Abstract: SA-PO981
Racial and Relationship Trends in Living Kidney Donation: A Retrospective Analysis from Miami Transplant Institute
Session Information
- Transplantation: Clinical - 3
October 26, 2024 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Transplantation
- 2102 Transplantation: Clinical
Authors
- Del Castillo Rix, Daniel Sebastian, Jackson Memorial Hospital, Miami, Florida, United States
- Ortigosa Serrano, Veronica A., University of Miami, Coral Gables, Florida, United States
- Medina, Adriana, Ross University School of Medicine - Barbados Campus, Bridgetown, Barbados
- Esmail, Rojin, Ross University School of Medicine - Barbados Campus, Bridgetown, Barbados
- Cabeza Rivera, Franco H., Jackson Memorial Hospital, Miami, Florida, United States
Background
Living kidney donation is pivotal in combating end-stage renal disease, offering superior outcomes and reduced waiting times compared to deceased donor transplants. Understanding the relationship between donors and recipients, particularly across various racial and ethnic groups, is crucial for developing targeted strategies to increase donor recruitment and improve transplant equity, ultimately enhancing patient outcomes in transplant medicine.
Methods
We retrospectively reviewed the clinical data of seven hundred seventy donors who underwent nephrectomy for living donor kidney transplantation at the Miami Transplant Institute from 2011 to 2021. We evaluated the relationships between living kidney donors and recipients and how they varied across racial and ethnic groups over time. We used descriptive statistics to describe the changes in living kidney donors and chi-squared to determine its statistical significance. Logistic regression was used to determine differences in relationships by race over time statistical significance was set at a p-value <0.05, with analyses performed using STATA/BE, version 17.
Results
We included 770 patients, who were categorized into three primary groups: White (266 participants, 34.8%), Black (155 participants, 20.1%), and Latino (347 participants, 45.1%). Within these groups, the total number of related donors varied: 122 (45.5%) in the White group, 107 (69%) in the Black group, and 192 (55.3%) in the Latino group. Logistic regression revealed no significant differences in the trends of kidney donation over time.
Conclusion
This retrospective analysis underscores the complexities of living kidney donation across our different groups. Despite variances in the proportion of related donors among White, Black, and Latino groups, our findings indicate no significant changes in the trends of kidney donation relationships over time. However the proportion of related donors is notably higher in the Black and Latino group compared to white. This suggests underlying social and cultural differences in living kidney donation attitudes that could be addressed by incentivizing culturally sensitive programs. Further studies need to be done to better understand what factors influence differences in relationships.