Abstract: TH-PO235
Adequate Convective Volume Can Be Achieved in Majority of Multiethnic Asian Patients Receiving Hemodiafiltration in Singapore
Session Information
- Hemodialysis, Hemodiafiltration, and Frequent Dialysis
October 24, 2024 | Location: Exhibit Hall, Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 801 Dialysis: Hemodialysis and Frequent Dialysis
Authors
- Chan, Cindy, Fresenius Medical Care Asia Pacific Ltd, Hong Kong, Hong Kong
- Zhang, Yan, Fresenius Medical Care Deutschland GmbH, Bad Homburg, Hessen, Germany
- Cheung, Yan Yi, Fresenius Medical Care Asia Pacific Ltd, Singapore, Singapore
- Mooppil, Nandakumar, Fresenius Medical Care Asia Pacific Ltd, Singapore, Singapore
- Singh, Tripti, Fresenius Medical Care Asia Pacific Ltd, Singapore, Singapore
- Winter, Anke, Fresenius Medical Care Deutschland GmbH, Bad Homburg, Hessen, Germany
- Maddux, Franklin W., Fresenius Medical Care Holdings Inc, Waltham, Massachusetts, United States
- Hymes, Jeffrey L., Fresenius Medical Care Holdings Inc, Waltham, Massachusetts, United States
- Nikam, Milind, Fresenius Medical Care Asia Pacific Ltd, Singapore, Singapore
Background
High volume hemodiafiltration (HDF) has been shown to improve patient outcomes. However, there is a very common concern amongst healthcare practitioners about the feasibility of achieving optimal convective volume (CV) in Asian patients.
Methods
A 5-year retrospective cohort analysis was conducted on patients dialyzing at Fresenius Kidney Care clinics in Singapore from 2019 to 2023, aiming to evaluate HDF practice patterns and outcomes. We adjusted the CV to body surface area (BSA) as has been suggested by some publications.
Results
A total of 1404 patients received 291,822 HDF sessions during the study period. At baseline, the cohort's mean age was 64 (±13) years and it was followed up for 34 (±17) months on average, with 60% males. The majority were Chinese (51%), followed by Malay (11%) and Indian (4%) patients.
The most common modality was post-dilutional HDF (70%) followed by pre-dilutional in 25% cases. In 5% cases the modality was not recorded. The CVs achieved in various sub-groups in this cohort are listed in Table 1.
Conclusion
Contrary to the common belief, adequate CVs can be achieved in majority of Asian patients. With growing interest and experience of HDF, this is likely to improve further. Of note, Malay patients had lower CV compared to those of Chinese and Indian ethnicity – a further study of patient and practice related factors in Asian geographies on CV achievement is warranted.
Funding
- Commercial Support – Fresenius Medical Care