Kidney Week

Basic/Clinical Science Session

Podocyte Mechanosignaling in Health and Disease: Putting Their Feet Down

October 25, 2024 | 02:00 PM - 04:00 PM

Location: Room 1, Convention Center

Session Description

This session highlights new insights into the mechanisms of podocyte mechanotransduction and considers emerging therapeutic opportunities.

Support is provided by an educational grant from Travere Therapeutics, Inc.

Learning Objective(s)

• Explain the role of mechanosignaling in establishing and maintaining podocyte identity
• Discuss new technologies that allow for characterization of podocyte interactions with the basement membrane in health and disease
• Describe podocyte mechanosignaling as a potential therapeutic target in proteinuric kidney diseases

Learning Pathway(s)

• Glomerular Diseases
• Genetic Diseases and Development

Moderators

• Tarak Srivastava, MD, FASN
• Hani Suleiman, MD, PhD

Presentations

• Stressed Out: Unraveling the Mechanisms of Podocyte Mechanosignaling
  02:00 PM - 02:30 PM
  
  • Nicole Endlich, PhD

Stressed Out: Unraveling the Mechanisms of Podocyte Mechanosignaling

October 25, 2024 | 02:00 PM - 02:30 PM

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• Holding Tight: Measurement of Podocyte Force Development Using Elastic Resonator Interference Stress Microscopy
  02:30 PM - 03:00 PM
  
  • Malte C. Gather, PhD

Holding Tight: Measurement of Podocyte Force Development Using Elastic Resonator Interference Stress Microscopy

October 25, 2024 | 02:30 PM - 03:00 PM

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• Standing in the GAP: Exploring the Role of ARHGAP29 in YAP-Mediated Mechanosignaling in Podocytes
  03:00 PM - 03:30 PM
  
  • Christoph Schell, MD, PhD

Standing in the GAP: Exploring the Role of ARHGAP29 in YAP-Mediated Mechanosignaling in Podocytes

October 25, 2024 | 03:00 PM - 03:30 PM

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• Standing Firm: Considering the Therapeutic Potential of Targeting Podocyte Mechanosignaling
  03:30 PM - 04:00 PM
  
  • Markus M. Rinschen, MD

Standing Firm: Considering the Therapeutic Potential of Targeting Podocyte Mechanosignaling

October 25, 2024 | 03:30 PM - 04:00 PM

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