Kidney Week

Advances in Research Conference - Genome Engineering and RNA-Based Therapeutics: From Bench to Potentially Curative Medicines

Advances in Research Conference - Genome Engineering and RNA-Based Therapeutics: From Bench to Potentially Curative Medicines

October 23, 2024 | 07:00 AM - 05:10 PM

Location: Room 6A, Convention Center

Session Description

This program showcases cutting-edge advances in gene therapy, genome and epigenome editing, and RNA-based therapeutics. Lectures highlight recent technological advances, the current toolbox available to clinicians, and major clinical breakthroughs, with an eye toward potential application to the treatment of kidney diseases.

Session Objectives

Upon completion of this program, the participant will be able to: 1) describe state-of-the-art genome editing and RNA-based therapeutics technology; 2) discuss the potential clinical application of genome editing for kidney-related diseases; and 3) discuss the potential clinical application of RNA-based drugs for common kidney diseases.

Learning Pathway(s)

• Genetic Diseases and Development

Moderators

• Opeyemi A. Olabisi, MD, PhD
• Vishal Patel, MD

Presentations

• Check In and Continental Breakfast
  07:00 AM - 08:00 AM
  

Check In and Continental Breakfast

October 23, 2024 | 07:00 AM - 08:00 AM

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• Welcome and Opening Remarks
  08:00 AM - 08:10 AM
  
  • Vishal Patel, MD

Welcome and Opening Remarks

October 23, 2024 | 08:00 AM - 08:10 AM

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• Base Editing and Prime Editing: Technology and Toolbox for Correcting DNA Variants
  08:10 AM - 08:40 AM
  
  • Andrew Anzalone, MD, PhD

Base Editing and Prime Editing: Technology and Toolbox for Correcting DNA Variants

October 23, 2024 | 08:10 AM - 08:40 AM

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• Targeting the Kidneys for Gene Therapy
  08:40 AM - 09:10 AM
  
  • Matthew H. Wilson, MD, PhD

Targeting the Kidneys for Gene Therapy

October 23, 2024 | 08:40 AM - 09:10 AM

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• Back to the Microbes: Searching for New and Diverse Gene-Editing Tools
  09:10 AM - 09:40 AM
  
  • Brian C. Thomas, PhD

Back to the Microbes: Searching for New and Diverse Gene-Editing Tools

October 23, 2024 | 09:10 AM - 09:40 AM

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• Break
  09:40 AM - 10:15 AM
  

Break

October 23, 2024 | 09:40 AM - 10:15 AM

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• Delivery Approaches to Carry Genetic Cargo to Kidneys
  10:15 AM - 10:45 AM
  
  • Eun ji Chung, PhD

Delivery Approaches to Carry Genetic Cargo to Kidneys

October 23, 2024 | 10:15 AM - 10:45 AM

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• RNA Editing as a Novel Therapeutic Modality
  10:45 AM - 11:15 AM
  
  • Chikdu S. Shivalila, PhD

RNA Editing as a Novel Therapeutic Modality

October 23, 2024 | 10:45 AM - 11:15 AM

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• AAV Vector-Mediated Gene Therapy for Alport Syndrome
  11:15 AM - 11:45 AM
  
  • Hiroyuki Nakai, MD, PhD

AAV Vector-Mediated Gene Therapy for Alport Syndrome

October 23, 2024 | 11:15 AM - 11:45 AM

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• Lunch (on your own)
  11:45 AM - 01:00 PM
  

Lunch (on your own)

October 23, 2024 | 11:45 AM - 01:00 PM

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• CRISPR for the Treatment of Sickle Cell Disease
  01:00 PM - 01:30 PM
  
  • Alexis A. Thompson, MD, MPH

CRISPR for the Treatment of Sickle Cell Disease

October 23, 2024 | 01:00 PM - 01:30 PM

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• Gene Therapy for Podocytopathies
  01:30 PM - 02:00 PM
  
  • Moin A. Saleem, MD, MBBS, MBChB, PhD

Gene Therapy for Podocytopathies

October 23, 2024 | 01:30 PM - 02:00 PM

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• RNA Interference in the Treatment of Kidney Stone Disease
  02:00 PM - 02:30 PM
  
  • John C. Lieske, MD, FASN

RNA Interference in the Treatment of Kidney Stone Disease

October 23, 2024 | 02:00 PM - 02:30 PM

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• Break
  02:30 PM - 03:00 PM
  

Break

October 23, 2024 | 02:30 PM - 03:00 PM

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• RNAi Drugs to Treat Hypertension
  03:00 PM - 03:30 PM
  
  • Rhian Touyz, MD, MBChB, PhD

RNAi Drugs to Treat Hypertension

October 23, 2024 | 03:00 PM - 03:30 PM

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• miRNA Therapeutics for Polycystic Kidney Disease
  03:30 PM - 04:00 PM
  
  • Edmund Chun Yu Lee, PhD

miRNA Therapeutics for Polycystic Kidney Disease

October 23, 2024 | 03:30 PM - 04:00 PM

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• Antisense Oligonucleotide Therapy for APOL1-Mediated Kidney Disease
  04:00 PM - 04:30 PM
  
  • Peter J. Greasley, PhD

Antisense Oligonucleotide Therapy for APOL1-Mediated Kidney Disease

October 23, 2024 | 04:00 PM - 04:30 PM

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• Antisense Oligonucleotide Therapy for Preeclampsia
  04:30 PM - 05:00 PM
  
  • S. Ananth Karumanchi, MD

Antisense Oligonucleotide Therapy for Preeclampsia

October 23, 2024 | 04:30 PM - 05:00 PM

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• Closing Remarks
  05:00 PM - 05:10 PM
  
  • Opeyemi A. Olabisi, MD, PhD

Closing Remarks

October 23, 2024 | 05:00 PM - 05:10 PM

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