Kidney Week

Abstract: TH-PO287

Comparison of Daily Physical Activity between Dialysis Periods in Patients Undergoing Sessions Three Times per Week

Session Information

• Hemodialysis and Frequent Dialysis - 1
  October 24, 2024 | Location: Exhibit Hall, Convention Center
  Abstract Time: 10:00 AM - 12:00 PM

Category: Dialysis

• 801 Dialysis: Hemodialysis and Frequent Dialysis

Authors

• Fuentes Mercado, Alfredo, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Estado de Mexico, Mexico

Alfredo Fuentes Mercado, MD

• Gil, Salvador Lopez, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Estado de Mexico, Mexico

Salvador Lopez Gil, MD

• Jaime Borja, Erika Elizabet, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Estado de Mexico, Mexico

Erika Elizabet Jaime Borja, MS

• Gopar-Nieto, Rodrigo, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Estado de Mexico, Mexico

Rodrigo Gopar-Nieto, MSc

• Martinez Amezcua, Pablo, Johns Hopkins University, Baltimore, Maryland, United States

Pablo Martinez Amezcua, MD, PhD

Background

Patients undergoing hemodialysis are significantly less active than healthy sedentary controls. Particularly on hemodialysis days, they have fewer steps than on interdialytic days. Accelerometers are non-invasive wearable devices that measure the acceleration of the body part they are attached to. We aimed to describe daily physical activity in patients undergoing hemodialysis sessions thrice a week and quantify differences in daily activity across inter-dialytic days and dialytic days.

Methods

This was a cross-sectional study. Patients 18 and older undergoing HD without contraindications for physical activity or major mobility limitations were included. Physical activity was measured with a wrist-worn triaxial accelerometer (ActiGraph GT9X, Pensacola, FL). Participants wore the device continuously on the non-dominant wrist for 4-8 days. Valid days had≥90% of wear time. We derived total activity counts (TAC), daily active time, and the active-to-sedentary transition probability (ASTP–a measure of activity fragmentation). We estimated differences in activity measures across interdialytic periods with mixed-effects linear models to account for the clustering of observations.

Results

Among 27 participants (mean age=39.6, [SD=12.5]; 40.7% female), the mean TAC was 2.34 million (SD=0.77 million), mean active time was 446.8 (SD=137.12) minutes, and mean ASTP was 0.25 (SD=0.07). Physical activity was lower (mean active time= -103 minutes [1 hr and 43 mins], 95% CI: -148.5 to –58.6; TAC –0.7 million, 95% CI –0.9 to -0.4), and more fragmented (AST= 0.05, 95% CI 0.03 to 0.07) on dialysis days compared to interdialytic days.

Conclusion

Our findings indicate that physical activity levels are lower and more fragmented during dialysis than interdialytic days. Future efforts should focus on promoting physical activity on dialytic days.

Activity count for a week of one of the participants in our study, an example of the data we analize for the results.