Kidney Week

Abstract: TH-PO852

Association and Contribution of Gender-Related Characteristics to Prevalence of CKD in Women and Men in a Multiethnic Population

Session Information

• Race, Ethnicity, and Gender in Kidney Health and Care
  October 24, 2024 | Location: Exhibit Hall, Convention Center
  Abstract Time: 10:00 AM - 12:00 PM

Category: Diversity and Equity in Kidney Health

• 900 Diversity and Equity in Kidney Health

Authors

• Vosters, Taryn G., Amsterdam UMC Locatie AMC, Amsterdam, Noord-Holland, Netherlands

Taryn G. Vosters, MS, MSc

• Stel, Vianda S., Amsterdam UMC Locatie AMC, Amsterdam, Noord-Holland, Netherlands

Vianda S. Stel, PhD

• Vogt, Liffert, Amsterdam UMC Locatie AMC, Amsterdam, Noord-Holland, Netherlands

Liffert Vogt, MD, PhD

• Jager, Kitty J., Amsterdam UMC Locatie AMC, Amsterdam, Noord-Holland, Netherlands

Kitty J. Jager, MD, PhD

• van Ittersum, Frans J., Amsterdam UMC Locatie VUmc, Amsterdam, Noord-Holland, Netherlands

Frans J. van Ittersum, MD, PhD

• Van den Born, Bert-Jan, Amsterdam UMC Locatie AMC, Amsterdam, Noord-Holland, Netherlands

Bert-Jan Van den Born, MD, PhD

• van Valkengoed, Irene, Amsterdam UMC Locatie AMC, Amsterdam, Noord-Holland, Netherlands

Irene van Valkengoed

Background

In chronic kidney disease (CKD), prevalence differences between sexes have been reported. While biological factors have been investigated, research on sociocultural factors is scarce. We explore the extent gender-related characteristics associate with, and contribute to, CKD prevalence in women and men in a multi-ethnic population.

Methods

Cross-sectional analyses were performed on data of 12,221 women and 8,930 men aged 18-70 years across six ethnic groups from the HELIUS Study. Using age-, education-, and ethnicity adjusted Poisson regression, we determined associations between time spent on housework; primary earner status; employment status; and occupational segregation, and CKD. Population Attributable Fractions estimated the contribution to CKD and the extent traditional CKD risk factors explained these contributions.

Results

In women, associations with CKD were found for doing little housework, part-time work, and unemployment. In men, primary-earnership and unemployment were associated. Associations aligned across ethnic groups. Estimated contributions ranged from 1.8% for women doing little housework to 26.5% for part-time employment and 12.1% for unemployment to 37.5% for primary-earnership in men, and were hardly explained by risk factors.

Conclusion

In our study, gender-related characteristics are associated with CKD in women and men across ethnic groups. Contributions to population prevalence may hardly be explained by CKD risk factors.

Funding

• Private Foundation Support