Kidney Week

Abstract: PUB510

Association of Postdonation Kidney Function and Risk of CKD in Living Kidney Donors at the Civil Hospital of Guadalajara, Mexico

Session Information

• Publication Only

Category: Transplantation

• 2102 Transplantation: Clinical

Authors

• Camacho, Jahir Ricardo, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico

Jahir Ricardo Camacho, MD

• Navarro Blackaller, Guillermo, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico

Guillermo Navarro Blackaller, MD

• Carmona, Edgar Joel, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico

Edgar Joel Carmona, MD

• De la Torre De la Vega, Ixchel, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico

Ixchel De la Torre De la Vega, MD

• Chavez, Jonathan, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico

Jonathan Chavez, PhD

• Medina, Ramon, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico

Ramon Medina, MD

• Correa de León, Juárez, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico

Juárez Correa de León, MD

• Cruz Aragon, Fernando, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico

Fernando Cruz Aragon, MD

• Alcantar Vallin, Maria de la Luz, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico

Maria de la Luz Alcantar Vallin, MD

Background

In Mexico, according to figures from the National Transplant Center Registry, more than 90% of transplants are from living donors.This makes it difficult to estimate the risk attributable to donation.
The outcome of donors in our country is unknown, in terms of risk of progression to CKD and comorbidities. In previous studies, some of which do not confer a higher risk, mainly in the first-world population.

Methods

Cross-sectional cohort study without retrospective intervention, Unicentro, of kidney donor patients from the program of the Civil Hospital of Guadalajara. In the period from January 2019 to December 2022, at the 5-year follow-up.
Objective: Association of post-donation renal function from the year of donation and risk of chronic kidney disease with a 30% loss of GFR, renal replacement therapy.

Results

found with an average age of 39 years in total. The 93.2% (124) of donors do not have social or private security. The eGFR before donation was 102.21 ml/min/1.73 m2. (DE +/ 7.65ml/min/1.73m2) . Only 11.1% achieved renal MAKE.
+ The estimated glomerular filtration rate was compared with the CKD-EPI formula with serum creatinine, baseline eGFR with a mean of 102.21 ml/min/1.73m2 SD +/- 7.65 ml/min/1.73m2 and at follow-up at the fifth year with a mean 80.5ml/min/1.73m2 SD +/- 9.78 ml/min/1.73m2 with a decrease in eGFR with a non-significant value of p=0.8438.
+ Kidney donors were analyzed, comparing their baseline pre-kidney donation BMI (26.4 kg/m2 SD +/- 1.78 kg/m2), at follow-up BMI 27.3 kg/m2 SD +/- 9.3 kg/m2 with a significant difference of p=0.0162Conclusion

Conclusion

In this study, we observed that although there was a significant difference in renal function at 5 years post-transplant,, but 11.2% of our population had it MAKE RENAL. .