Kidney Week

Abstract: FR-PO512

Incidence and Determinants of Primary Arteriovenous Access Failure in Dialysis Patients: A Qatar-Based Retrospective Analysis

Session Information

• Dialysis Vascular Access
  October 25, 2024 | Location: Exhibit Hall, Convention Center
  Abstract Time: 10:00 AM - 12:00 PM

Category: Dialysis

• 803 Dialysis: Vascular Access

Authors

• Ghonimi, Tarek Abdellatif, Hamad Medical Corporation, Doha, Ad Dawhah, Qatar

Tarek Abdellatif Ghonimi, MBBS, MD, FASN

• Hamad, Abdullah Ibrahim, Hamad Medical Corporation, Doha, Ad Dawhah, Qatar

Abdullah Ibrahim Hamad, MD, FASN

• Elgaali, Musab, Hamad Medical Corporation, Doha, Ad Dawhah, Qatar

Musab Elgaali, MD

• Ali, Mohamed Yousif Mohamed Salih, Hamad Medical Corporation, Doha, Ad Dawhah, Qatar

Mohamed Yousif Mohamed Salih Ali, MBBS

• Abdellatif, Mohamed Tarek, Misr University for Science and Technology, 6th of October City, Giza, Egypt

Mohamed Tarek Abdellatif, MS

• Alomari, Anees Jamil, Hamad Medical Corporation, Doha, Ad Dawhah, Qatar

Anees Jamil Alomari, RN

• Ibrahim, Athar Ibrahim Hassan, Hamad Medical Corporation, Doha, Ad Dawhah, Qatar

Athar Ibrahim Hassan Ibrahim, RN

• Ibrahim, Rania Abdelaziz, Hamad Medical Corporation, Doha, Ad Dawhah, Qatar

Rania Abdelaziz Ibrahim, RN

• Al-Malki, Hassan A., Hamad Medical Corporation, Doha, Ad Dawhah, Qatar

Hassan A. Al-Malki, MD

Background

The demand for hemodialysis (HD) among patients with end-stage kidney disease (ESKD) is increasing globally. A well-functioning Arterio-vascular access (AV) is crucial for effective HD therapy. This study aimed to determine the incidence and risk factors associated with primary AV access failure in HD patients.

Methods

This retrospective study included HD patients who underwent AV access creation between 01/01/2021 and 31/12/2023 in Qatar's dialysis centers. Data were obtained from electronic health records , including demographics, medical comorbidities, VA types, time to maturation, and incident of primary AV access failure.

Results

A total of 242 AV accsess creations were included. The incidence of primary AV Access failure was 28%. It was highly significant in patients with Left radio cephalic arterio-veinous fistula ( in 32.3%). Significant associations were found between primary AV access failure and older age (p < 0.001), diabetes (p = 0.027), atherosclerosis (p = 0.019) and lower systolic and diastolic blood pressure (P <0.016 and < 0.0001 respectively). However, statin use showed significant reduction in primary AV access failure (p = 0.001). Multivariate analysis identified older age, diabetes, atherosclerosis and lower systolic BP as significant risk factors for AV access failure, while statin use was associated with a reduced risk (odds ratio 0.167, 95% CI 0.080-0.347, p < 0.0001).

Conclusion

Primary VA failure in HD patients is notable, with older age, diabetes, and atherosclerosis as significant risk factors. Interestingly, statin use is linked to lower risk of primary AV access failure, emphasizing the need for early risk factor identification and management to improve AV access outcomes in HD patients.

Funding

• Private Foundation Support