Abstract: SA-PO020
Can Automated Digital Counseling Enhance Mental Health in Patients with Chronic Heart Failure or Kidney Disease? The ODYSSEE-vCHAT Study
Session Information
- Augmented Intelligence, Large Language Models, and Digital Health
October 26, 2024 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Augmented Intelligence, Digital Health, and Data Science
- 300 Augmented Intelligence, Digital Health, and Data Science
Authors
- Auguste, Bourne L., University of Toronto Temerty Faculty of Medicine, Toronto, Ontario, Canada
- Montbriand, Janice, University Health Network, Toronto, Ontario, Canada
- Chan, Christopher T., University Health Network, Toronto, Ontario, Canada
- Nolan, Robert, University Health Network, Toronto, Ontario, Canada
Group or Team Name
- ODYSEE-vCHAT Investigators.
Background
Chronic Kidney Disease (CKD) and Chronic Heart Failure (CHF) significantly impact morbidity, mortality, and quality of life. We evaluated the ODYSSEE-vCHAT automated digital counseling program, including social network support, to enhance mental health and quality of life in patients with CHF and CKD. The primary aim was to assess the effect of ODYSSEE-vCHAT on Mental Component Summary (MCS) of the SF-36 health survey.
Methods
This 11-month, multicenter, open-label trial evaluated adults with CHF (reduced EF) or CKD (2-year KFRE≥ 10%), focusing on self-care skills (medication adherence, exercise, diet, smoke-free living) via a digital platform. The primary outcome was achieving a minimal clinically important difference in MCS (ΔMCS ≥ 3.8 or MCS ≥ 65).
Results
Of 215 enrolled participants, 174 completed the study, with a mean age of 54.4 years; 61% (n=106) had CKD. Significant improvements in MCS scores were noted for both CKD and CHF patients. However, no statistically significant changes were found in KDQOL or MCS scores for CKD patients alone, though small-to-moderate effect sizes were observed: Vitality (0.40, p=0.16), Emotional Well-Being (-0.11, p=0.70), Social Functioning (-0.37, p=0.19), Role Limitations (0.43, p=0.12), aggregate MCS (0.15, p=0.60), and KDQOL Subscale CKD Burden (0.36, p=0.12). These suggest meaningful small-to-moderate improvements (Fig 1). Participants experienced reduced CKD burden and enhanced quality of life.
Conclusion
The ODYSSEE-vCHAT program showed potential in enhancing mental health and quality of life among CKD patients, indicating value in digital health interventions in managing chronic diseases. These findings underscore the need for further trials to establish the efficacy of digital counseling in CKD patient care.
Figure 1. Change in KDQOL-CKD Burden Scale (End of Study – Baseline) by Program Engagement
Funding
- Other NIH Support