Kidney Week

Abstract: TH-PO1011

Comorbidity Prevalence among Patients with CKD: Insights from the National Health and Nutrition Examination Survey (NHANES)

Session Information

• CKD: Epidemiology, Risk Factors, and Prevention - 1
  October 24, 2024 | Location: Exhibit Hall, Convention Center
  Abstract Time: 10:00 AM - 12:00 PM

Category: CKD (Non-Dialysis)

• 2301 CKD (Non-Dialysis): Epidemiology, Risk Factors, and Prevention

Authors

• Fuertinger, Doris H., Fresenius Medical Care Deutschland GmbH, Bad Homburg, Hessen, Germany

Doris H. Fuertinger, PhD

• Joerg, David J., Fresenius Medical Care Deutschland GmbH, Bad Homburg, Hessen, Germany

David J. Joerg, PhD

• Meigel, Felix J., Fresenius Medical Care Deutschland GmbH, Bad Homburg, Hessen, Germany

Felix J. Meigel, PhD

• Kotanko, Peter, Renal Research Institute, New York, New York, United States

Peter Kotanko, MD, FASN

Background

In the past decade, obesity and various other conditions that can cause chronic kidney disease (CKD) were on the rise. We used data from the National Health and Nutrition Examination Survey (NHANES) cycles 2007-2008 and 2017-2018 to quantitate the changes in diabetes mellitus (DM), overweight, obesity and heart failure (HF) in different CKD risk categories.

Methods

We stratify the NHANES population into KDIGO risk categories based on albuminuria and creatinine measurements (both serum and urine). Additionally, we assess the prevalence of obesity, HF, and DM by stratifying the NHANES population by body mass index (overweight: BMI 25-30, obesity: BMI >30 kg/m²), self-reported diagnosis of DM as well as fasting glucose or HbA1c levels and HF. We analyze patients for whom complete information on CKD and DM, obesity, and HF was reported.

Results

The percentage of CKD patients that are overweight has slightly declined for all CKD risk categories during the considered decade 2007/2008-2017/2018 (very high risk: 30% to 29%). This is contrasted by a pronounced increase in obesity over all CKD risk categories (very high risk: 43% to 54%), see Fig. 1. The proportion of CKD patients having DM markedly increased in the very high risk group (46% to 57%), but showed only a slight increase in the high risk category (40% to 42%). HF among CKD patients showed a stagnant or declining trend in the high risk categories (13% to 13% and 24% to 20%).

Conclusion

NHANES data suggest a pronounced upward trend in the proportion of CKD patients suffering from DM and obesity and a stagnant trend in CKD patients suffering from HF and overweight. The analysis is limited by the fact that CKD measurements and self-reported diagnoses are not available for all NHANES participants.

Funding

• Commercial Support – Fresenius Medical Care