Kidney Week

Basic/Clinical Science Session

Podocyte Mechanosignaling in Health and Disease: Putting Their Feet Down

October 25, 2024 | 02:00 PM - 04:00 PM

Location: Room 1, Convention Center

Session Description

This session highlights new insights into the mechanisms of podocyte mechanotransduction and considers emerging therapeutic opportunities.

Learning Objective(s)

• Explain the role of mechanosignaling in establishing and maintaining podocyte identity
• Discuss new technologies that allow for characterization of podocyte interactions with the basement membrane in health and disease
• Describe podocyte mechanosignaling as a potential therapeutic target in proteinuric kidney diseases

Learning Pathway(s)

• Glomerular Diseases
• Genetic Diseases and Development

Moderators

• Tarak Srivastava, MD, FASN
• Hani Suleiman, MD, PhD

Presentations

• Stressed Out: Unraveling the Mechanisms of Podocyte Mechanosignaling
  02:00 PM - 02:30 PM
  
  • Nicole Endlich, PhD

Stressed Out: Unraveling the Mechanisms of Podocyte Mechanosignaling

October 25, 2024 | 02:00 PM - 02:30 PM

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• Holding Tight: Measurement of Podocyte Force Development Using Elastic Resonator Interference Stress Microscopy
  02:30 PM - 03:00 PM
  
  • Malte C. Gather, PhD

Holding Tight: Measurement of Podocyte Force Development Using Elastic Resonator Interference Stress Microscopy

October 25, 2024 | 02:30 PM - 03:00 PM

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• Standing in the GAP: Exploring the Role of ARHGAP29 in YAP-Mediated Mechanosignaling in Podocytes
  03:00 PM - 03:30 PM
  
  • Christoph Schell, MD, PhD

Standing in the GAP: Exploring the Role of ARHGAP29 in YAP-Mediated Mechanosignaling in Podocytes

October 25, 2024 | 03:00 PM - 03:30 PM

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• Standing Firm: Considering the Therapeutic Potential of Targeting Podocyte Mechanosignaling
  03:30 PM - 04:00 PM
  
  • Markus M. Rinschen, MD

Standing Firm: Considering the Therapeutic Potential of Targeting Podocyte Mechanosignaling

October 25, 2024 | 03:30 PM - 04:00 PM

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