Abstract: FR-PO1068
Association of Appetite, Oral Frailty, and Oral Health-Related Self-Efficacy with Kidney Replacement Therapy
Session Information
- Kidney Nutrition and Metabolism
October 25, 2024 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Health Maintenance, Nutrition, and Metabolism
- 1500 Health Maintenance, Nutrition, and Metabolism
Authors
- Kosaka, Shiho, Toho Daigaku, Ota-ku, Tokyo, Japan
- Ohara, Yuki, Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan
- Yanishi, Masaaki, Kansai Ika Daigaku, Hirakata, Osaka, Japan
- Hatta, Tsuguru, Hatta Naika Clinic, Kyoto, Japan
- Hamada, Masami, Josai Kokusai Daigaku, Togane, Chiba, Japan
Background
Patients with hemodialysis (HD) have a high risk of xerostomia and periodontal disease and an increased likelihood of developing gingival hyperplasia after kidney transplantation (KTX) owing to their use of immunosuppressive drugs. However, we are not aware of published studies on the association of oral frailty status and appetite with kidney replacement therapy.
To examine the association between appetite, oral frailty, and oral health-related self-efficacy (OSE) in patients with HD and KTX recipients.
Methods
The following were investigated in patients with HD and KTX recipients by using a questionnaire: demographics (age, sex, height, weight, blood test results, blood pressure, and number of teeth), appetite (CNAQ-J), oral frailty (Oral Frailty Checklist), and OSE (OSE Scale). We statistically analyzed participants after allocating them to two groups: low and high risk for oral frailty. We used χ-squared tests for categorical variables, t-tests for normally distributed continuous variables, Wilcoxon rank-sum tests for non-normally distributed continuous variables, and multiple and logistic regression analysis to examine related factors. This study was approved by the Ethics Committee.
Results
Sixty-one patients with HD and 42 KTX recipients were included in this study. Appetite (HD, 28.9±47.4 vs. KTX, 30.5±3.2; p=0.021) and oral frailty (HD, 3.5±5.7 vs. KTX, 2.39±2.0; p=0.022) scores were both significantly better in KTX recipients, but no significant differences were observed in OSE between the groups. Multivariate analysis revealed that the incidence of oral frailty was 73% lower among KTX recipients (odds ratio [OR], 0.27; 95% confidence interval [CI], 0.11 to 0.62) than that among patients undergoing HD, but the incidence was not significantly different when adjusted for age and sex (adjusted OR, 0.53; 95% CI, 0.18 to 1.52).
Conclusion
In this study, appetite was better and oral frailty was lower among KTX recipients than those among patients with HD. However, whether kidney transplantation has a positive impact on oral frailty and appetite compared to dialysis is difficult to determine, because KTX recipients were significantly younger, and multivariate analysis revealed no significant differences. Longitudinal studies with age- and sex-matching should be performed to determine whether such associations exist.
Funding
- Government Support – Non-U.S.