ASN represents more than 21,000 kidney health professionals working to help people with kidney diseases and their families. Comprised of all of ASN's focus areas, the ASN Alliance for Kidney Health allows the society to continue its growth and work towards the goal of a world without kidney diseases.
The latest Nephrology Self-Assessment Program (nephSAP) issue, Volume 23: Issue 4 (Oct 2024): Chronic Kidney Disease is now available online.
RE: Tip variant FSGS 59 minutes ago
Very active maybe proteinuria will stabalize Has anyone had any luck with sglt2i and FSGS I haven't?I think they are less useful than ACEi/aRB bu...
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RE: Pregnancy in Transplant patients with aHUs and on complement inhibitors 1 hour ago
Does she have pathologenic genetic variant ؟؟ Some variants have high risk of relapse others are low risk If no variant detected relapse are minma...
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RE: Tip variant FSGS 1 hour ago
His mother may accept SGLT inhibitor --------------------------------- Alaa Nabih Abdalla nephrology fellow Egypt ------------------------------...
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RE: IgA With ANCA Positivity 3 hours ago
Total glomeruli: 41 Global sclerosis: 13 Segmental sclerosis: 7 --------------------------------- Kinjal Gosalia MD Dix Hills NY (516) 504-5279...
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RE: IgA With ANCA Positivity 3 hours ago
Albumin 3.9. No edema. So no nephrotic syndrome just nephrotic range proteinuria. BMI 39. It could be secondary FSGS from IgA or Obesity --------...
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RE: IgA With ANCA Positivity 3 hours ago
No hydrazine, allopurinol, PTU, methimazole, IVDU --------------------------------- Kinjal Gosalia MD Dix Hills NY (516) 504-5279 --------------...
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RE: IgA With ANCA Positivity 3 hours ago
SAlb level? How much edema? Is "50% glomerulosclerosis" global? How obese is she? If this is a primary podocytopathy would expect significant hypoa...
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RE: Tip variant FSGS 4 hours ago
"Very active fit kid." Some of the fluctuation in proteinuria may be the effect of heavy physical activity increasing it. ---------------------...
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RE: Tip variant FSGS 5 hours ago
Yes I would not treat now at what point would you treat? Nephrotic range probably too late but > 1gm albumin/cr and lower serum albumin thank...
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RE: Pregnancy in Transplant patients with aHUs and on complement inhibitors 5 hours ago
Not much experience with Eculizumab or Ravulizumab in Pregancey Several reports of their use in PNH and Pregnacy and PNH indicate tgat it may be sa...
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RE: IgA With ANCA Positivity 5 hours ago
I would treat with oral systemic prednisone just as you would with a primary Podocytopathy . I do not know what to make of the serology. Has the pa...
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RE: Tip variant FSGS 5 hours ago
With these findings I would just follow the patient with repeat values about every 3 months. ------------------------------ Richard Glassock MD,...
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RE: Tip variant FSGS 6 hours ago
Serum albumin is 4.4 and stable. UPCR 0.6, albumin/cr 338 mg/gm ------------------------------ Kevin Mitchell MD Nephrologist St. Luke?s Medical ...
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RE: IgA With ANCA Positivity 6 hours ago
Thank you Dr. Glassock. Thant’s a great point. I’ll wait for the EM. Would you do do pulse and prednisone or localized such as Tarpeyo? ---------...
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RE: primary Membranous nephropathy and HBV infection 7 hours ago
I would wait several moths after successful therapy of HBV with Entecavir . Follow anti-PLA2R antibody levels, there is a fairly good chance for a ...
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RE: Tip variant FSGS 7 hours ago
What is the serum albumin level? No indication for repeat kidney biopsy. You might want to consider RTX for relapsing steroid sensitive MCD/FSGS. ...
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RE: IgA With ANCA Positivity 8 hours ago
Do you have EM to further characterize the S1 lesion-e.g. - is a diffuse Podocytopathy present. If so, oral systemic steroids are indicted, in my o...
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RE: APOL-1 mediated kidney disease 8 hours ago
Amplitude Study by Vertex pharma. Multinational study. Sure they are recruiting in your area. ------------------------------ Anurag Tikaria MD, ...
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Pregnancy in Transplant patients with aHUs and on complement inhibitors 9 hours ago
Good Afternoon, I looking to hear some experiences any of you have had in transplant patients who have a dx of aHUS and want to become pregnant....
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IgA With ANCA Positivity 10 hours ago
I have a 50-year-old male with past medical history of hypertension, obesity and prediabetes. Non smoker. Only on Lovaza and amlodipine as meds. Cr...
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RE: Tip variant FSGS 11 hours ago
I did not mean to re biopsy but wait until >1gm to treat with CNI ------------------------------ Kevin Mitchell MD Nephrologist St. Luke?s Medica...
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RE: primary Membranous nephropathy and HBV infection 12 hours ago
I would like to update regarding my patient with MN PLAR2Ab + ve and active HBV infectio . we started him on entecavir 2 months back and HBV DNA is...
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RE: Tip variant FSGS 12 hours ago
I would be hesitant to biopsy to convince mother, nor do I think doing it at a relapse would impact management. What has worked for me (sometimes) ...
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RE: FSGS Tip Variant 12 hours ago
This appeared in related content, so I thought to update community on outcome. Re-initiated Pred 1mg/kg to which he responded in 8 weeks, at which ...
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RE: candiduria after starting cephalexin while already on empagliflozin 25 mg qd for months 13 hours ago
Her 2-year Kidney Failure Risk Equation score is 9%, her 5-year score is 25%. She has time on her side for risk of progression. I would consider ce...
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RE: Renal Biopsy Post Plex 14 hours ago
We typically will use FFP for PLEX if the patient is undergoing a procedure or biopsy. Octoplas should be fine since it is used for acquired defici...
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RE: candiduria after starting cephalexin while already on empagliflozin 25 mg qd for months 14 hours ago
Such "disrespect" (haha) for aldactone! Actually, there is a lot of clinical evidence that it reliably reduces both urine protein and BP in diabeti...
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RE: Anti Gbm Case 15 hours ago
Hi prof what it they don’t have pulmonary symptoms or pulmonary haemorrhage . Can you treat in view of preventing occurrence of pulmonary haemorrha...
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Tip variant FSGS 15 hours ago
18 Y M who I treated tip variant FSGS with a longer steroid taper at the age of 16. Previous biopsy showed no tubulointerstial fibrosis also withou...
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RE: candiduria after starting cephalexin while already on empagliflozin 25 mg qd for months 18 hours ago
Does the rash occurred after antibiotic initiation? As I massively use finerenone in DKD patients and didn’t encountered this AE. I have a practic...
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RE: candiduria after starting cephalexin while already on empagliflozin 25 mg qd for months 23 hours ago
Good point! If no harms are done why not give it a try. ------------------------------ Richard Glassock MD, FASN Laguna Woods CA (949) 388-8885 -...
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RE: Anti Gbm Case 1 day ago
If a patient with anti-GBM disease has 100% glomerular crescent, oliguria and dialysis dependence, we still treat with PLEX if DAH is present and a...
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RE: candiduria after starting cephalexin while already on empagliflozin 25 mg qd for months 1 day ago
@Richard Glassock You have me there at spironolactone. There is no good clinical evidence only experimental evidence that it would be useful in ...
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RE: Anti Gbm Case 1 day ago
C3 normal. Will send echo , blood cultures , cryo and repeat ds dna, Ana. Not behaving in septic manner tho. If patient has anti gbm with renal ...
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RE: KFRE 1 day ago
Thanks prof glassock --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------
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RE: Renal Biopsy Post Plex 1 day ago
Thanks prof --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------
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RE: Case 1 day ago
Thanks dr Rodby thought like you. Patient also not keen on biopsy --------------------------------- Muhammad Soobadar MBChB UK ----------------...
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RE: membranous GN with advanced CKD-treatment plan 1 day ago
Thank u dr Glassock --------------------------------- Alaa Nabih Abdalla nephrology fellow Egypt ---------------------------------
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RE: C3G case 1 day ago
Many thanks for these suggestions. I think tgat a search for concealed monoclonal Ig deposits is warranted in this case. I am very skeptical of a d...
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RE: IgA nephropathy with serum ANCA positivite ( ANA is negative) with no proteinuria 1 day ago
None of these medications are associated with crescent formation in glomeruli, as far as I know. ------------------------------ Richard Glassock ...
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RE: membranous GN with advanced CKD-treatment plan 1 day ago
Yes. Glomerular hypercellularity is not seen in MN even when active in situ formation of sub-epithelial IC is occurring. Recently formation of in s...
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RE: candiduria after starting cephalexin while already on empagliflozin 25 mg qd for months 1 day ago
I agree with local anti-fungal therapy and teaching better genital hygiene, with temporary withholding of Flozins.. I am a little more skeptical of...
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RE: candiduria after starting cephalexin while already on empagliflozin 25 mg qd for months 1 day ago
Re the candiduria it is very much likely that she has vaginal candidiasis which has shown up in the urine culture. Vaginal cotrimazole cream may be...
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RE: membranous GN with advanced CKD-treatment plan 1 day ago
Can intra -membranous deposits . . indicate active in situ formation of IC although there is no endocapilary hypercellularity or any other active l...
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RE: IgA nephropathy with serum ANCA positivite ( ANA is negative) with no proteinuria 1 day ago
Thank you for your input. He is ANA negative. No crescents in biopsy and no proteinuria. I sent repeat ANCA and MPO which is pending currently. -...
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RE: IgA nephropathy with serum ANCA positivite ( ANA is negative) with no proteinuria 1 day ago
Medications : ASA, Atorvastatin, Levothyroxine, Vit D, Coreg and Cozaar. Cozaar started recently. ------------------------------ Radhika Thalla M...
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RE: C3G case 1 day ago
Your pathologist can probably get pronase from you molecular lab. They would routinely use either pronase or proteinase K for DNA extractions. This...
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RE: C3G case 2 days ago
Thank you both dear Dr. @Richard Glassock and @Awais Nauman for your reply and clarification. ------------------------------ Rowan Zyada MSc Egy...
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RE: Drug induced ANCA disease or IgA with crescents? 2 days ago
My reckless brain wonders how "Hydralazine" or "Similarly accused meds" can induce antibody production towards histones -/+ MPO & turn the place in...
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RE: IgA nephropathy with serum ANCA positivite ( ANA is negative) with no proteinuria 2 days ago
Recent studies have shown that ANCA positivity in IgA N is seen in about 2% of patients abd tge clinical feature are similar with or without AbCA e...
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