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Kidney Week

Abstract: SA-PO1135

Optimizing Patient Outcomes in Advanced CKD: Insights from Predialysis Care in Qatar

Session Information

Category: CKD (Non-Dialysis)

  • 2302 CKD (Non-Dialysis): Clinical, Outcomes, and Trials

Authors

  • Ghonimi, Tarek Abdellatif, Hamad Medical Corporation, Doha, Ad Dawhah, Qatar
  • Hamad, Abdullah Ibrahim, Hamad Medical Corporation, Doha, Ad Dawhah, Qatar
  • Fouda, Tarek Ahmed Elsayed, Hamad Medical Corporation, Doha, Ad Dawhah, Qatar
  • Ismail, Hany Ezzat Abdelaziz, Hamad Medical Corporation, Doha, Ad Dawhah, Qatar
  • Ahmad, Farooq, Hamad Medical Corporation, Doha, Ad Dawhah, Qatar
  • Baig, Muhammad Abdul Azim, Hamad Medical Corporation, Doha, Ad Dawhah, Qatar
  • Abdellatif, Mohamed Tarek, Misr University for Science and Technology College of Medicine, 6th of October City, Giza, Egypt
  • Ateya, Heba Mohamed, Hamad Medical Corporation, Doha, Ad Dawhah, Qatar
  • Mathew, Mincy, Hamad Medical Corporation, Doha, Ad Dawhah, Qatar
  • Tolba, Hoda, Hamad Medical Corporation, Doha, Ad Dawhah, Qatar
  • Al-Ali, Fadwa S., Hamad Medical Corporation, Doha, Ad Dawhah, Qatar
  • Al-Malki, Hassan A., Hamad Medical Corporation, Doha, Ad Dawhah, Qatar
Background

A pre-dialysis multidisciplinary clinic (MDC) program improves the quality of care for advanced CKD patients. This study assesses the impact of such a program on the quality of CKD patients outcomes.

Methods

This report outlines the first-year findings of a three-year prospective study initiated on December 5, 2022, at Hamad General Hospital. We enrolled 695 patients with advanced CKD from multidisciplinary Low Clearance Clinics and analyzed demographic and laboratory data retrieved from electronic health records.

Results

Among 695 study patients, initial eGFR was 15.7 ± 5.4 mL/min/1.73m2, decreasing to 14.9 ± 6.7 mL/min/1.73m2 at study initiation. 39% had eGFR < 15 mL/min/1.73m2 at referral. 43.7% received dialysis education, and 43% were referred for transplant evaluation. During follow-up, 24.3% started dialysis (55% acutely, 45% electively). Predictors for acute dialysis were low HB, low eGFR, and high urea (odds 0.662, 1.306, 1.101 respectively). Late referral (eGFR < 15 mL/min/1.73m2) correlated with shorter time to dialysis (log rank value = 0.004). Mean eGFR at dialysis initiation was 6.3 ± 3.6mL/min/1.73m2. Hemodialysis (73.3%) was primary, with temporary lines (36.6%) and AVF (28.4%) common. 2.4% had preemptive renal transplant, and mortality rate during follow-up was 1.7%.

Conclusion

Multidisciplinary pre-dialysis care is crucial for advanced CKD management and transitioning to kidney replacement therapy. This report emphasizes its role in enhancing outcomes, stressing early referral for interventions like dialysis education and transplant evaluation to optimize CKD care.

Funding

  • Private Foundation Support