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Kidney Week

Abstract: SA-PO1049

Kidney Disease in Pregnancy and Associated Maternal Outcomes

Session Information

Category: Women's Health and Kidney Diseases

  • 2200 Women's Health and Kidney Diseases

Authors

  • Chalk, Cynthia, Kaiser Permanente, San Francisco, California, United States
  • Folck, Bruce F., Kaiser Permanente, San Francisco, California, United States
  • Tucker, Lue-Yen, Kaiser Permanente, San Francisco, California, United States
  • Shirazi, Aida, Kaiser Permanente, San Francisco, California, United States
  • Poyan-Mehr, Ali, Kaiser Permanente, San Francisco, California, United States
Background

Maternal hypertension and CKD have increased over the last thirty years. In this study, we evaluate the prevalence of CKD as defined by GFR and proteinuria at the time of pregnancy and its impact on maternal outcomes during pregnancy.

Methods

We identified 353,735 adult female members of an integrated healthcare system who had one or more pregnancies from 1/2011 to 6/2023. We stratified the cohort into KDIGO's CKD subcategories and assessed the risk of maternal and prenatal outcomes of patients with versus without CKD.

Results

We identified a substantial number of patients with CKD. Clinically and statistically significant differences in maternal and prenatal outcomes exist between those with CKD versus those without. (Please see images for results: Cohort Distrubution and Maternal and Prenatal Outcomes)

Conclusion

Understanding individual risks associated with maternal and prenatal outcomes is critical for CKD patients. Additional analysis is being conducted to define risk in individual CKD subgroups and additional predictors of outcome such as comorbidities, age, and ethnicity.

Cohort Distrubution

Maternal and Prenatal Outcomes