Kidney Week

Abstract: TH-PO1005

A Comprehensive Report on Patients with CKD in the CDC NHANES Cohort, 2001-2020

Session Information

• CKD: Epidemiology, Risk Factors, and Prevention - 1
  October 24, 2024 | Location: Exhibit Hall, Convention Center
  Abstract Time: 10:00 AM - 12:00 PM

Category: CKD (Non-Dialysis)

• 2301 CKD (Non-Dialysis): Epidemiology, Risk Factors, and Prevention

Author

• Asghar, Muhammad Sohaib, AdventHealth Sebring, Sebring, Florida, United States

Muhammad Sohaib Asghar, MD, MBBS

Group or Team Name

• Chad K. Brands (AdventHealth Sebring Internal Medicine Residency Program).

Background

This study is a comprehensive review of the Centers for Disease Control and Prevention (CDC) National Health and Nutrition Examination (NHANES) databases. The primary objectives were to ascertain patterns of demographic and clinical data among chronic kidney disease (CKD) and dialysis patients.

Methods

This study examines participants from the CDC NHANES database to identify the population diagnosed with chronic kidney disease or dialysis patients in the past 12 months. The total cohort of 51,743 patients were included in each group, i.e., CKD group included 1509 patients (out of which 173 patients have received dialysis in the past 12 months), while non-CKD group included 50,234 patients.d. Exclusion criteria included age >85 years of age (n=624), pregnancy (n=1375), and history of malignancy (n=5575).

Results

The mean age of study participants (n=51,743) was 48.50 ±17.43 years. Age is significantly higher in CKD group but there was no difference in dialysis versus non-dialysis patients (P=0.833). There is no gender predisposition in CKD patients however, males were more likely to undergo dialysis with 13.3% vs 9.8% in females (P=0.032). Among racial differences, Non-hispanic whites are predominantly affected by CKD (37.0%) followed by non-hispanic blacks (29.3%) but non-hispanic blacks are mostly undergoing dialysis (48.6% vs 17.3%). BMI (kg/m²) was significantly higher in CKD group (P<0.001), but lower in dialysis group (P=0.039). Among urinary complaints, history of kidney stones is prevalent in CKD patients (7.7% vs 2.6%, P<0.001). Frequent coexisting comorbidities were congestive heart failure (OR: 9.8), diabetes (OR: 5.4), Coronary artery disease (OR: 5.0), and hypertension (OR: 4.7). UACR (>30 mg/g) is able to categorize CKD patients (AUC: 0.73), at a sensitivity of 44.9% and a specificity of 88.8%.

Conclusion

Certain clinical factors were identified as highly associated with CKD, as disseminated by the NHANES database findings.