Kidney Week

Abstract: FR-PO046

Preoperative Fasting Time Is Not Associated with Development of AKI after Cardiac Surgery

Session Information

• AKI: Epidemiology, Risk Factors, and Prevention - 2
  October 25, 2024 | Location: Exhibit Hall, Convention Center
  Abstract Time: 10:00 AM - 12:00 PM

Category: Acute Kidney Injury

• 101 AKI: Epidemiology, Risk Factors, and Prevention

Authors

• Schanz, Moritz, Robert-Bosch-Krankenhaus GmbH, Stuttgart, Baden-Württemberg, Germany

Moritz Schanz, DrMed, MBA

• Heidrich, Carmen, Bosch Health Campus, Stuttgart, Baden-Württemberg, Germany

Carmen Heidrich

• Nico, Schmid, Bosch Health Campus, Stuttgart, Baden-Württemberg, Germany

Schmid Nico

• Goebel, Nora, Robert-Bosch-Krankenhaus GmbH, Stuttgart, Baden-Württemberg, Germany

Nora Goebel, MD, PhD

• Oberacker, Tina, Robert-Bosch-Krankenhaus GmbH, Stuttgart, Baden-Württemberg, Germany

Tina Oberacker

• Schricker, Severin, Robert-Bosch-Krankenhaus GmbH, Stuttgart, Baden-Württemberg, Germany

Severin Schricker, MD, DrMed

• Christ, Micha, Bosch Health Campus, Stuttgart, Baden-Württemberg, Germany

Micha Christ

• Latus, Joerg, Robert-Bosch-Krankenhaus GmbH, Stuttgart, Baden-Württemberg, Germany

Joerg Latus, MD

Background

Acute kidney injury (AKI) is associated with high morbidity and mortality, therefore prevention is important. The aim of this study was to systematically assess AKI incidence after cardiac surgery depending on the preoperative fasting time.

Methods

This single-center study included n = 8423 patients who had cardiac surgery at Robert Bosch Hospital, Stuttgart (Germany) between 2017 and 2024. All patients scheduled for surgery the next day stop eating and drinking at midnight, irrespective the time of surgery. AKI was classified according to the full definition of Kidney Disease: Improving Global Outcomes (KDIGO), including urinary output.

Results

In our cohort, overall postoperative AKI incidence was 71% during hospital stay. Interestingly, patients with AKI stage 1-3 had significant longer preoperative fasting time compared to patients without AKI (p=0.036; OR 1.15 (IQR 1.05-1.27)). However, after adjusting for important confounding factors e. g. urgency of surgery, age, pre-existing conditions such as CKD, heart failure, obesity, as well as aortic clamping time, duration of surgery, the association was no longer evident (p=0.39; OR 1.07 (0.92-1.25)).

Conclusion

Although preoperative fasting time seems to be a plausible risk factor for AKI development, this study provides evidence that preoperative fasting time is not a risk factor for the development of AKI after cardiac surgery after adjustment for potential confounders.