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Abstract: PUB227

Identifying Global Awareness of SGLT2 Inhibitors through Google Search Trend Analysis

Session Information

Category: Diversity and Equity in Kidney Health

  • 900 Diversity and Equity in Kidney Health

Authors

  • Fichadiya, Harshil, Mayo Clinic Minnesota, Rochester, Minnesota, United States
  • Patel, Vraj, Canton Medical Education Foundation, Canton, Ohio, United States
  • Cheungpasitporn, Wisit, Mayo Clinic Minnesota, Rochester, Minnesota, United States
  • Craici, Iasmina, Mayo Clinic Minnesota, Rochester, Minnesota, United States
Background

SGLT-2i has been identified as therapy with profound benefit in disease involving multiple organs. Initially introduced as anti-hyperglycemic drugs, they are now used for heart failure, proteinuric and early stages of non-proteinuric CKD, hyponatremia, hypomagnesemia. We performed a google trend analysis of SGLT2i related google search since 2004 and assessed the trend of this search overtime in different areas of the World. This may be an indirect measure of public awareness, availability, and utility of these medicines in different regions globally

Methods

A retrospective analysis of Google Trends was conducted for the term “SGLT-2 inhibitors” from 2004 until April 30, 2024. Search trends were assessed over time as well as per nation.

Results

A sustained rise is seen in the search trends for SGLT2i since Jan 2017 with this trend continuing to rise exponentially due to recent trials determining its benefit. The number of google searches per region have been distributed in different shades of blue with the darkest shade representing region with the highest number of searches and the lightest shade representing region with the lowest number in Fig 1. Grey represents areas with lack of enough data for the term. Highest search rates were seen in Japan, Taiwan, Hong Kong and lowest search rates were seen in Russia, China, some eastern European and South American countries. Certain areas in Central Asia, Africa, Middle east and South America did not have enough data to compute a search number.

Conclusion

Google trends are an indirect indicator of public awareness and use of SGLT-2i, given the recently identified multisystem benefit of SGLT-2i, it is important to assess the discrepancy in awareness and distribution of these drugs. Areas with lower awareness can be identified with the distribution map in Fig 1 and targeted efforts to increase awareness about kidney disease and benefit of SGLT-2i should be focused on these areas from a global health perspective. Major contributing factors to low awarness are socioeconomic disparities, unequal market distribution & lack of internet and medical literature access & efforts to mitigate these should be made to ensure equity in global health.