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Abstract: PUB265

Cohort Study of Percutaneous Native Kidney Biopsies from Rural Center Predominantly Caucasian Groups

Session Information

Category: Glomerular Diseases

  • 1203 Glomerular Diseases: Clinical, Outcomes, and Trials

Authors

  • Thimmisetty, Ravi K., Nephrology, Cape Girardeau, Missouri, United States
  • Chintam, Kiran, Southeast hospital, Cape Girardeau, Missouri, United States
  • Braxton, Frank W., Nephrology Associates, Jackson, Missouri, United States
Background

Renal Biopsies are very consequential in clinical practice and avail in understanding of pathophysiology’s, treatment and prognosis of glomerular diseases.

Methods

Epidemiological retrospective analysis of native percutaneous kidney biopsies from a rural center. Reviewed medical records of percutaneous biopsies from 2013 to May 2019

Results

There were total of 118 percutaneous native kidney biopsies analyzed with the following results: Average age at the time of biopsy was 58.0 years (16-94). Gender wise, 59.6% were males and 39.8% were females. Unexplained acute renal failure is the most common indication for biopsy. 80.5% were Caucasians, 15.25% were African Americans. Most common histological diagnosis was Nodular glomerular sclerosis (32.20%). Next common biopsy diagnosis is ATN/AIN, combination found to be 18.64%. Third common histological diagnosis found to be FSGS (12.71%). Fourth histological diagnosis is IgA nephropathy 8.4%.

Conclusion

At our rural center, most common pathology in Caucasians found to have nodular glomerular sclerosis. 13.15% of patients have histological diabetic changes with no clinical or serological diagnosis of diabetes, suggestive of other factors inolving in pathophysiology. 31.6% of diabetics have alternate histological diagnosis. Next common pathology shown Acute/Chronic Interstitial Nephritis along with Acute tubular Necrosis, may explain the medications/infections a leading cause of Chronic Kidney Disease.

prevalence of biopsies diagnosis