Abstract: SA-PO1101
Trend Analysis of Chronic Kidney Failure-Related Mortality, 1999-2020
Session Information
- CKD: Epidemiology, Risk Factors, and Prevention - 3
October 26, 2024 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: CKD (Non-Dialysis)
- 2301 CKD (Non-Dialysis): Epidemiology, Risk Factors, and Prevention
Authors
- Munir, Luqman, King Edward Medical University, Lahore, Pakistan
- Chaudhary, Ahmed Jamal, Detroit Medical Center, Detroit, Michigan, United States
- Sohail, Sara, King Edward Medical University, Lahore, Pakistan
- Fatima, Kanwal, King Edward Medical University, Lahore, Pakistan
- Khalid, Amna, King Edward Medical University, Lahore, Pakistan
- Ammar ur Rahman, Mohammad, King Edward Medical University, Lahore, Pakistan
- Azeem, Saleha, King Edward Medical University, Lahore, Pakistan
Group or Team Name
- NEURALKEy.
Background
The hallmark of chronic renal failure, also called chronic kidney disease, is a progressive decline in kidney function over time. Multiple etiologies for the illness may exist, such as glomerulonephritis, diabetes, and hypertension. High risk of heart failure, weak bones, and anemia are just a few of the many complications that may result.
Methods
We reviewed the CRF mortality data obtained from the CDC WONDER (Wide-Ranging Online Data for Epidemiological Research) Database, which spans the years 1999 to 2020. Using 95% confidence intervals, the Joinpoint Regression Program computed annual percent changes (APC) and AAMR per 1,000,000 individuals. For p<0.05, the parallelism test was deemed significant for non-parallel results.
Results
A total of 1,938,505 CRF-related deaths were reported between 1999 and 2020. With an APC of 1.33, AAMR demonstrated an increasing trend. Between 2010 and 2012, there was a noticeable peak, which was followed by a decline. Blacks or African Americans, males, non-metropolitan population, and people 85 years or older showed higher death rates. Disparate trends were found in the tests for parallelism among gender (p=0.0002), Blacks and Whites (p=0.002), Northeast and Midwest (p=0.004), Midwest and South (p=0.02), and Midwest and West (p=0.02). However, the parallelism test between urban and rural areas was not significant (p=0.07).
Conclusion
In the United States, the number of deaths from CRF has increased significantly over the last 20 years, possibly because early-stage CKD is frequently asymptomatic. Certain demographic groups continue to have higher death rates, which emphasizes the need for more research.