Anticoagulation in Dialysis Recipients with Atrial Fibrillation Wednesday, April 9 @ 12:00 PM * 31 minutes
Dr. Ziv Harel discusses findings from his study, "Anticoagulation for Patients with Atrial Fibrillation Receiving Dialysis: A Pilot Randomized Controlled Trial," with JASN Deputy Editor Manjula Kurella Tamura.
CASR Determines Renal Response to Hypercalcemia Friday, March 21 @ 8:50 AM * 31 minutes
Drs. Henrik Dimke and Nina Himmerkus discuss the results of their study, "Calcium-Sensing Receptor in the Thick Ascending Limb and the Renal Response to Hypercalcemia," with JASN Deputy Editor David H. Ellison.
ASN Kidney Translation Series: ASN Kidney Health Guidance on the Outpatient Management of Patients with Dialysis-Requiring Acute Kidney Injury Tuesday, March 11 @ 12:35 PM * 34 minutes
The ASN Kidney Health Guidance on the Outpatient Management of Patients with Dialysis-Requiring Acute Kidney Injury provides strategies to optimize recovery, implement individualized care, and coordinate best practices in AKI-D management.
ASN Kidney Translation Series: Kidney Stones Tuesday, February 25 @ 4:40 PM * 51 minutes
In this episode of the ASN Kidney Translation Podcast series, Dr. Matthew Sparks dives into groundbreaking kidney stone research from JASN, CJASN, and Kidney360, exploring CKD risk, asymptomatic stone passage, and how pharmacotherapy affects recurrence.
Molecular Signature of NPCs in the Catshark Wednesday, January 22 @ 12:00 AM * 25 minutes
Drs. Agnès Boutet and Yasmine Lund-Ricard discuss the findings from their study, "Postembryonic Maintenance of Nephron Progenitor Cells with Low Translational Activity in the Chondrichthyan Scyliorhinus canicula," with JASN Deputy Editor David H. Ellison.
Acetazolamide and the Kidney in T1D December 23, 2024 @ 5:00 PM * 34 minutes
Dr. Charles Ginsberg discusses the results of his study, "Acetazolamide Therapy and Kidney Function in Persons with Nonalbuminuric Diabetes Mellitus Type 1," with JASN Deputy Editor Manjula Kurella Tamura.
Kidney Protection by Acetylcholine December 5, 2024 @ 10:40 AM * 12 minutes
Drs. Luan D. Truong, Richard J. Johnson, and Gabriela Espinosa Garcia discuss the findings from their study, "Production of Acetylcholine by Podocytes and its Protection from Kidney Injury in Glomerulonephritis," with JASN Deputy Editor Alessia Fornoni.
ASN Kidney Translation Series: Genetic Testing in Nephrology November 15, 2024 @ 9:00 AM * 1 hour 4 minutes
On this ASN Kidney Translation episode, Dr. Matthew Sparks hosts discussions on nephrology research in genetics. Topics include genetic testing in CKD, ADTKD screening, and digenic Alport syndrome insights.
JASN Welcomes Basic Science Research November 4, 2024 @ 12:00 PM * 12 minutes
JASN encourages investigators to submit their basic science original research to the journal. Editor-in-Chief Rajnish Mehrotra and Deputy Editors Alessia Fornoni and David H. Ellison discuss the types of basic research that JASN publishes.
ASN Kidney Translation Series: Novel Therapies for IgA Nephropathy October 26, 2024 @ 7:30 PM * 1 hour 11 minutes
Novel therapies for IgA nephropathy are discussed in this ASN Kidney Translation podcast episode, including efficacy and safety of ravulizumab, selective endothelin receptor antagonist SC0062, and long-term results from a study of atacicept as treatment.
Polycystin-2 Regulates Natriuretic Peptide Production October 8, 2024 @ 3:25 PM * 17 minutes
Drs. Ivana Kuo and Karla M. Márquez-Nogueras discuss the results of their study, "Cardiac Localized Polycystin-2 in the Natriuretic Peptide Signaling Pathway and Hypertension," with JASN Deputy Editor David H. Ellison.
ASN Kidney Translation Series: ASN Kidney Health Guidance on the Management of Obesity in Persons Living with Kidney Diseases September 18, 2024 @ 12:00 PM * 38 minutes
The inaugural ASN Kidney Health Guidance on the Management of Obesity in Persons Living with Kidney Diseases examines psychosocial considerations, lifestyle modifications, pharmacologic options, and metabolic/bariatric surgery.
KLF15 Agonist in Kidney Disease September 4, 2024 @ 9:00 AM * 18 minutes
Drs. Sandeep K. Mallipattu and Bhaskar Das discuss the findings from their study, "A Small Molecule Agonist of Krüppel-Like Factor 15 in Proteinuric Kidney Disease," with JASN Deputy Editor Alessia Fornoni.
Stem Cells in Renovascular Disease August 21, 2024 @ 9:00 AM * 15 minutes
Dr. Lilach O. Lerman discusses the results from her study, "Renovascular Disease and Mitochondrial Dysfunction in Human Mesenchymal Stem Cells," with JASN Deputy Editor Alessia Fornoni.
ASN Kidney Translation Series: Gender Equity in Nephrology August 14, 2024 @ 9:00 AM * 52 minutes
Issues of gender equity in nephrology are covered in an episode of ASN Kidney Translation: An ASN Journals' Podcast, including equal access to mentorship and research opportunities, fellowship programs' parental leave policies, and representation in RCTs.
Complications of Uninephrectomy July 31, 2024 @ 5:00 PM * 35 minutes
Drs. Alicia A. McDonough and Aurelie Edwards discuss the findings from their study, "Potassium-Alkali–Enriched Diet, Hypertension, and Proteinuria following Uninephrectomy," with JASN Deputy Editor David H. Ellison.
JASN Welcomes Late-Breaking Clinical Trial Manuscript Submissions July 1, 2024 @ 12:30 PM * 13 minutes
JASN encourages investigators to submit their late-breaking clinical trial manuscripts for rapid consideration and peer review and, if accepted, online publication in JASN concurrent with Kidney Week.
sGC Activator Avenciguat for CKD June 27, 2024 @ 10:00 AM * 22 minutes
Dr. Hiddo J.L. Heerspink discusses the findings from his study, "Effect of Avenciguat on Albuminuria in Patients with CKD: Two Randomized Placebo-Controlled Trials" with JASN Editor-in-Chief Rajnish Mehrotra.
Absolute CKD Progression Risk June 18, 2024 @ 10:00 AM * 28 minutes
Drs. Maria Clarissa Tio and Tariq Shafi discuss the findings from their study, "Individualized Risk of CKD Progression among US Adults" with JASN Deputy Editor Manjula Kurella Tamura.
ASN Kidney Translation Series: PPI, Antivirals, and Cough Syrups: Nephrotoxins and Kidney Injury May 16, 2024 @ 2:00 PM * 1 hour 9 minutes
The effect of pantoprazole on eGFR slope, antiviral medications for Herpes Zoster, & link between pediatric AKI in Uzbekistan and cough syrups are covered in this episode of ASN Kidney Translation: An ASN Journals' Podcast.
Tubular Effect of Proteinuria May 1, 2024 @ 4:00 PM * 11 minutes
Andrew Hall discusses results of his study, "Spatiotemporal Landscape of Kidney Tubular Responses to Glomerular Proteinuria," with JASN Deputy Editor David H. Ellison.
Set7 Regulates Glomerular Injury April 25, 2024 @ 3:00 PM * 26 minutes
Assam El-Osta discusses the findings from his study, "Set7 Methyltransferase and Phenotypic Switch in Diabetic Glomerular Endothelial Cells," with JASN Deputy Editor David H. Ellison.
Daprodustat and Heart Failure in CKD April 10, 2024 @ 4:00 PM * 19 minutes
Jonathan W. Cunningham and Ajay K. Singh discuss the results of their study, "Daprodustat and Heart Failure in CKD," with JASN Deputy Editor David H. Ellison.
Changes in ESKD Incidence March 13, 2024 @ 3:00 PM * 11 minutes
Susan R. Mendley and Chyng-Wen Fwu discuss the findings of their study, "Age- and Race-Specific Changes in ESKD Incidence over Four Decades," with JASN Editor-in-Chief Rajnish Mehrotra.
Dr. Briggs and Dr. Mehrotra discuss the next chapter for JASN January 12, 2024 @ 2:25 PM * 26 minutes
In this podcast, outgoing Editor-in-Chief Josie Briggs talks with incoming Editor-in-Chief Raj Mehrotra about his vision for the next chapter of JASN.
SGLT2 Inhibitors and Continuation of Renin Angiotensin Blockade November 21, 2023 @ 11:00 AM * 21 minutes
Dr. Briggs and Brendon Neuen discuss his paper in the December issue of JASN. This article on the CREDENCE and EMPA-CKD clinical trials shows that SGLT2 inhibitors allow more consistent use of RAS blockade in patients with declining renal function.
Kidney Transplant Registry Data: Advice for Users October 24, 2023 @ 12:05 PM * 19 minutes
In this podcast, EIC Josie Briggs talks with Associate Editor John Gill about the valuable data resources for research on kidney transplantation. Drs. Gill and Briggs provide some advice for users of these important resources.
Next Steps in Development of Mesenchymal Stem Cells as Possible Therapeutic for Kidney Disease October 10, 2023 @ 10:30 AM * 26 minutes
In this podcast, EIC Josie Briggs talks with Giuseppe Remuzzi about the NEPHSTROM Trial & the next steps in translational work to test the possibility that mesenchymal stem cells can be used as a therapeutic agent to promote repair of kidney damage.
Historical Redlining and the Incidence of Kidney Failure in US Cities August 24, 2023 @ 6:21 PM * 16 minutes
In the podcast, EIC Josie Briggs discusses a paper entitled "Structural Racism, Historical Redlining, and Incidence of Kidney Failure in US Cities" with co-authors Kevin Nguyen and Deidre Crews.
Antibiotic Use & Kidney Stones and Sodium Bicarbonate & the Vascular Dysfunction of CKD July 24, 2023 @ 4:40 PM * 10 minutes
In the episode, EIC Josie Briggs discusses a randomized control trial addressing the impact of sodium bicarbonate on the vascular dysfunction in CKD and an observational case control study of the impact of antibiotic use on kidney stone formation.
How Many Nephrons in a Human Kidney? A New Number and a Discussion of Why it Matters June 22, 2023 @ 2:00 PM * 15 minutes
In this podcast, Dr. Josie Briggs discusses with Dr. Andrew Rule his latest study showing the need to revise our estimate of the number of nephrons in the human kidney.
The Angiopoietin-Tie 2 Pathway is Ischemic Kidney Injury May 23, 2023 @ 2:15 PM * 19 minutes
In this episode, JASN Associate Editor Katalin Susztak talks with Dr. Susan Quaggin about work from her laboratory on ischemic injury and translational targets in the Angiopoietin-Tie 2 pathway.
Urea and Uremia April 24, 2023 @ 9:50 AM * 16 minutes
JASN EIC Josie Briggs talks with Deputy Editor Tom Hostetter about the unsolved problem of the chemical causes of the uremic syndrome. A new study reports a correlation of outcomes in CKD with protein carbamylation, a breakdown product of urea.
Genomic Diagnostic Methods for CKD April 3, 2023 @ 2:30 PM * 10 minutes
This podcast covers two papers, one describes a clinical workflow for incorporating whole exome sequencing and the other provides evidence genomic disorders contribute to monogenic CKD in adults and children.
Intensive BP Control and CKD Progression and Prognosis in Anti-GBM Disease February 27, 2023 @ 11:50 AM * 10 minutes
In the March podcast, Dr. Briggs discusses a study that addresses prognostic measures in Anti-GBM Disease and a meta-analysis of studies testing whether intensive blood pressure controls slows progression of CKD.
Pregnancy Risk for Kidney Patients; Cost Effectiveness Research in Dialysis January 30, 2023 @ 2:40 PM * 12 minutes
In this Podcast, Dr. Briggs summarizes the goals of the new JASN Special Series, Health Policy Catalyst, and summarizes papers focusing on cost effectiveness research in nephrology and on the special risk of unwanted pregnancies for kidney patients.
Use of Kidney Organoids to Study Steroid-Resistant Nephrotic Syndrome January 5, 2023 @ 9:45 AM * 20 minutes
In this podcast, Dr. Briggs discusses organoid studies with author Dr. Melissa Little. The work explores the varied molecular mechanisms of specific mutations that cause SRNS and suggests promise for eventual design of mutation-specific treatments.
Highlights in Renal Transplantation December 19, 2022 @ 3:00 PM * 23 minutes
In this podcast, EIC Dr Briggs discusses two studies on kidney transplantation with Dr. John Gill. Topics discussed include novel molecular markers and the role of HLA-DQ mismatches, work suggesting new approaches to reduce chronic graft loss.
Comparing Costs of Hemodialysis and Peritoneal Dialysis November 10, 2022 @ 10:30 AM * 18 minutes
In this podcast, EIC Josie Briggs talks with Lekha Tummalapalli about a study addressing costs of hemodialysis and peritoneal dialysis. An editorial on this issue is published in the November (33.11) issue of JASN.
Gender Differences in Care of CKD Patients October 11, 2022 @ 1:30 PM * 12 minutes
In this podcast, JASN EIC, Josie Briggs talks with Juan-Jesus Carrero, Professor of Kidney Disease Epidemiology at Karolinska Institute. His study, published in the October issue of JASN, documents striking differences in care of men and women with CKD.
Climate Change: Implications for Nephrology September 14, 2022 @ 2:00 PM * 8 minutes
In this episode we cover two papers that examine the impact of climate change on nephrology practice. Specifically, the effect of extreme weather events on hemodialysis patient mortality and greenhouse gas emissions associated with dialysis treatment.
August 2022 JASN Highlights: Addressing CKD Progression and Hazards of Intradialytic Hypotension August 17, 2022 @ 11:45 AM * 9 minutes
Two highlighted clinical studies: the first addresses the effect of combining a SGLT2 inhibitor and a MRA on proteinuria; the second considers vascular reactivity as a risk factor for cerebral hypoxia when blood pressure falls during dialysis treatments.
Addressing Racial and Ethnic Disparities in Kidney Disease July 13, 2022 @ 11:30 AM * 21 minutes
In this podcast, Dr. Briggs and JASN Deputy Editor, Dr. Donald Wesson discuss the special series highlighted in the July Issue. The series focuses on kidney health disparities with an emphasis on strategies for their elimination.
Discontinuing Immunosuppressant Use after Allograft Failure: Do We Have the Answers? June 15, 2022 @ 10:00 AM * 6 minutes
Dr. Briggs summarizes findings in a study published in the June issue of JASN. The study examines the impact of continued immunosuppression in patients with failed allografts; the effects are surprising and suggest current guidelines may not be optimum.
A New Approach to Advance Care Planning for Dialysis Decisions: Deciding not to Decide May 25, 2022 @ 10:15 AM * 22 minutes
In this podcast Dr. Briggs talks with Dr. Kate Butler about advance care planning for patients with chronic kidney disease.
JASN May 2022 Highlights: Inflammation as a Driver of CKD Progression May 10, 2022 @ 3:30 PM * 9 minutes
In the May 2022 JASN highlights, Dr. Briggs summarizes two important studies on the role of inflammation as a driving factor in the progression of CKD.
Roxadustat and the Interpretation of Non-Inferiority April 11, 2022 @ 2:30 PM * 16 minutes
In this Podcast, JASN EIC, Josie Briggs, discusses a clinical trial from the April issue on roxadustat in dialysis patients with Magdalene Assimon. Dr. Assimon explains the interpretation of the finding that roxadustat is non-inferior to epoetin alpha.
The Renal Framingham - CVD Prediction March 17, 2022 @ 12:00 AM * 23 minutes
Kidney patients are at high risk for cardiovascular disease. In this Podcast, Dr. Briggs talks and Dr. David Charytan discuss recent work to improve the prediction of CVD in kidney patients. New work from CRIC aims to update the Framingham equation.
Lowering GFR to Protect GFR! February 16, 2022 @ 12:00 AM * 19 minutes
In this episode, Dr. Josie Briggs and Dr. Brendon Neuen discuss the GFR paradox: SGLT inhibitors and other kidney-protective drugs initially cause a drop in GFR.
Insights into Collapsing Glomerulopathy January 12, 2022 @ 12:00 AM * 17 minutes
Josie Briggs talks with Nicholas Steers about his work using inbred mice strains to understand the genetic factors that result in collapsing focal segmental glomerulosclerosis in HIV nephropathy, insights also relevant to a rare complication of COVID-19
The Immune Responses to COVID-19 in Transplant Patients November 23, 2021 @ 12:00 AM * 14 minutes
In this podcast JASN EIC, Josie Briggs talks with transplant expert and JASN Associate Editor, Matt Griffin about two studies that examine the immune responses to COVID-19 in transplant patients.
JASN November 2021 Issue Highlights November 18, 2021 @ 12:00 AM * 10 minutes
Each issue of JASN contains Highlights, short summaries of a few of the articles in the issue, chosen by the EIC as of special interest to our readers.
JASN October 2021 Issue Highlights October 14, 2021 @ 12:00 AM * 9 minutes
Each issue of JASN contains Highlights, short summaries of a few of the articles in the issue, chosen by the EIC as of special interest to our readers.
New Directions for Clinical Trials in Kidney Disease September 8, 2021 @ 4:15 PM * 32 minutes
A conversation with EIC, Josie Briggs and leading nephrology clinical trialist, Vlado Perkovic - on the next generation of clinical trials in nephrology.
JASN August 2021 Issue Highlights August 9, 2021 @ 12:00 AM * 7 minutes
A few articles in each issue are chosen by the EIC for their interest. The issue highlights include: laminin-521 –a novel GBM autoantigen, iron biomarkers & mortality in nondialysis kidney disease, & disparities among hemodialysis patients with COVID-19.
Lost Opportunities for Kidney Transplant July 30, 2021 @ 12:00 AM * 5 minutes
Transplant candidates with top 20% Estimated Post-Transplant Survival (EPTS) scores are prioritized to receive optimal deceased-donor kidneys. A study found fewer than half of eligible ESKD patients w/ top 20% EPTS scores were on transplant waiting list.
The Extracellular Matrix in Development, Aging, and Disease July 27, 2021 @ 12:00 AM * 4 minutes
The extracellular matrix (ECM) biomechanically regulates nephrogenesis, and abnormal ECM is a histologic feature of kidney aging and disease. Two reports in this issue use state-of-the-art methods to characterize the ECM in development, aging and disease.
Vaccine Acceptability and Hemodialysis Patients July 7, 2021 @ 12:00 AM * 18 minutes
A discussion between Dr. Magdalene Assimon, one of the JASN editorial fellows and study authors Dr. Pablo Garcia and Dr. Shuchi Anand on their recent JASN paper titled, "SARS-CoV-2 Vaccine Acceptability in Patients on Hemodialysis: A Nationwide Survey."
COVID-19 Mortality and the Tough Discussions about Advance Care Planning June 11, 2021 @ 3:06 PM * 8 minutes
The June issue of JASN features new population level data from CMS on the real burden of the pandemic for dialysis and transplant patients in the US. These grim numbers remind us of the important role nephrologists play in Advance Care Planning.
New Insights into the Mechanisms of Kidney Disease: Understanding Hypercholesterolemia in CKD; ADAM10 and Immune Injury to the Podocyte Slit Diaphragm June 3, 2021 @ 2:37 PM * 6 minutes
Two papers published this month in JASN provide new insights into these unsolved questions: Why is the risk of atherosclerotic cardiovascular disease so high in kidney patients? Why is the podocyte slit diaphragm so vulnerable to immunological injury?
JASN May 2022 Issue Highlights May 7, 2021 @ 12:00 AM * 11 minutes
Every issue of JASN includes Highlights, which are short summaries of 5-6 articles hand-picked by the EIC for their interest and impact.
JASN April 2021 Issue Highlights April 1, 2021 @ 12:00 AM * 9 minutes
Every issue of JASN includes Highlights, which are short summaries of 5-6 articles hand-picked by the EIC for their interest and impact.
JASN March 2021 Issue Highlights March 1, 2021 @ 12:00 AM * 10 minutes
Every issue of JASN includes Highlights, which are short summaries of 5-6 articles hand picked by the EIC for their interest and impact.
JASN February 2021 Issue Highlights February 1, 2021 @ 12:00 AM * 9 minutes
Every issue of JASN includes Highlights, which are short summaries of 5-6 articles hand picked by the EIC for their interest and impact.
JASN January 2021 Issue Highlights December 30, 2020 @ 12:10 PM * 8 minutes
Every issue of JASN includes Highlights, which are short summaries of 5-6 articles hand picked by the EIC for their interest and impact.
A Conversation with Mark Knepper and Josie Briggs: Does SARS-CoV2 Infect the Kidney? November 24, 2020 @ 4:14 PM * 14 minutes
This episode of the JASN Podcast is a discussion between JASN EIC, Josie Briggs and Deputy Editor, Mark Knepper about the question: Does SARS CoV2 Infect the Kidney?
A Dialogue with Mahboob Rahman and Erin Barreto About Ambulatory Blood Pressure Monitoring in Patients with Chronic Kidney Disease September 24, 2020 @ 12:00 PM * 19 minutes
In this podcast, JASN Editorial Fellow Dr. Erin Barreto interviews lead author, Dr. Mahboob Rahman, about his recent paper on blood pressure patterns detected with ambulatory blood pressure monitoring and implications on outcomes for CKD patients.
A Discussion with Andrew Malone and Madhav Menon: RNAseq and the Transplant Biopsy, What is New? August 7, 2020 @ 8:30 AM * 23 minutes
In this podcast, JASN Editorial Fellow Dr. Madhav Menon, discusses with Dr. Andrew Malone a novel application of RNAseq to the transplant biopsy.
A Conversation with Deidre Crews and Tanjala Purnell about COVID-19, Structural Racism and Kidney Disease July 21, 2020 @ 3:00 PM * 21 minutes
This episode, JASN's inaugural podcast, is a conversation with Drs. Tanjala Purnell and Deidre Crews, about the impact of the COVID-19 epidemic on kidney patients, particularly the disproportionate impact on people of color.