Abstract: PUB129
Determination of Fracture Risk in a Hemodialysis Unit in Ecuador Using the FRAX Tool without Bone Mineral Density (BMD)
Session Information
Category: Dialysis
- 801 Dialysis: Hemodialysis and Frequent Dialysis
Authors
- Navarro, Ana Yadira, Fresenius Medical Care, Quito, Ecuador
- Perez, Ailiyomar, Menydial, Ambato, Chimborazo, Ecuador
- Lino, Ricardo J., Baxter Ecuador SA, Quito, Pichincha, Ecuador
Background
Patients with chronic kidney disease (CKD) present mineral bone disease which is developing
from earlier stages, producing osteoporotic fractures that aggravate their morbidity and mortality during the
treatment, so prevention plays a fundamental role in preserving the quality of life of patients.
Methods
cross-sectional, correlational and descriptive study. It included 209 patients. As inclusion criterion: patients between 40 and 90 years old, on hemodialysis. Excluded were: patients with malignant disease, bedridden patients and patients receiving antiresorptive treatments. Demographic variables and serum levels of biochemical markers that guide the diagnosis of bone mineral disease were evaluated.
cross-sectional, correlational and descriptive study. It included 209 patients. As inclusion criterion: patients between 40 and 90 years old, on hemodialysis. Excluded were: patients with malignant disease, bedridden patients and patients receiving antiresorptive treatments. Demographic variables and serum levels of biochemical markers that guide the diagnosis of bone mineral disease were evaluated.
Results
60.28% men and 39.71% women, with an average age of 61.85±10.75. 77.55% were at risk of major osteoporotic fracture, of which 43.75% were women and 56.24% men, with an average age of 64.78±9.88. Differentiating the higher risk group vs. the lowest risk was recorded: BMI 24.53vs 25.98; calcium 8.26 vs 8.4; Pth 385.91 vs 359.2; in albumin and phosphorus there were no significant differences. The variables resulted with sensitivity and specificity of 95% confidence. In hip fracture, 27.27% of patients were at risk, of which 49.12% were women and 58.87% were men, with an average age of 71.73±8.89; BMI, calcium and albumin were lower than in those patients without significant risk of hip fracture, respectively, 23.64 vs 25.30; 8 vs 8.25; 3.72 vs 3.88; the opposite occurred with Pth 434 vs 358.92; which is expected, again the phosphorus without relevant meanings and the confidence index for the significant variables was 95% for sensitivity and specificity
Conclusion
The risk of major osteoporotic fracture and hip fracture in the hemodialysis unit was high. The frax tool proved to be assertive for patients on hemodialysis, even without the use of BMD, the results show the association of variables that allow diagnosing mineral disease.