Kidney Week

Abstract: TH-PO964

Sleep Quality and Symptom Experience in CKD

Session Information

• Physical Activity and Lifestyle in Kidney Diseases
  October 24, 2024 | Location: Exhibit Hall, Convention Center
  Abstract Time: 10:00 AM - 12:00 PM

Category: Health Maintenance, Nutrition, and Metabolism

• 1500 Health Maintenance, Nutrition, and Metabolism

Authors

• Billany, Roseanne E., University of Leicester College of Life Sciences, Leicester, United Kingdom

Roseanne E. Billany, PhD

• Ford, Ella C., Leeds Beckett University, Leeds, United Kingdom

Ella C. Ford

• Sohansoha, Gurneet Kaur, University of Leicester College of Life Sciences, Leicester, United Kingdom

Gurneet Kaur Sohansoha

• Lightfoot, Courtney Jane, University of Leicester College of Life Sciences, Leicester, United Kingdom

Courtney Jane Lightfoot, PhD

• Smith, Alice C., University of Leicester College of Life Sciences, Leicester, United Kingdom

Alice C. Smith, MSc, PhD

Background

Poor sleep quality is common in chronic kidney disease (CKD). Understanding how symptoms (Sx) relate to sleep could help identify people who experience, or are at risk of experiencing, poor sleep quality. We explored the relationship between sleep quality and Sx experienced in people with living with CKD and their significant others (SO).

Methods

People living with CKD and their SO were invited from nine hospital sites in England to complete an online survey including the Pittsburgh Sleep Quality Index (PSQI) and the Kidney Symptom Questionnaire (KSQ). Data were analysed using multiple regression (adjusted for age and sex), χ², and Mann-Whitney U as appropriate.

Results

291 CKD (age 60±14 years; 54% male; 173 (59%) non-dialysis; 66 (23%) kidney transplant; 52 (18%) dialysis [haemo and peritoneal]), and 47 SO (age 63±11 years; 32% male) had complete data. The proportion of participants with poor sleep was greater in CKD than in SO (60% vs 45%, respectively; p=.046). The median number of Sx experienced by people with CKD was higher than in SO (5 vs 2; p=.001). There was a significant association between sleep quality and number of Sx in CKD in univariate analysis and after adjustment (both p<.001). In a multivariable model, loss of appetite, pain, weakness, restless legs syndrome, and feeling cold were significantly associated with poorer sleep quality (Table 1).

Conclusion

We found relationships between experiencing CKD-related Sx and poorer sleep quality in CKD. Optimal CKD management should include assessment of both Sx burden and sleep quality; a bi-directional relationship is likely. Multi-disciplinary teams and sleep services should work together to provide relevant information, and/or referrals to optimise sleep and Sx management and improve quality of life.