Abstract: PUB176
Outcome of Peripheral Arterial Disease in Patients with ESKD on Hemodialysis
Session Information
Category: Dialysis
- 801 Dialysis: Hemodialysis and Frequent Dialysis
Authors
- Oweis, Ashraf Omar, Jordan University of Science and Technology Faculty of Medicine, Irbid, Jordan
- Alshelleh, Sameeha A., The University of Jordan, Amman, Amman, Jordan
Background
Patients on hemodialysis are at higher risk for cardiovascular complications due to increased risk of atherosclerosis. This has been associated with higher morbidity and mortality rates. Peripheral arterial disease (PAD) is an important complication of atherosclerosis that is manifested significantly in these patients. However, it has not been extensively studied in our region.
Methods
A retrospective analysis was performed from the years 2010- 2021. ESRD patients that were diagnosed with PAD during this period were studied, diagnosis was done through CT- Angiography. Predefined end points were death and amputation
Results
The mean age for the patients was 65.9 (SD± 12.96). Most patients were either with DM (84.6%) or HTN (91%).The prevalence of amputation was 44.7%, using univariate analysis DM was a strong predictor for amputation (P=0.001) as long as coronary artery disease (P=0.001).
On multivariate analysis only DM (P=0.003) was associated with higher prevalence of amputation Time to death was 16.9 months (SD±25.6), 11.3 months (SD±9.1) for patients with amputation vs. 21.1 (SD±32.7) for those without amputation
Conclusion
End stage renal disease patients with PVD especially with PVD have higher mortality and majority are diabetic which necessitate earlier recognition of PVD and modified risk factors like better control of DM and its complications in addition to other risk factors like HTN, dyslipidemia and metabolic disorders of CKD.