- Small Molecule Inhibition of APOL1 Channel Activity Protects Podocytes from Mitochondrial Dysfunction, Cell Death, and Barrier Disruption Induced by APOL1 Risk Variants
10:00 AM - 12:00 PM
Small Molecule Inhibition of APOL1 Channel Activity Protects Podocytes from Mitochondrial Dysfunction, Cell Death, and Barrier Disruption Induced by APOL1 Risk Variants
October 26, 2024 | 10:00 AM - 12:00 PM
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- Small Molecule APOL1 Channel Inhibitor Reduces Proteinuria, Rescues Podocyte Injury, and Reverses eGFR Decline in an APOL1-Mediated Kidney Disease Mouse Model
10:00 AM - 12:00 PM
Small Molecule APOL1 Channel Inhibitor Reduces Proteinuria, Rescues Podocyte Injury, and Reverses eGFR Decline in an APOL1-Mediated Kidney Disease Mouse Model
October 26, 2024 | 10:00 AM - 12:00 PM
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- A Kidney-Specific Fasting-Mimicking Diet Induces Podocyte Reprogramming and Restores Kidney Function in Glomerulopathy
10:00 AM - 12:00 PM
A Kidney-Specific Fasting-Mimicking Diet Induces Podocyte Reprogramming and Restores Kidney Function in Glomerulopathy
October 26, 2024 | 10:00 AM - 12:00 PM
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- Canagliflozin Reduces Podocyte Hypertrophic Stress and Progression of Nephropathy by Suppressing the mTOR/p70S6K/cyclin D1 Signaling Pathway in a Model of Obesity-Related Nephropathy
10:00 AM - 12:00 PM
Canagliflozin Reduces Podocyte Hypertrophic Stress and Progression of Nephropathy by Suppressing the mTOR/p70S6K/cyclin D1 Signaling Pathway in a Model of Obesity-Related Nephropathy
October 26, 2024 | 10:00 AM - 12:00 PM
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- MAP4K1 Downregulation by Glucagon-Like Peptide 1 (GLP-1) Receptor Agonists Alleviates Podocyte Injury and Inflammation via the cGAS-STING Pathway in Glomerular Diseases
10:00 AM - 12:00 PM
MAP4K1 Downregulation by Glucagon-Like Peptide 1 (GLP-1) Receptor Agonists Alleviates Podocyte Injury and Inflammation via the cGAS-STING Pathway in Glomerular Diseases
October 26, 2024 | 10:00 AM - 12:00 PM
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- Reversal of Established CKD by Weekly Subcutaneous Recombinant Human Mutated Angiopoietin-Like 4
10:00 AM - 12:00 PM
Reversal of Established CKD by Weekly Subcutaneous Recombinant Human Mutated Angiopoietin-Like 4
October 26, 2024 | 10:00 AM - 12:00 PM
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- Trametinib Ameliorated Adriamy-Induced Podocyte Injury In Vivo and In Vitro by Inhibiting METTL3-Mediated RCAN1 m6A RNA Methylation
10:00 AM - 12:00 PM
Trametinib Ameliorated Adriamy-Induced Podocyte Injury In Vivo and In Vitro by Inhibiting METTL3-Mediated RCAN1 m6A RNA Methylation
October 26, 2024 | 10:00 AM - 12:00 PM
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- Autophagic Inhibitor ROC-325 Ameliorates Glomerulosclerosis and Podocyte Injury via Inhibiting Autophagic Flux in Experimental FSGS Mice
10:00 AM - 12:00 PM
Autophagic Inhibitor ROC-325 Ameliorates Glomerulosclerosis and Podocyte Injury via Inhibiting Autophagic Flux in Experimental FSGS Mice
October 26, 2024 | 10:00 AM - 12:00 PM
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- Pharmacologic Inhibition of Urokinase-Type Plasminogen Activator Receptor (uPAR)-Formyl Peptide Receptor (FPR) Signaling Prevents Podocyte Damage in Primary Podocytopathies
10:00 AM - 12:00 PM
Pharmacologic Inhibition of Urokinase-Type Plasminogen Activator Receptor (uPAR)-Formyl Peptide Receptor (FPR) Signaling Prevents Podocyte Damage in Primary Podocytopathies
October 26, 2024 | 10:00 AM - 12:00 PM
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- Voclosporin Ameliorates Proteinuria and Directly Protects Podocytes in a Model of Noninflammatory Glomerular Disease
10:00 AM - 12:00 PM
Voclosporin Ameliorates Proteinuria and Directly Protects Podocytes in a Model of Noninflammatory Glomerular Disease
October 26, 2024 | 10:00 AM - 12:00 PM
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- Similarities and Differences in Gene Expression between Glucocorticoids and Pioglitazone in a Rodent Model of Nephrotic Syndrome
10:00 AM - 12:00 PM
Similarities and Differences in Gene Expression between Glucocorticoids and Pioglitazone in a Rodent Model of Nephrotic Syndrome
October 26, 2024 | 10:00 AM - 12:00 PM
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- miR-193a and Nanoparticle Technology: A Novel Therapeutic Approach for Alport Syndrome
10:00 AM - 12:00 PM
miR-193a and Nanoparticle Technology: A Novel Therapeutic Approach for Alport Syndrome
October 26, 2024 | 10:00 AM - 12:00 PM
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- Dapagliflozin in Addition to Ramipril Ameliorates Kidney Disease Progression in Mice with Alport Syndrome
10:00 AM - 12:00 PM
Dapagliflozin in Addition to Ramipril Ameliorates Kidney Disease Progression in Mice with Alport Syndrome
October 26, 2024 | 10:00 AM - 12:00 PM
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- Reducing Proteinuria by Antagonizing αVβ3 Integrin with a Novel Inducible Co-stimulator Ligand-Based Peptide
10:00 AM - 12:00 PM
Reducing Proteinuria by Antagonizing αVβ3 Integrin with a Novel Inducible Co-stimulator Ligand-Based Peptide
October 26, 2024 | 10:00 AM - 12:00 PM
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- Stabilization of Integrin a3b1 with Novel Activating Antibodies Protects against FSGS
10:00 AM - 12:00 PM
Stabilization of Integrin a3b1 with Novel Activating Antibodies Protects against FSGS
October 26, 2024 | 10:00 AM - 12:00 PM
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- Activation of Podocyte-Specific MC5R Signaling by Melanocortin Therapy Protects against THSD7A-Associated Membranous Nephropathy
10:00 AM - 12:00 PM
Activation of Podocyte-Specific MC5R Signaling by Melanocortin Therapy Protects against THSD7A-Associated Membranous Nephropathy
October 26, 2024 | 10:00 AM - 12:00 PM
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- A Novel IKKβ Inhibitor Ameliorates Podocyte and Kidney Injuries
10:00 AM - 12:00 PM
A Novel IKKβ Inhibitor Ameliorates Podocyte and Kidney Injuries
October 26, 2024 | 10:00 AM - 12:00 PM
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- Lymphatic Dysfunction and Perirenal Adiposity: Role of Glucocorticoids
10:00 AM - 12:00 PM
Lymphatic Dysfunction and Perirenal Adiposity: Role of Glucocorticoids
October 26, 2024 | 10:00 AM - 12:00 PM
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- Inhibiting STAT3-Mediated Glutathione Metabolism Attenuates Parietal Epithelial Cell Activation in Proliferative Glomerulopathy
10:00 AM - 12:00 PM
Inhibiting STAT3-Mediated Glutathione Metabolism Attenuates Parietal Epithelial Cell Activation in Proliferative Glomerulopathy
October 26, 2024 | 10:00 AM - 12:00 PM
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- Selective Peroxisome Proliferator-Activated Receptor γ Modulator, GQ-16, Provides Therapeutic Efficacy in a Murine Model of Rapidly Progressive Glomerulonephritis
10:00 AM - 12:00 PM
Selective Peroxisome Proliferator-Activated Receptor γ Modulator, GQ-16, Provides Therapeutic Efficacy in a Murine Model of Rapidly Progressive Glomerulonephritis
October 26, 2024 | 10:00 AM - 12:00 PM
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- Therapeutic Targeting of Antibody-Secreting Cells for the Treatment of Autoimmune Kidney Diseases
10:00 AM - 12:00 PM
Therapeutic Targeting of Antibody-Secreting Cells for the Treatment of Autoimmune Kidney Diseases
October 26, 2024 | 10:00 AM - 12:00 PM
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- Felzartamab Selectively and Potently Targets CD38+ Antibody-Secreting Cells from Patients with Immune-Mediated Kidney Diseases
10:00 AM - 12:00 PM
Felzartamab Selectively and Potently Targets CD38+ Antibody-Secreting Cells from Patients with Immune-Mediated Kidney Diseases
October 26, 2024 | 10:00 AM - 12:00 PM
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- Moss-Produced Human Factor H (CPV-104): Pioneering Rebalancing Therapies for Kidney Complement Disorders
10:00 AM - 12:00 PM
Moss-Produced Human Factor H (CPV-104): Pioneering Rebalancing Therapies for Kidney Complement Disorders
October 26, 2024 | 10:00 AM - 12:00 PM
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- Pharmacologic Activation of CD11b Suppresses TLR7-Driven Proinflammatory Myeloid Signaling and Protects against Lupus Nephritis
10:00 AM - 12:00 PM
Pharmacologic Activation of CD11b Suppresses TLR7-Driven Proinflammatory Myeloid Signaling and Protects against Lupus Nephritis
October 26, 2024 | 10:00 AM - 12:00 PM
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- Targeting M2b Macrophages by Selenium Nanomedicine for the Treatment of Lupus Nephritis
10:00 AM - 12:00 PM
Targeting M2b Macrophages by Selenium Nanomedicine for the Treatment of Lupus Nephritis
October 26, 2024 | 10:00 AM - 12:00 PM
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- Sinomenine Alleviates Lupus Nephritis in MRL/lpr Mice by Suppressing the Noncanonical NF-kB Pathway
10:00 AM - 12:00 PM
Sinomenine Alleviates Lupus Nephritis in MRL/lpr Mice by Suppressing the Noncanonical NF-kB Pathway
October 26, 2024 | 10:00 AM - 12:00 PM
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- SGLT2 Inhibition in Nondiabetic CKD: Results in Experimental Lupus Nephritis (LN)
10:00 AM - 12:00 PM
SGLT2 Inhibition in Nondiabetic CKD: Results in Experimental Lupus Nephritis (LN)
October 26, 2024 | 10:00 AM - 12:00 PM
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- Assessing the Therapeutic Potential of a Myeloperoxidase Inhibitor in a Preclinical Rat Model of MPO-ANCA Autoimmune Vasculitis
10:00 AM - 12:00 PM
Assessing the Therapeutic Potential of a Myeloperoxidase Inhibitor in a Preclinical Rat Model of MPO-ANCA Autoimmune Vasculitis
October 26, 2024 | 10:00 AM - 12:00 PM
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- Genome Editing to Delete the Proteinase 3 Autoantigen as a Treatment Strategy for ANCA-Associated Vasculitis
10:00 AM - 12:00 PM
Genome Editing to Delete the Proteinase 3 Autoantigen as a Treatment Strategy for ANCA-Associated Vasculitis
October 26, 2024 | 10:00 AM - 12:00 PM
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- RNK288: A MASP2-Targeting Small Interfering RNA (siRNA) for the Treatment of IgA Nephropathy by Blocking the Activation of Lectin Pathway
10:00 AM - 12:00 PM
RNK288: A MASP2-Targeting Small Interfering RNA (siRNA) for the Treatment of IgA Nephropathy by Blocking the Activation of Lectin Pathway
October 26, 2024 | 10:00 AM - 12:00 PM
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- First-in-Class Antigen-Specific Extracellular Protein Degrader, BHV-1400 for IgA Nephropathy, Selectively Targets Galactose-Deficient IgA for Rapid and Efficient Endolysosomal Degradation in the Liver
10:00 AM - 12:00 PM
First-in-Class Antigen-Specific Extracellular Protein Degrader, BHV-1400 for IgA Nephropathy, Selectively Targets Galactose-Deficient IgA for Rapid and Efficient Endolysosomal Degradation in the Liver
October 26, 2024 | 10:00 AM - 12:00 PM
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- mTOR Inhibition: A Novel Regulator of Soluble CD89 Activity via the Mesangial Transferrin Receptor and Its Therapeutic Potential in IgA Nephropathy
10:00 AM - 12:00 PM
mTOR Inhibition: A Novel Regulator of Soluble CD89 Activity via the Mesangial Transferrin Receptor and Its Therapeutic Potential in IgA Nephropathy
October 26, 2024 | 10:00 AM - 12:00 PM
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- Quantitative Image Analysis Uncovers the Efficacy of the Selective Endothelin A Receptor Antagonist Atrasentan in a Rat Model of IgA Nephropathy
10:00 AM - 12:00 PM
Quantitative Image Analysis Uncovers the Efficacy of the Selective Endothelin A Receptor Antagonist Atrasentan in a Rat Model of IgA Nephropathy
October 26, 2024 | 10:00 AM - 12:00 PM
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- Development of GE8820 for Selective and Rapid Removal of Pathogenic Autoantibodies in Primary Membranous Nephritis (PMN) and Other IgG4-Mediated Diseases
10:00 AM - 12:00 PM
Development of GE8820 for Selective and Rapid Removal of Pathogenic Autoantibodies in Primary Membranous Nephritis (PMN) and Other IgG4-Mediated Diseases
October 26, 2024 | 10:00 AM - 12:00 PM
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