Abstract: FR-PO1094
Global Burden of CKD in Individuals 20 Years and Older in 204 Countries and Territories, 1990-2021
Session Information
- CKD: Epidemiology, Risk Factors, and Prevention - 2
October 25, 2024 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: CKD (Non-Dialysis)
- 2301 CKD (Non-Dialysis): Epidemiology, Risk Factors, and Prevention
Authors
- Hirpara, Ishita Dineshbhai, GMERS Medical College Junagadh, Junagadh, Gujarat, India
- Potluri, Geethika Chandra, Dr YSR University of Health Sciences, Vijaywada, Andhra Pradesh, India
- Dekhne, Anushka, American University of Antigua, Coolidge, Antigua and Barbuda
- Bollu, Sashank Sai, Gandhi Medical College, Secunderabad-Padmarao Nagar, Telangana, India
- Anne, Sai Nitya Tejaswi, Gandhi Medical College, Secunderabad-Padmarao Nagar, Telangana, India
- Gera, Asmita, Tianjin Medical University, Tianjin, China
- Desai, Hardik, Gujarat Adani Institute of Medical Science, Bhuj, Gujarat, India
Background
The impact of CKD in individuals <20 is profound, affecting their physical health, quality of life, and psychosocial development. The study was aimed at assessing global epidemiological trend of CKD <20 years of age.
Methods
Employing the Global Burden of Disease 2021 framework, we estimated incidence, prevalence, deaths, disability-adjusted life years (DALYs), year lived with disabiliy (YLDs) stratified by age, sex, and year across 204 countries and territories from 1990-2021 for individuals <20 years old.
Results
The total percentage of change (TPC) in prevalence increased by 21% (95%UI: 19-23%), incidence by 20% (14-27%) from 1990-2021. However, there was a decrease in DALYs by 22% and in deaths by 23% over the last three decades. Regionally, the highest TPC in CKD incidence was observed in central Africa by 141%. The Low Sustainable Development Index (SDI) countries exhibited the most significant increases in deaths (32%) and DALYs (33%) from 1990-2021. The unadjusted incidence rate in the 15-19 age group rose by 44%, followed by a 37% increase in 10-14 age group from 1990-2021. Gender disparities were evident in the burden of CKD, with males experiencing a higher overall impact. The TPC in incidence for males increased by 25% compared to 15% for females from 1990-2021.
Conclusion
CKD accounted for 0.43% deaths amongst all casualties in 2021 <20 years old. The study highlights the urgent need for targeted interventions and resources to address the escalating prevalence of CKD in young individuals, particularly in regions with the highest incidence rates and in countries with low SDI countries.