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Kidney Week

Abstract: FR-OR91

Global, National, and Regional Trends in the Burden of CKD among Women from 1990-2021: A Comprehensive Global Analysis

Session Information

Category: Women's Health and Kidney Diseases

  • 2200 Women's Health and Kidney Diseases

Authors

  • Purohit, Sree Abhilekha, Shadan Institute of Medical Sciences College of Nursing, Hyderabad, Telangana, India
  • Pudhota, Harsha Choudary, Guntur Medical College, Guntur, Andhra Pradesh, India
  • Shandilya, Ashwinikumar, Pravara Institute of Medical Sciences (Deemed to be University), Ahmednagar, India
  • Reddy, Ram Prasanjith, MediCiti Institute of Medical Sciences, Medchal, Telangana, India
  • Lakkimsetti, Mohit, Mamata Medical College, Khammam, Telangana, India
  • Amin, Vishrant, Gujarat Medical Education and Research Society Medical College & Hospital Valsad, Valsad, Gujarat, India
  • Patel, Juhi, Gujarat Medical Education and Research Society Medical College & Hospital Valsad, Valsad, Gujarat, India
  • Raj, Rohan, Nalanda Medical College and Hospital, Patna, Patna, India
  • Desai, Hardik, Gujarat Adani Institute of Medical Science, Bhuj, Gujarat, India
Background

Chronic Kidney Disease (CKD) ranked as the 7th leading cause of death among women in 2021. This pioneering study presents the 1st comprehensive evaluation of the global burden of CKD in women over the past 3 decades, including an analysis of the initial 2 years of the COVID-19 pandemic-a period that significantly challenged the management of non-COVID-19 diseases.

Methods

Utilizing the 2021 GBD Study framework, we estimated the prevalence, incidence, mortality, Disability Adjusted Life Years(DALYs),and Years Lived with Disability(YLDs) by age,year,and location across 204 countries and territories.

Results

The average annual percentage change(AAPC) in prevalence increased by 2.10%, mortality by 3.39%, and DALYs by 2.48%. Regionally, we observed the highest incidence rates of CKD due to Type 1 diabetes occurred in Eastern Europe (2.07 cases per 100,000 persons), while CKD due to Type 2 diabetes led in the Middle East and North Africa(MENA) with 43 cases per 100,000 persons. Additionally, CKD attributed to hypertension(HTN) (25.18 cases per 100,000 persons) and glomerulonephritis (5.69 cases per 100,000 persons) were notably prevalent in MENA and Central Latin America, respectively. The most substantial incidence counts were observed in the 70-74 age group with 1,663,821 cases, while the highest death rates occurred among those aged 85-89, totaling 92,279 in 2021.

Conclusion

Type 2 DM was the leading cause of CKD related deaths among women in 2021, followed by CKD due to HTN. There is a critical need for increased awareness, education, and comprehensive campaigns aimed at women's health involving public stakeholders and clinicians to address and mitigate these impacts.