- Urine Proteomics Captures Unique Spatial Transcriptomic Signatures of ADPKD in a Mouse Model
10:00 AM - 12:00 PM
Urine Proteomics Captures Unique Spatial Transcriptomic Signatures of ADPKD in a Mouse Model
October 25, 2024 | 10:00 AM - 12:00 PM
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- In Vivo Analysis of Polycystin-1: Heterotrimeric G-protein Binding by NanoBiT
10:00 AM - 12:00 PM
In Vivo Analysis of Polycystin-1: Heterotrimeric G-protein Binding by NanoBiT
October 25, 2024 | 10:00 AM - 12:00 PM
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- Modeling the Impact of Polycystic Kidney Disease Genetic Modifiers Using Kidney Organoids Generated from Autologous Induced Pluripotent Stem Cells
10:00 AM - 12:00 PM
Modeling the Impact of Polycystic Kidney Disease Genetic Modifiers Using Kidney Organoids Generated from Autologous Induced Pluripotent Stem Cells
October 25, 2024 | 10:00 AM - 12:00 PM
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- Generation of Kidney Organoids Model of Nephronophthisis from Human Induced Pluripotent Stem Cells (iPSCs)
10:00 AM - 12:00 PM
Generation of Kidney Organoids Model of Nephronophthisis from Human Induced Pluripotent Stem Cells (iPSCs)
October 25, 2024 | 10:00 AM - 12:00 PM
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- Analysis of Pkd1 Gene Function in a Three-Dimensional Tubulogenesis Assay
10:00 AM - 12:00 PM
Analysis of Pkd1 Gene Function in a Three-Dimensional Tubulogenesis Assay
October 25, 2024 | 10:00 AM - 12:00 PM
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- Chemical Modulation of the Ire1α-Xbp1 Pathway Reduces Cyst Size in ADPKD Mouse and Human Three-Dimensional Spheroids
10:00 AM - 12:00 PM
Chemical Modulation of the Ire1α-Xbp1 Pathway Reduces Cyst Size in ADPKD Mouse and Human Three-Dimensional Spheroids
October 25, 2024 | 10:00 AM - 12:00 PM
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- Glis3 Is a Modifier of Cyst Progression in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
10:00 AM - 12:00 PM
Glis3 Is a Modifier of Cyst Progression in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
October 25, 2024 | 10:00 AM - 12:00 PM
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- Structural Analysis of the Extracellular Portion of Polycystin-1
10:00 AM - 12:00 PM
Structural Analysis of the Extracellular Portion of Polycystin-1
October 25, 2024 | 10:00 AM - 12:00 PM
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- Guanine Quadruplex DNA in Human PKD1 Reveals a Mechanism for Second-Hit Mutagenesis in ADPKD
10:00 AM - 12:00 PM
Guanine Quadruplex DNA in Human PKD1 Reveals a Mechanism for Second-Hit Mutagenesis in ADPKD
October 25, 2024 | 10:00 AM - 12:00 PM
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- mRNA Translation Reprogramming in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
10:00 AM - 12:00 PM
mRNA Translation Reprogramming in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
October 25, 2024 | 10:00 AM - 12:00 PM
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- Cleavage of N-terminus of Polycystin-1 Increases Calcium Permeability of Polycystin-1/Polycystin-2 Receptor Channel Complexes
10:00 AM - 12:00 PM
Cleavage of N-terminus of Polycystin-1 Increases Calcium Permeability of Polycystin-1/Polycystin-2 Receptor Channel Complexes
October 25, 2024 | 10:00 AM - 12:00 PM
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- Functional Studies of Polycystin-1 Using a Novel Pkd1-HaloTag Mouse
10:00 AM - 12:00 PM
Functional Studies of Polycystin-1 Using a Novel Pkd1-HaloTag Mouse
October 25, 2024 | 10:00 AM - 12:00 PM
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- Adult-Onset Conditional Deletion of Pkd1 and Tulp3 in Mice Exert Different Effects on Kidney Cyst Formation and Mitochondria Phenotypes
10:00 AM - 12:00 PM
Adult-Onset Conditional Deletion of Pkd1 and Tulp3 in Mice Exert Different Effects on Kidney Cyst Formation and Mitochondria Phenotypes
October 25, 2024 | 10:00 AM - 12:00 PM
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- Defining Precystic vs. Cystic Alterations in Pkd1 Renal Mutants
10:00 AM - 12:00 PM
Defining Precystic vs. Cystic Alterations in Pkd1 Renal Mutants
October 25, 2024 | 10:00 AM - 12:00 PM
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- Methylation-Controlled J Protein as a Target to Alleviate Kidney Fibrosis and Cyst Growth
10:00 AM - 12:00 PM
Methylation-Controlled J Protein as a Target to Alleviate Kidney Fibrosis and Cyst Growth
October 25, 2024 | 10:00 AM - 12:00 PM
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- Three-Dimensional Imaging and Genetic Characterisation of a Rat Model of Polycystic Kidney Disease
10:00 AM - 12:00 PM
Three-Dimensional Imaging and Genetic Characterisation of a Rat Model of Polycystic Kidney Disease
October 25, 2024 | 10:00 AM - 12:00 PM
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- Studying Macrophage Phenotype and Function in Slowly Progressing Models of PKD
10:00 AM - 12:00 PM
Studying Macrophage Phenotype and Function in Slowly Progressing Models of PKD
October 25, 2024 | 10:00 AM - 12:00 PM
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- Cell State Transition Associated with Cyst Development in Autosomal Dominant Polycystic Kidney Disease
10:00 AM - 12:00 PM
Cell State Transition Associated with Cyst Development in Autosomal Dominant Polycystic Kidney Disease
October 25, 2024 | 10:00 AM - 12:00 PM
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- Investigating the Biogenesis and Degradation of Polycystin 2 Missense Mutants
10:00 AM - 12:00 PM
Investigating the Biogenesis and Degradation of Polycystin 2 Missense Mutants
October 25, 2024 | 10:00 AM - 12:00 PM
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- Studying the Involvement of the Complement Receptor C5ar1 in Polycystic Kidney Disease
10:00 AM - 12:00 PM
Studying the Involvement of the Complement Receptor C5ar1 in Polycystic Kidney Disease
October 25, 2024 | 10:00 AM - 12:00 PM
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- Polycystins Regulate Ezrin Function and Cleavage to Control Renal Cell and Tubular Morphology
10:00 AM - 12:00 PM
Polycystins Regulate Ezrin Function and Cleavage to Control Renal Cell and Tubular Morphology
October 25, 2024 | 10:00 AM - 12:00 PM
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- Tubule-Specific Deletion of Adamts1 Slows Cyst Expansion in Polycystic Kidney Disease
10:00 AM - 12:00 PM
Tubule-Specific Deletion of Adamts1 Slows Cyst Expansion in Polycystic Kidney Disease
October 25, 2024 | 10:00 AM - 12:00 PM
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- Role of Valosin-Containing Protein (VCP) in Ciliary Morphology and ADPKD: Exploring VCP as a Novel Genetic Interactor in Disease Progression
10:00 AM - 12:00 PM
Role of Valosin-Containing Protein (VCP) in Ciliary Morphology and ADPKD: Exploring VCP as a Novel Genetic Interactor in Disease Progression
October 25, 2024 | 10:00 AM - 12:00 PM
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- Mitochondria-Targeted Antioxidant Therapy Ameliorates Arterial Dysfunction in a Mouse Model of Autosomal Dominant Polycystic Kidney Disease
10:00 AM - 12:00 PM
Mitochondria-Targeted Antioxidant Therapy Ameliorates Arterial Dysfunction in a Mouse Model of Autosomal Dominant Polycystic Kidney Disease
October 25, 2024 | 10:00 AM - 12:00 PM
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- IP1 Deletion Rescues Kidney Cyst Formation in Pkd1 KO Mouse Models
10:00 AM - 12:00 PM
IP1 Deletion Rescues Kidney Cyst Formation in Pkd1 KO Mouse Models
October 25, 2024 | 10:00 AM - 12:00 PM
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- Segment-Specific Cyst Index (SSCI): A Quantitative Analysis of Segment-Specific Responses during Cystogenesis
10:00 AM - 12:00 PM
Segment-Specific Cyst Index (SSCI): A Quantitative Analysis of Segment-Specific Responses during Cystogenesis
October 25, 2024 | 10:00 AM - 12:00 PM
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- Labeling of Denatured Collagen in ADPKD and Comparison to Fibrotic Area
10:00 AM - 12:00 PM
Labeling of Denatured Collagen in ADPKD and Comparison to Fibrotic Area
October 25, 2024 | 10:00 AM - 12:00 PM
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- Role of Ankyrin Repeat and Single KH Domain 1 in Autosomal Dominant Polycystic Kidney Disease Pathogenesis and CyclinD1/CDK4-Induced Proliferation
10:00 AM - 12:00 PM
Role of Ankyrin Repeat and Single KH Domain 1 in Autosomal Dominant Polycystic Kidney Disease Pathogenesis and CyclinD1/CDK4-Induced Proliferation
October 25, 2024 | 10:00 AM - 12:00 PM
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- Activation of Toll-Like Receptor 2 Stimulated NF-κB-Mediated Inflammatory Responses and ERK-Mediated Cell Proliferation in ADPKD
10:00 AM - 12:00 PM
Activation of Toll-Like Receptor 2 Stimulated NF-κB-Mediated Inflammatory Responses and ERK-Mediated Cell Proliferation in ADPKD
October 25, 2024 | 10:00 AM - 12:00 PM
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- Activation of Apelin Receptor Inhibits Cystogenesis in a Mouse Model of Polycystic Kidney Disease
10:00 AM - 12:00 PM
Activation of Apelin Receptor Inhibits Cystogenesis in a Mouse Model of Polycystic Kidney Disease
October 25, 2024 | 10:00 AM - 12:00 PM
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- Studying the Mechanism of Kidney Resident Macrophage Niche Filling after Temporary Depletion
10:00 AM - 12:00 PM
Studying the Mechanism of Kidney Resident Macrophage Niche Filling after Temporary Depletion
October 25, 2024 | 10:00 AM - 12:00 PM
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- LSD1 Nuclear Condensation Promotes Cyst Growth in Polycystic Kidney Disease
10:00 AM - 12:00 PM
LSD1 Nuclear Condensation Promotes Cyst Growth in Polycystic Kidney Disease
October 25, 2024 | 10:00 AM - 12:00 PM
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- Lipid Metabolism Reprogramming in ADPKD
10:00 AM - 12:00 PM
Lipid Metabolism Reprogramming in ADPKD
October 25, 2024 | 10:00 AM - 12:00 PM
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- Role of Pannexin-1/P2X7 Interaction in Kidney Cyst Development
10:00 AM - 12:00 PM
Role of Pannexin-1/P2X7 Interaction in Kidney Cyst Development
October 25, 2024 | 10:00 AM - 12:00 PM
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- Specific Population of Urinary Extracellular Vesicles Distinguishes Pediatric Patients with ADPKD from Controls
10:00 AM - 12:00 PM
Specific Population of Urinary Extracellular Vesicles Distinguishes Pediatric Patients with ADPKD from Controls
October 25, 2024 | 10:00 AM - 12:00 PM
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- The Cystogenic Effects of Ouabain in Autosomal Dominant Polycystic Kidney Disease (ADPKD) Require Cell Caveolae
10:00 AM - 12:00 PM
The Cystogenic Effects of Ouabain in Autosomal Dominant Polycystic Kidney Disease (ADPKD) Require Cell Caveolae
October 25, 2024 | 10:00 AM - 12:00 PM
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- Hyper-O-GlcNAcylation of AMP-Activated Protein Kinase (AMPK) and Acetylated α-Tubulin in ADPKD Pathogenesis
10:00 AM - 12:00 PM
Hyper-O-GlcNAcylation of AMP-Activated Protein Kinase (AMPK) and Acetylated α-Tubulin in ADPKD Pathogenesis
October 25, 2024 | 10:00 AM - 12:00 PM
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- Exploring the Role of Interferon-Gamma in Injury-Accelerated Cystic Kidney Disease
10:00 AM - 12:00 PM
Exploring the Role of Interferon-Gamma in Injury-Accelerated Cystic Kidney Disease
October 25, 2024 | 10:00 AM - 12:00 PM
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- Deletion of the Homeobox Gene Cux1 Decreases Ciliogenesis in a Mouse Model of Polycystic Kidney Disease
10:00 AM - 12:00 PM
Deletion of the Homeobox Gene Cux1 Decreases Ciliogenesis in a Mouse Model of Polycystic Kidney Disease
October 25, 2024 | 10:00 AM - 12:00 PM
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- NOTCH2 Mutations Associated with Alagille Syndrome Result in Longer Primary Cilia and Inactivation of Ift88 in Mice with Notch Signaling-Deficient Kidneys Partly Rescues Kidney Abnormalities
10:00 AM - 12:00 PM
NOTCH2 Mutations Associated with Alagille Syndrome Result in Longer Primary Cilia and Inactivation of Ift88 in Mice with Notch Signaling-Deficient Kidneys Partly Rescues Kidney Abnormalities
October 25, 2024 | 10:00 AM - 12:00 PM
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- Axoneme Hypoglutamylation in Primary Cilia Promotes Cystogenesis in ADPKD
10:00 AM - 12:00 PM
Axoneme Hypoglutamylation in Primary Cilia Promotes Cystogenesis in ADPKD
October 25, 2024 | 10:00 AM - 12:00 PM
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- Loss of ARL13B's Guanine Nucleotide Exchange Factor Activity for ARL3 in Cilia Suppresses Cystogenesis in Adult Mouse Models of Polycystic Kidney Disease
10:00 AM - 12:00 PM
Loss of ARL13B's Guanine Nucleotide Exchange Factor Activity for ARL3 in Cilia Suppresses Cystogenesis in Adult Mouse Models of Polycystic Kidney Disease
October 25, 2024 | 10:00 AM - 12:00 PM
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- Tryptophan Metabolism as a Link between Cilia and Mitochondria in Renal Tubule Cells
10:00 AM - 12:00 PM
Tryptophan Metabolism as a Link between Cilia and Mitochondria in Renal Tubule Cells
October 25, 2024 | 10:00 AM - 12:00 PM
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- Defining the Interaction Network of the CPLANE Complex Reveals Cilia and Actin Regulatory Components
10:00 AM - 12:00 PM
Defining the Interaction Network of the CPLANE Complex Reveals Cilia and Actin Regulatory Components
October 25, 2024 | 10:00 AM - 12:00 PM
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- A High-Content Screening Approach to Unveil the Molecular Mechanism of the Ciliary Response to Glutamine
10:00 AM - 12:00 PM
A High-Content Screening Approach to Unveil the Molecular Mechanism of the Ciliary Response to Glutamine
October 25, 2024 | 10:00 AM - 12:00 PM
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- Klc3 Regulates Ciliary Trafficking and Cyst Formation in Kidney Epithelial Cells
10:00 AM - 12:00 PM
Klc3 Regulates Ciliary Trafficking and Cyst Formation in Kidney Epithelial Cells
October 25, 2024 | 10:00 AM - 12:00 PM
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- ANKHD1 Has a Cytoprotective Role in Stressed Kidney Cells
10:00 AM - 12:00 PM
ANKHD1 Has a Cytoprotective Role in Stressed Kidney Cells
October 25, 2024 | 10:00 AM - 12:00 PM
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- Influence of PKD1-Mediated Apoptosis on Proliferation and Autophagy in Human Embryonic Kidney Cells
10:00 AM - 12:00 PM
Influence of PKD1-Mediated Apoptosis on Proliferation and Autophagy in Human Embryonic Kidney Cells
October 25, 2024 | 10:00 AM - 12:00 PM
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- Regulated Cell Death in the Pathogenesis of Cystic Kidney Diseases
10:00 AM - 12:00 PM
Regulated Cell Death in the Pathogenesis of Cystic Kidney Diseases
October 25, 2024 | 10:00 AM - 12:00 PM
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- Autophagy Knockout Results in ERK Activation, Increased Proliferation, and Apoptosis of Cyst-Lining Epithelial Cells and Worse Polycystic Kidney Disease
10:00 AM - 12:00 PM
Autophagy Knockout Results in ERK Activation, Increased Proliferation, and Apoptosis of Cyst-Lining Epithelial Cells and Worse Polycystic Kidney Disease
October 25, 2024 | 10:00 AM - 12:00 PM
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- Pkd1 Mutation Modulates Cognitive Function via N-methyl-D-aspartate Receptor-Mediated Synaptic Transmission and Autophagy
10:00 AM - 12:00 PM
Pkd1 Mutation Modulates Cognitive Function via N-methyl-D-aspartate Receptor-Mediated Synaptic Transmission and Autophagy
October 25, 2024 | 10:00 AM - 12:00 PM
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- Neuroinflammation in Polycystic Kidney Disease
10:00 AM - 12:00 PM
Neuroinflammation in Polycystic Kidney Disease
October 25, 2024 | 10:00 AM - 12:00 PM
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