Abstract: SA-PO023
Clinical and Cost-Effectiveness of a 6-Month Digital Health Intervention to Improve Physical Activity and Mental Health-Related Quality of Life in People with CKD (Kidney BEAM)
Session Information
- Augmented Intelligence, Large Language Models, and Digital Health
October 26, 2024 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Augmented Intelligence, Digital Health, and Data Science
- 300 Augmented Intelligence, Digital Health, and Data Science
Authors
- Greenwood, Sharlene A., King's College Hospital, London, United Kingdom
- Campbell, Jackie, University of Northampton, Northampton, United Kingdom
- Cooper, Nicola, University of Leicester, Leicester, United Kingdom
- Walklin, Christy Gareth, King's College Hospital, London, London, United Kingdom
- Young, Hannah Ml, University of Leicester, Leicester, United Kingdom
- Castle, Ellen M., Curtin University, Perth, Western Australia, Australia
- Billany, Roseanne E., University of Leicester, Leicester, United Kingdom
- Macdonald, Jamie Hugo, Bangor University, Bangor, United Kingdom
Group or Team Name
- Kidney Beam.
Background
There is inequity in provision of physical rehabilitation services for people living with chronic kidney disease (CKD). The Kidney BEAM trial evaluated the clinical value and cost effectiveness of a physical activity digital health intervention in CKD. We hypothesised that the Kidney Beam intervention would be a cost-effective solution to improve mental health-related quality of life (HRQOL) for people with CKD.
Methods
In a single-blind, 11 centre, randomised controlled trial, 340 adult participants with CKD were randomly assigned to either the Kidney BEAM physical activity digital health intervention or a waitlist control. This study assesses the difference in the Kidney Disease Quality of Life Short Form 1.3 Mental Component Summary (KDQoL-SF1.3 MCS) between intervention and control groups at 6 months, and cost-effectiveness of the intervention.
Results
At 6 months there was a significant difference in mean adjusted change in KDQoL MCS score between Kidney BEAM and waitlist control (intention-to-treat adjusted mean: 5.9 {95% confidence interval: 4.4 to 7.5} arbitrary units, p<0.0001), and a significant increment in quality-adjusted life years (QALYs) of 0.027 {95% confidence interval: 0.013 to 0.040} years per participant, resulting in a cost per QALY of £3,446 for the Kidney BEAM intervention, and a 93% and 98% probability of the intervention being cost-effective at a willingness to pay threshold of £20,000 and £30,000 per quality-adjusted life year gained.
Conclusion
The Kidney BEAM physical activity digital health intervention is a clinically valuable and cost-effective means to improve mental health related quality of life in people with CKD.