ASN represents more than 21,000 kidney health professionals working to help people with kidney diseases and their families. Comprised of all of ASN's focus areas, the ASN Alliance for Kidney Health allows the society to continue its growth and work towards the goal of a world without kidney diseases.
The latest Nephrology Self-Assessment Program (nephSAP) issue, Volume 23: Issue 4 (Oct 2024): Chronic Kidney Disease is now available online.
Steroid resistance nephrotic syndrome 23 minutes ago
I welcome any input regarding a case I saw in our clinic of 6 year old girl with Nephrotic syndrome which was diagnosed when she was 2 year old. p...
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RE: Nephrotic Syndrome In A Young Lady 2 hours ago
Young woman with MGN with both mesangial deposits and sub epi deposits? not full house But feels like a class 5 lupus I look forward to whe...
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RE: Nephrotic Syndrome In A Young Lady 2 hours ago
This case raises questions which have remained unanswered for decades. What is the mechanism for a rise in serum albumin concentration independent ...
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RE: Nephrotic Syndrome In A Young Lady 2 hours ago
Then , if nephrotic syndrome persists, RTX is indicated as therapy. ------------------------------ Richard Glassock MD, FASN Laguna Woods CA (...
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RE: Nephrotic Syndrome In A Young Lady 2 hours ago
Unfortunately, staining for NELL , EXT I & II are not available. --------------------------------- Peter Youssef, MSc., MRCP (UK), ESENeph Cairo, ...
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RE: preoperative nephrology evaluation 2 hours ago
I mean like we have for cardiac risk ------------------------------ Sadeem Ali MD Bridgeport WV (612) 865-9067 ------------------------------
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RE: preoperative nephrology evaluation 2 hours ago
This becomes more concern for chronic kidney disease, Predialysis patients and I always wonder if there is a risk score calculator Something like w...
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preoperative nephrology evaluation 2 hours ago
We are getting a nephrology consult for evaluation of 77 age patient with ESRD (He is on hemodialysis via AV fistula 3 days a week outpatient since...
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RE: Nephrotic Syndrome In A Young Lady 3 hours ago
I will go out on theoretical limb. Steroids initially drop lymphoyctic count and we see that after starting high therapy. Not sure they can deplete...
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RE: Nephrotic Syndrome In A Young Lady 4 hours ago
I suppose that it is theoretically possible that the patient has two diseases concurrently (non-PLA2R Primary MN and an auto-antibody mediated diff...
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RE: Nephrotic Syndrome In A Young Lady 4 hours ago
Dr. Glassock: I agree with you that prednisone alone is unlikely to be effective in MN. Since SAlb has improved from 19 g/L to 32 g/L on prednisone...
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RE: ATI, Anuria post kidney transplant 4 hours ago
Another problem with mTOR-inhibitor use is the possibility of confounding proteinuria from FSGS/collapsing glomerulopathy that can be caused by thi...
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RE: ATI, Anuria post kidney transplant 5 hours ago
Dr. Emara: can you please post the actual UPr (mg/dl) and UCr (mg/dl). values from which UPCR of 2.2 g/g was calculated. Also, was that urine sampl...
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RE: ATI, Anuria post kidney transplant 5 hours ago
Seems most consistent with recurrent FSGS. I would continue PLEX till you have EM report. Agree with Dr Aledan regarding mTor in early post-op peri...
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RE: Nephrotic Syndrome In A Young Lady 5 hours ago
Steroids alone are generally ineffective for inducing a lasting remission in MN . You should stain for NELL1 (if possible) as it might indicate a m...
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RE: ATI, Anuria post kidney transplant 6 hours ago
Thank you Dr lerman for sharing this case report The difference was that Tac level was low a time of biopsy, so I think tac toxicity is unlikely ...
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RE: ATI, Anuria post kidney transplant 6 hours ago
Yes thus UPCR from a very small amount of urine Less than 100 ml /24h --------------------------------- Ahmed Emara MD, MBChB, FASN Ain shams U...
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RE: Nephrotic Syndrome In A Young Lady 6 hours ago
@Ashraf El-Meanawy Never --------------------------------- Peter Youssef, MSc., MRCP (UK), ESENeph Cairo, Egypt ---------------------------------
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RE: Nephrotic Syndrome In A Young Lady 6 hours ago
Is she on biologic treatment for eczema or asthma? ------------------------------ Ashraf El-Meanawy , MD, MS, PHD, FASN Professor of Medicine Dir...
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RE: Nephrotic Syndrome In A Young Lady 7 hours ago
If there is a rapid and complete disappearance of proteinuria with prednisone, may need to consider a podocytopathy + MN (keeping in mind extensive...
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RE: Nephrotic Syndrome In A Young Lady 7 hours ago
Actually 3 weeks ago , her serum albumin was 19 and she had edema. A full dose prednisolone was initiated in another centre. Currently her serum a...
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RE: Nephrotic Syndrome In A Young Lady 7 hours ago
SAlb level? With proteinuria of 4.5 g (assuming only mild/no hypoalbuminemia and normal renal function), an initial trial of generic antiproteinuri...
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RE: ATI, Anuria post kidney transplant 7 hours ago
Exactly why I inquired about the EM as a diagnosis of Primary de novo or recurrent primary FSGS would not be possible this early after transplant w...
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RE: Nephrotic Syndrome In A Young Lady 7 hours ago
Does she merit rituxmab? --------------------------------- Peter Youssef, MSc., MRCP (UK), ESENeph Cairo, Egypt ---------------------------------
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RE: Nephrotic Syndrome In A Young Lady 8 hours ago
If the mesangial deposits are scanty and the deposits are sub epithelial, thisis compatible wuth a non-PLA2R MN, most likely NELL1 or EXTI/II. --...
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RE: Nephrotic Syndrome In A Young Lady 9 hours ago
@K.K. Venkat That's what we can assume, she didn't mention clearly. --------------------------------- Peter Youssef, MSc., MRCP (UK), ESENeph Ca...
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RE: Nephrotic Syndrome In A Young Lady 9 hours ago
Besides mesangial deposits, were the capillary wall deposits on EM predominantly subepithelial? ------------------------------ K.K. Venkat MD Tro...
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RE: ATI, Anuria post kidney transplant 9 hours ago
"UPCR 2.2 gm/gm ............. UA showed wbcs (10-15) and RBCs (>100)" What was the 24hr urine output on the day these urinary results were obtai...
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Nephrotic Syndrome In A Young Lady 14 hours ago
I am eager to listen to the community opinion regarding this case. A 24 year old lady with a history of vitiligo, eczema and well controlled bronch...
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RE: semaglutide, gfr, proteinuria 17 hours ago
In the SELECT trial 81% of the benefits of GLP1RA as Reno-protective agents were due to weight loss (in a mediation analysis). No weight loss-, no ...
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RE: semaglutide, gfr, proteinuria 18 hours ago
Despite decades of RAASi use, CKD progresses and this is because of different pathways that should be tackled and this is the rational for emerging...
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RE: dsDNA + and GBM + 18 hours ago
If the biopsy shows LN and in particular I was thinking of class V LN given normal complements; this co-occurrence of LN and anti-GBM disease has b...
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RE: semaglutide, gfr, proteinuria 18 hours ago
I am uncomfortable with GLP 1 A in elderly because of muscle wasting . There is already age related muscle wasting . I am aware of all the benefits...
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RE: semaglutide, gfr, proteinuria 19 hours ago
I don’t think that GLP1-RAs are just a weight loss medication and the nephroprotective effects are from this mechanism as many studies showed that ...
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RE: ATI, Anuria post kidney transplant 20 hours ago
Any systemic symptoms? What is the CRP? Sound like UTI, would treat with antibiotics and observe --------------------------------- Hayder Aledan M...
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RE: ATI, Anuria post kidney transplant 20 hours ago
No obvious cause of ATN UA showed wbcs (10-15) and RBCs (>100) --------------------------------- Ahmed Emara MD, MBChB, FASN Ain shams Universi...
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RE: semaglutide, gfr, proteinuria 23 hours ago
SMART trial presented last week at ASN kidney week on use of semaglutide in non diabetic albuminuric CKD has measured Iohexol GFR in 47 participant...
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RE: dsDNA + and GBM + 23 hours ago
Ana negative, normal c3 and c4, renal biopsy pending results. we did 5 plex session until negative gbm and continue Imunosupression. serum crea...
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RE: semaglutide, gfr, proteinuria 1 day ago
I see no reason to conclude that the apparent decline in a Scr levels 3 months after starting GL21RA has anything at all to do with improved GFR. I...
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RE: ATI, Anuria post kidney transplant 1 day ago
The TAC trough levels is so low so I would increase the dose of TAC to a target of 8-10. You know that the use of mTORi in early KT defeat wound he...
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RE: semaglutide, gfr, proteinuria 1 day ago
I have observed benefits with GLP1-RA usually after 3-6 months and approximately 5% weight loss and I agree this may explained by sarcopenia effect...
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RE: Re: pt with resistant HTN 1 day ago
I think we should treat HTN as pathway directed therapy because using multiple drugs may increase AEs and questioned the adherence. So in this youn...
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RE: ATI, Anuria post kidney transplant 1 day ago
UPCR 2.2 gm/gm --------------------------------- Ahmed Emara MD, MBChB, FASN Ain shams University Cairo 00201006721401 ------------------------...
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RE: ATI, Anuria post kidney transplant 1 day ago
Biopsy report --------------------------------- Ahmed Emara MD, MBChB, FASN Ain shams University Cairo 00201006721401 -------------------------...
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RE: ATI, Anuria post kidney transplant 1 day ago
Yes was anuric EM done pending report --------------------------------- Ahmed Emara MD, MBChB, FASN Ain shams University Cairo 00201006721401 ...
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RE: ATI, Anuria post kidney transplant 1 day ago
Was recepient anuric prior to transplant ? Proteinuria? Was EM done on post to biopsy ? ------------------------------ [Mark] [Lerman] [MD,FASN,F...
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RE: Re: pt with resistant HTN 1 day ago
Hello, tough case, I agree with some comments regarding renal denervation and its proposed benefits, with the high pill burden and lack of improvem...
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RE: semaglutide, gfr, proteinuria 1 day ago
Hi, I regularly start my patients on GLP-1, specially if they are diabetic, or even if they are not diabetic but have proteinuria, and even special...
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RE: Case Of Angimyolipoma 1 day ago
Thanks a lot for the paper! Very nicely written, and a good overview! ------------------------------ [Christian] [Rosenberger] MD [] [Charité] [B...
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ATI, Anuria post kidney transplant 1 day ago
Hi every one i need your thoughts regarding this challenging case: 27 y male ESKD (due to 1ry FSGS) underwent living related kidney transplant 2 ...
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