Abstract: SA-PO334
Trend Analysis of Diabetic Kidney Disease-Related Mortality, 1999-2020
Session Information
- Diabetic Kidney Disease: Clinical Pathology, Diagnostic and Treatment Advances
October 26, 2024 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Diabetic Kidney Disease
- 702 Diabetic Kidney Disease: Clinical
Authors
- Ammar ur Rahman, Mohammad, King Edward Medical University, Lahore, Pakistan
- Chaudhary, Ahmed Jamal, Detroit Medical Center, Detroit, Michigan, United States
- Ghouri, Gul Sher, King Edward Medical University, Lahore, Pakistan
- Munir, Luqman, King Edward Medical University, Lahore, Pakistan
- Khalid, Amna, King Edward Medical University, Lahore, Pakistan
- Azhar, Natalia, King Edward Medical University, Lahore, Pakistan
- Saeed, Abdullah, King Edward Medical University, Lahore, Pakistan
Group or Team Name
- NEURALKEy.
Background
A dangerous consequence of diabetes called diabetic kidney disease (DKD) is the progressive loss of kidney function. It results from long-term unchecked blood sugar levels that harm the kidneys' filtering organs. To lessen its influence on general health, early identification and treatment are essential.
The mortality due to Diabetic Kidney Disease is on the rise in the United States. In this study we explored these trends from 1999-2020, using age adjusted mortality rates (AAMR) to pinpoint incongruities between epidemiological groups
Methods
Our study conducted an in-depth search of the CDC Wonder database, based on the incidence of sequalae of stroke-related Age-Adjusted Mortality Rate (AAMR) per 100,000 individuals. Employing Join point Regression Analysis, we assessed Parallelism and computed Annual Percent Changes (APC) with a 95% Confidence Interval. For a p<0.05, the test of parallelism was considered significant for unparallel.
Results
From 1999-2020, a total of 34195 deaths were reported due to diabetic kidney disease. The overall AAMR showed a rise from 1999-2014, with an APC of 30.62. Following this, the AAMR started to rise again from 2014-2020, with an APC of 11.5. The highest mortality populations were males and African Americans. The geographical hotspots for mortality were rural and west. Tests for parallelism revealed disparate trends across gender (p=0.012), African American races (p=0.033), urban versus rural demographics (p=0.007). However, the parallelism test in west (p=0.029) was not significant.
Conclusion
The recent rise in the mortality due to Diabetic Kidney Disease is concerning. Furthermore, the disparity among the demographic variables warrants more investigation, and the planning of targeted interventions.