Abstract: PUB561
Prevalence of Albuminuria and Risk Factors for CKD in a Screening Program in Mexico
Session Information
Category: CKD (Non-Dialysis)
- 2301 CKD (Non-Dialysis): Epidemiology, Risk Factors, and Prevention
Authors
- Ardavin Ituarte, Juan M., Medica Santa Carmen, Mexico City, Mexico, Mexico
- Pineirua, Alicia, Medica Santa Carmen, Mexico City, Mexico, Mexico
- Solis, Edgar, Medica Santa Carmen, Mexico City, Mexico, Mexico
- Hernández-Estrada, Sergio, Medica Santa Carmen, Mexico City, Mexico, Mexico
Group or Team Name
- Medica Santa Carmen.
Background
"Check Your Kidney" (CYK) is a screening program to assess for risk factors of CKD in a Renal Health Network in Mexico. The present study reports the prevalence of albuminuria and CKD risk factors in CYK participants.
Methods
In 2023, 8 CYK campaigns took place in 5 HD clinics across Puebla, Mexico City, Jalisco, and Guanajuato. Evaluation included a risk factor questionnaire, anthropometric measurements, BPM, glucometer, and urine albumin/creatinine ratio tests. Chi-square, Student's t-test, and Mann-Whitney U test were used for analysis where applicable, along with multiple logistic regression, to assess the risk of albuminuria.
Results
A total of 1089 participants were evaluated, with a mean age of 47 years ± 15); 61% were women. The most common CKD risk factor was obesity, with 76% of participants having a BMI ≥ 25 and 35% > 30. This was followed by chronic use of potentially nephrotoxic medications in 26%, known hypertension (HTN) in 23%, and known diabetes mellitus (DM2) in 15%. Capillary glucometry identified 20 additional participants with probable undiagnosed DM2 (random capillary glucose > 200 mg/dL) for a total prevalence of 17%, and blood pressure measurement (SBP ≥ 160 or DBP ≥ 100) identified 44 more with probable HTN for a total prevalence of 27%. Albuminuria > 30 mg/g was detected in 25% and ≥ 300 mg/g in 2% of all participants; in 39% (p < 0.001) and 7% (p < 0.001) respectively of participants with DM2; and in 36% (p > 0.001) and 3% (p=0.16) of participants with HTN. The risk association remained significant only for DM2 in the logistic regression analysis after adjusting for age, sex, and other reported risk factors, with an OR = 1.72 (CI 1.19 - 2.49, p = 0.004) for albuminuria > 30 mg/g and OR = 6.17 (CI 2.36 - 16.1, p < 0.001) for albuminuria ≥ 300 mg/g. Four percent of the patients had all three risk factors (DM2, HTN, and obesity); however, no interaction effect was found between these covariates for the risk of albuminuria.
Conclusion
The prevalence of albuminuria was higher than reported in other populations, but there may be measurement and selection bias. The prevalence of obesity, DM2, and HTN is consistent with that reported in the Mexican population. The most relevant risk factor for albuminuria, as expected, was DM2.
Funding
- Clinical Revenue Support