Abstract: FR-PO381
Prevalence of Cardiovascular Kidney Metabolic Syndrome among US Hispanic/Latino Participants in the Hispanic Community Health Study/Study of Latinos, 2008-2011
Session Information
- Hypertension, CVD, and the Kidneys: Epidemiology
October 25, 2024 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Hypertension and CVD
- 1602 Hypertension and CVD: Clinical
Authors
- Chakrabarti, Amit Kumar, University of Miami Miller School of Medicine, Miami, Florida, United States
- Kondeti, Pooja, University of Miami Miller School of Medicine, Miami, Florida, United States
- Mesa, Robert A., University of Miami Miller School of Medicine, Miami, Florida, United States
- Drexler, Yelena, University of Miami Miller School of Medicine, Miami, Florida, United States
- Tremblay, Julien, University of Miami Miller School of Medicine, Miami, Florida, United States
- Gallo, Linda C., San Diego State University, San Diego, California, United States
- Lash, James P., University of Illinois Chicago, Chicago, Illinois, United States
- Rosas, Sylvia E., Joslin Diabetes Center, Boston, Massachusetts, United States
- Franceschini, Nora, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States
- Massera, Daniele, NYU Langone Health, New York, New York, United States
- Martinez, Claudia, University of Miami Miller School of Medicine, Miami, Florida, United States
- Daviglus, Martha L., University of Illinois Chicago, Chicago, Illinois, United States
- Allison, Matthew, University of California San Diego Department of Medicine, La Jolla, California, United States
- Elfassy, Tali, University of Miami Miller School of Medicine, Miami, Florida, United States
Background
Cardiovascular-Kidney-Metabolic (CKM) syndrome is a staging system that describes the clustering of risk factors and clinical progression of disease at the intersection of metabolic disorders, chronic kidney disease (CKD), and cardiovascular disease (CVD). We described the distribution of CKM stage among diverse US Hispanic/Latino adults.
Methods
The Hispanic Community Health Study/Study of Latinos (HCHS/SOL) is a population-based cohort of Hispanics/Latino adults aged 18-74 years from four US communities. During a comprehensive in person examination (2008-2011), information was collected on: body mass index, waist circumference, glucose tolerance, lipids, blood pressure, metabolic syndrome, CKD, 10-year CVD risk (to define sub-clinical CVD), and self-reported CVD. Participants were classified into four stages of CKM based on American Heart Association definitions: Stage 0 (no risk factors), Stage 1 (excess/dysfunctional adipose tissue), Stage 2 (metabolic risk factors and CKD), Stage 3 (subclinical CVD in CKM syndrome), and Stage 4 (clinical CVD in CKM syndrome). We estimated the age-standardized prevalence of CKM stage by sex and Hispanic/Latino background. All analyses accounted for the HCHS/SOL complex survey design.
Results
Among the 15,832 participants with complete information, mean age was 41.1 years and 52.3% were female. Overall, 10.9% (SE: 0.4) of participants were in CKM stage 0, 27.7% (SE: 0.6) were in stage 1, 53.4% (SE: 0.6) were in stage 2, 2.5% (SE: 0.2) were in stage 3, and 5.5% (SE: 0.3) were in stage 4. CKM stage differed by sex and Hispanic/Latino background group (Figure, chi-square p values <0.05).
Conclusion
Among diverse US Hispanics/Latinos adults, an absence of CKM risk factors was only observed in roughly one in ten adults, while roughly eight in ten adults had evidence of some cardiometabolic dysfunction.
Funding
- NIDDK Support