Abstract: TH-PO957
Nutritional Status and Sleep Quality in Adult Patients with CKD
Session Information
- Physical Activity and Lifestyle in Kidney Diseases
October 24, 2024 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Health Maintenance, Nutrition, and Metabolism
- 1500 Health Maintenance, Nutrition, and Metabolism
Authors
- Ortiz, Ailema Janeth Gonzalez, Instituto Nacional de Pediatria, Mexico City, Mexico City, Mexico
- Rodriguez Gonzalez, Norberto, Instituto Mexicano del Seguro Social, Ciudad de Mexico, Mexico
- Mendoza Mayorga, Ingrid, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Ciudad de Mexico, Ciudad de México, Mexico
- Ramos-Acevedo, Samuel, McMaster University, Hamilton, Ontario, Canada
- Lopez-Cisneros, Sonia, Instituto Nacional de Geriatria, Ciudad de Mexico, Ciudad de México, Mexico
- Espinosa-Cuevas, Angeles, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Ciudad de Mexico, Ciudad de México, Mexico
Background
Sleep and appetite disorders share common mechanisms and have been shown to impact metabolic disorders in the general population. Patients with chronic kidney disease (CKD) often experience sleep disturbances, but whether these are associated with their nutritional status is unknown. We aimed to determine the relationship between measures of nutritional status and sleep quality in adult patients with non-dialysis-dependent CKD.
Methods
Cross-sectional cohort study including adult patients with estimated glomerular filtration rate (eGFR)<60 ml/min/1.73m2 attending nephrologist consultations. Patients with amputations or metallic plates, diagnosed psychiatric disorders, and using medications with a direct effect on sleep were excluded. All patients responded to the Pittsburgh sleep quality questionnaire (PSQI) and underwent a full nutritional assessment including subjective global assessment (SGA), bioelectrical impedance, anthropometry, and 24-hour recall. Multivariate regression was used to analyze the associations between measures of nutritional status and sleep quality (Odd Ratios with 95% confidence intervals).
Results
A total of 106 participants , median age 52 (38-66) years. Hypertension was present in 62% of participants and diabetes in 46%. The majority (75%) of participants presented poor sleep quality (PSQI ≥5), and a total of 35% were considered malnourished (SGA>1). Compared to well-nourished patients, malnourished patients were more likely higher systolic blood pressure, lower serum albumin, and lower eGFR, (p<0.05 for all). No significant differences in age, gender, comorbidities, or dietary energy intake were observed. Malnourished patients also reported higher PSQI scores (worse sleep quality, median score 10 vs 7, p <0.01). In multivariable logistic regression adjusting for age, sex, eGFR, energy intake, and comorbidities, the Odds of malnutrition increased by 18% (OR 1.18, 95% CI 1.04 to 1.33) for unit increase in PSQI).
Conclusion
Most patients with non-dialysis dependent CKD reported poor sleep quality, and its severity was associated with the presence of malnutrition as assessed by SGA.