Abstract: FR-PO243
Trend Analysis of Kidney Stone-Related Mortality, 1999-2020
Session Information
- Mineral Bone Disease: Transplant and Kidney Stones
October 25, 2024 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Bone and Mineral Metabolism
- 502 Bone and Mineral Metabolism: Clinical
Authors
- Munir, Luqman, King Edward Medical University, Lahore, Pakistan
- Chaudhary, Ahmed Jamal, Detroit Medical Center, Detroit, Michigan, United States
- Ammar ur Rahman, Mohammad, King Edward Medical University, Lahore, Pakistan
- Khalid, Amna, King Edward Medical University, Lahore, Pakistan
- Ijaz, Azka, King Edward Medical University, Lahore, Pakistan
Background
Kidney stones (KS) are hard deposits that can form inside the kidney or the urethra, obliterating the flow of urine and causing sharp pain. It might consist of calcium oxalate, uric acid and struvite. The stones may pass in urine painlessly, if hydrated enough or may require procedure like lithotripsy for treatment.
This study explores the trend of deaths in the US from 1999 to 2020 in relation to kidney stones using age adjusted mortality rate (AAMR) to identify disparities among specific epidemiological groups (age ,gender ,race ,urban/rural).
Methods
Our research involved analysis of death certificates between 1999 to 2000 obtained from the Centers for Disease Control and Prevention Wide Ranging Online Data for Epidemiologic Research (CDC Wonder) database related to AAMR per 100,000 people. And annual percentage change (APC) with 95% confidence interval were determined. Joinpoint regression Program was used to conduct test for parallelism and to determine variations among key demographic groups. (age ,gender ,race ,urban/rural).
Results
A total of 18,539 deaths were recorded in relation to kidney stones from 1999 to 2020 in the US. The AAMR trend is increasing as it was 2.269 in 1999 and 3.554 in 2020. The recorded APC from 1999 to 2014 was 0.4719 and from 2014 to 2020 was 6.1495. There were higher mortality rates in Whites, males, those aged >85 years, and those residing in rural and western areas. Tests for parallelism revealed disparate trends across Male and Female (p=0.002222), Black and White races (p=0.004222), South and West (p=0.004889), Northeast and South (p=0.002444), Midwest and northeast (p=0.043111) and urban vs. rural demographics(p=0.012000).
Conclusion
An upward trajectory has been seen in kidney stones related deaths from 1999 to 2020. This accentuates the need for further research in kidney health to minimize such rates in upcoming years.