Abstract: SA-PO1062
Perinatal Outcomes and Risk Factors for Fetal Growth Restriction in Kidney Transplant Recipients: A Retrospective Cohort Study
Session Information
- Women's Health and Kidney Diseases
October 26, 2024 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Women's Health and Kidney Diseases
- 2200 Women's Health and Kidney Diseases
Authors
- Alamri, Nada, Madinah Health Cluster, Ministry of Health, Madinah, Saudi Arabia
- Altaifi, Hatoon, Imam Abdulrahman Bin Faisal University, Dammam, Eastern, Saudi Arabia
- Aleid, Hassan A., King Faisal Specialist Hospital and Research Centre, Riyadh, Riyadh, Saudi Arabia
Background
Pregnancy outcomes have significantly improved in women with end-stage renal disease following renal transplantation. Despite this, these women still face higher rates of adverse outcomes, including intrauterine growth restriction (IUGR). This study aims to report perinatal outcomes and identify risk factors for IUGR in kidney transplant recipients.
Methods
This retrospective cohort study included 40 women who conceived after receiving a kidney transplant. We compared pregnancies complicated by IUGR with those that had normal fetal growth, focusing on identifying significant risk factors.
Results
IUGR was identified in 8 (21%) cases, with fetal weight below the 10th percentile. Significant risk factors for IUGR included proteinuria (P = 0.03), nulliparity (P = 0.04), and age at the time of transplant (P = 0.03). No significant associations were found with anemia, hypertension, maternal age, or pre-pregnancy creatinine levels. Increased incidences of pre-eclampsia (40%), placental abruption (12.5%), preterm delivery (29%), and cesarean section (66%) were observed.
Conclusion
IUGR is a common adverse outcome among pregnant women post-renal transplantation. Proteinuria, nulliparity, and age at transplant are significant risk factors for IUGR. These findings highlight the importance of targeted monitoring and management in this high-risk population. Future research should include long-term pediatric follow-up to better understand the outcomes for children born to this group of women.
Prenatal Outcome in Relation to Pregnancy Timing After Renal Transplant