Abstract: FR-PO043
Perioperative Kidney Function and AKI in Noncardiac Surgery: A Retrospective Cohort Study in Brasília, Brazil
Session Information
- AKI: Epidemiology, Risk Factors, and Prevention - 2
October 25, 2024 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Acute Kidney Injury
- 101 AKI: Epidemiology, Risk Factors, and Prevention
Authors
- dos Santos, Petherson Mendonça, Universidade Federal de Sao Paulo Escola Paulista de Medicina, Sao Paulo, SP, Brazil
- Rodrigues Lacerda, Kirliane De Sousa, Centro Universitario Unieuro, Brasilia, Distrito Federal, Brazil
- Rodrigues De Lacerda, Rafael Feitosa, Secretaria de Estado da Saude do Distrito Federal, Brasilia, DF, Brazil
- Gatto, Yvve Priscilla, Secretaria de Estado da Saude do Distrito Federal, Brasilia, DF, Brazil
- Lima, Gleidson Tavares, Hospital da Crianca de Brasilia Jose Alencar, Brasília, Distrito Federal, Brazil
- Lara, Débora Cristina Aleixo, Hospital Universitario de Brasilia, Brasilia, Distrito Federal, Brazil
- Pinheiro, Lucas Andrade, Universidade de Brasilia Faculdade de Medicina, Brasilia, FD, Brazil
- Oliveira, Priscila de Matos Bastos, Secretaria de Estado da Saude do Distrito Federal, Brasilia, DF, Brazil
- Verner, Glayson Carlos Miranda, Secretaria de Estado da Saude do Distrito Federal, Brasilia, DF, Brazil
- Garcia, Carolina Suzuki, Universidade Federal de Sao Paulo Escola Paulista de Medicina, Sao Paulo, SP, Brazil
- Andrade, Jessica Liara Felicio de, Universidade Federal de Sao Paulo Escola Paulista de Medicina, Sao Paulo, SP, Brazil
- Bertoso de Vasconcelos Freire, Lucyana, Escola Superior de Ciencias da Saude, Brasilia, DF, Brazil
- da Fonseca, Cassiane Dezoti, Universidade Federal de Sao Paulo Escola Paulista de Enfermagem, Sao Paulo, São Paulo, Brazil
- Goes, Miguel Angelo, Universidade Federal de Sao Paulo Escola Paulista de Medicina, Sao Paulo, SP, Brazil
Group or Team Name
- Postgraduate Program in Nephrology at the Paulista School of Medicine at the Federal University of São Paulo.
Background
Acute Kidney Injury (AKI) remains a significant complication in the perioperative period, associated with increased morbidity and mortality. This study aimed to evaluate the frequency and clinical factors associated with perioperative AKI in patients undergoing noncardiac surgery and to assess the predictive value of the SPARK – Simple Postoperative AKI Risk.
Methods
A retrospective study with 172 noncardiac surgery patients from 2021 to 2022 at a teaching hospital in Brasilia, Brazil. The study population included patients of various ages, genders, and comorbidities who underwent a range of noncardiac surgeries. Demographic and clinical data, such as kidney function (measured by creatinine levels), American Society of Anesthesiologists (ASA) score pre-surgery, and outcomes (including length of hospital stay and need for kidney replacement therapy), were compared between AKI and non-AKI groups. Finally, we performed a multivariate analysis and analyzed SPARK’s index discrimination with the ROC curve.
Results
60 (34.9%) patients developed AKI. Older age and higher ASA scores were significantly associated with AKI (p<0.001), and RDW was identified as a predictor of AKI (IRR 1.28%, 95% CI: 1.04-1.57, p= 0.017). Patients with AKI had more extended surgery. Exposure to nephrotoxic agents and blood transfusion requirements were also higher in the AKI group. The SPARK index showed the AUC of 0.72 (95% CI, 0.65-0.80).
Conclusion
Preoperative RDW levels, in addition to age and ASA score, were independently associated with AKI in noncardiac surgeries. The SPARK score, with its AUC of 0.72, is a valuable tool for preoperative risk assessment. These results underscore the complexity of risk factors associated with AKI in the perioperative setting of noncardiac surgeries. Further research is needed to validate the findings and enhance AKI prevention strategies.