preferred as it is quantitative (RU/ml). But this is a clearly positive result i...

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RE: yeast peritonitis and return to PD. 15 hours ago

One lady came back to PD and got another yeast peritonitis for which I felt terribly! She had the second catheter removed and stayed on hemo. Inter...

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RE: Membranous Nephropathy treatment 15 hours ago

Is 1:100 considered a high or low titer? ------------------------------ James Wells MD Atlanta GA (770) 934-2585 ------------------------------

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RE: Membranous Nephropathy treatment 15 hours ago

It is the only titer I have. Proteinuria responds to change in CSA dosage. Now 460 which seems very good. Just concerned about the rise in creatini...

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RE: AI Transparency in Kidney Week Abstract Submissions 15 hours ago

Thank you for the clarification! ------------------------------ Karin Bergling MD, PhD Senior Clinical AI Scientist Renal Research Institute New ...

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RE: Membranous Nephropathy treatment 15 hours ago

1:100 titer done last week Sent from my iPhone

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RE: Membranous Nephropathy treatment 15 hours ago

If we were to treat based on plar2I agree kidney biopsy would not change management . There is no suggestion for additional renal disease apart fr...

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RE: Ig A case 15 hours ago

No need to add SGLT2I , in my opinion Not Obese. ------------------------------ Richard Glassock MD, FASN Emeritus Professor Geffen School of Me...

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RE: AI Transparency in Kidney Week Abstract Submissions 15 hours ago

Thanks- disclosure of the use of AI to prepare visuals or posters at Renal Week is optional. ------------------------------ Richard Glassock MD,...

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RE: Membranous Nephropathy treatment 15 hours ago

What would be the point of a repeat biopsy in the face of continued immunological activity of the disease , which needs treatment? What would be ga...

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RE: AI Transparency in Kidney Week Abstract Submissions 15 hours ago

Hi Dr. Glassock. Thanks for clarifying. In abstract submissions, authors should report the use of artificial intelligence, language models, mach...

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RE: Membranous Nephropathy treatment 15 hours ago

Thanks I would stop csa, mmf and give rituximab if serum plar2 is rising I wonder who would consider repeat kidney biopsy as longstanding mn (200...

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RE: Ig A case 15 hours ago

Thanks prof glassock --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------

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RE: yeast peritonitis and return to PD. 16 hours ago

Thanks prof bargman The cohort of 30% patients who got back to pd Did they stay on pd without recurrence of yeast peritonitis/ and achieve good dia...

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RE: Membranous Nephropathy treatment 16 hours ago

If this is a recent value of serum anti-PLa2R antibody (ELISA, in RU/ml), the CsA and MMF should be stopped and therapy with Rituximab or Obinutuzu...

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RE: AI Transparency in Kidney Week Abstract Submissions 16 hours ago

Jim Soo- Thanks but I think you misunderstood the acknowledgement issue. I meant acknowledgment of the use of AI in preparing visuals or posters ...

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RE: AI Transparency in Kidney Week Abstract Submissions 16 hours ago

Hi Dr. Glassock. For Kidney Week abstracts, the "Acknowledgment" field is optional. This is an area to include individuals who contributed to the w...

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RE: Membranous Nephropathy treatment 16 hours ago

Is it going up or down, as the level predicts and precedes proteinuria. can you list all the levels and dates and accompanying proteinuria? (If you...

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RE: Membranous Nephropathy treatment 16 hours ago

100 ------------------------------ James Wells MD Atlanta GA (770) 934-2585 ------------------------------

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RE: yeast peritonitis and return to PD. 17 hours ago

Many thanks No previous peritonitis Been on Apd March 2024 and active on tx list Bw --------------------------------- Muhammad Soobadar MBChB ...

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RE: yeast peritonitis and return to PD. 17 hours ago

I agree that a couple of months should be sufficient. I enclose a review we did of our patients with fungal peritonitis. About 1/3 came back s...

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RE: Membranous Nephropathy treatment 17 hours ago

Do you have serial serum anti PLA2r AB levels? ------------------------------ Roger Rodby MD, FASN Professor of Medicine Rush University Neph...

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RE: yeast peritonitis and return to PD. 17 hours ago

I think two months off PD for fungal peritonitis is long enough to restart PD. Assuming she is cleared by Cardiology and Anesthesia for the surg...

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yeast peritonitis and return to PD. 17 hours ago

Yeast peritonitis Candida parapsilosis 23/03 PD tube removed. On iv antifungal . She has moved to HD 23rd march yeast peritonitis treated wit...

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RE: Membranous Nephropathy treatment 18 hours ago

Thanks. I know what it is. Just did not know the abbreviation. ------------------------------ James Wells MD Atlanta GA (770) 934-2585 ----------...

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RE: Ig A case 18 hours ago

I see no clear need for C inhibition or Nefecon , right now. Maybe Sibeprenlimab in the future l, if approved in UK. Just opinions. -------------...

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RE: Ig A case 18 hours ago

Normal BMI --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------

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RE: Ig A case 18 hours ago

Urine dipstick 3+ blood --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------

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RE: Ig A case 18 hours ago

kidney function has improved to eGFR 60 ml/ Min and proteinuria much improved with 200 mg Sparsentan . I agree about immunologic activity and need...

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RE: Ig A case 18 hours ago

@Richard Glassock I concur and the Uptodate recommendations clearly state that if 3 of 4 criteria are met , start IS meds These include low...

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RE: Ig A case 18 hours ago

With this degree of hemoglobinuria and eGFR impairment - I would give steroids and MMF and not Sparsentan mono therapy. What is his BMI? If obese I...

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RE: Membranous Nephropathy treatment 18 hours ago

Rituximab ( also known as Rituxan ) isp an anti-CD 20 monoclonal antibody ------------------------------ Richard Glassock MD, FASN Emeritus Profe...

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RE: Ig A case 18 hours ago

thanks prof glassock. attached blood work ------------------------------ Muhammad Soobadar MBChB UK ----------------------------...

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RE: AI Transparency in Kidney Week Abstract Submissions 18 hours ago

Do similar acknowledgement requirement also apply to visuals (Powerpoint) for oral presentations at Kidney Week.? What about Poster presentations a...

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RE: Ig A case 18 hours ago

What is the dipstick for hemoglobinuria? What is the current eGFR ? What is current UPCR?Based on the biopsy findings I would add oral moderate dos...

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