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To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

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Kidney Week

ASN / Education & Meetings / Kidney Week /

Basic/Clinical Science Session

Extracellular Vesicles in Kidney Diseases: Tiny Packages with Big Impact

October 24, 2024 | 10:30 AM - 12:30 PM

Location: Room 6D, Convention Center

Session Description

Extracellular vesicles (EVs) are submicron vesicles released from all cells that carry cargo and markers of the parent cells. Only recently discovered, EVs have a fundamental and evolutionarily conserved role in cellular communications. EVs are seen as novel signaling particles but are also investigated as minimally invasive diagnostic and prognostic biomarkers and drug-delivery vehicles. This session focuses on the biology of EVs and current landscape of EVs as a diagnostic tool and bioregulator in kidney diseases, from glomerular to tubular diseases and hypertension.

ASN thanks the Japanese Society of Nephrology (JSN) and JSN Ambassador, Dr. Shintaro Mandai.

Learning Objective(s)

  • Explain the biology of EVs in kidney diseases: what are they, how are they formed, and what is their role
  • Describe the diagnostic role of EVs in diabetic nephropathy
  • Discuss how EVs are novel communicators in transplantation
  • Outline novel mechanisms in the maladaptive repair of AKI to CKD
  • Define the role of EVs in hypertension and salt handling of the kidneys

Learning Pathway(s)

  • Kidney Biology and Physiology
  • Kidney Transplantation

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