Abstract: PUB109
Comparison of Cognitive Impairment by Montreal Cognitive Assessment (MoCA) with Sarcopenia in Hemodialysis Patients
Session Information
Category: Dialysis
- 701 Dialysis: Hemodialysis and Frequent Dialysis
Authors
- Lee, Heeryong, Maryknoll medical center, Busan, Korea (the Republic of)
- Ahn, Jeongmyung, Maryknoll medical center, Busan, Korea (the Republic of)
- Lee, Dong Ryeol, Maryknoll medical center, Busan, Korea (the Republic of)
- Jeon, Mi young, Maryknoll medical center, Busan, Korea (the Republic of)
- Park, Hongmin, Hallym university medical center, Seoul, Korea (the Republic of)
Background
Sarcopenia has been implicated in the increased risk for cognitive impairment. Hemodialysis patients are at increased risk for sarcopenia. In this cross-sectional study, we investigated the relationship of sarcopenia with cognitive impairment in hemodialysis patients.
Methods
Total 118 hemodialysis patients, 64 men and 54 women, aged 40 years or older were included in the study. The Montreal cognitive assessment (MoCA) was used to assess cognitive performance. The MoCA consists of seven separate items (visuospatial/executive, naming, attention, language, abstraction, delayed recall, orientation). Demographics, body composition, and history of cardiovascular diseases were assessed as covariates. The cut-off of the MoCA score of the diagnosis of cognitive impairment was 22 points. The European Working Group on Sarcopenia in Older People (EWGOP) diagnostic criteria were applied to diagnose sarcopenia. The muscle mass was measured using Bioimpedance analysis and muscle strength was measured using handgrip strength.
Results
Of the patients included, 55 (women 36.4 %) were diagnosed with sarcopenia (46.6 %). The incidence of sarcopenia was higher in older patients (67.0 vs 70.0, p=0.046), but there was no difference in other variables. There was significant difference in the cognitive impairment ratio according to the presence or absence of sarcopenia (31 (56.3%) vs 28 (44.4%), p=0.046). Odd ratio (OR) and 95% confidence interval (95% CI) of cognitive impairment was calculated sarcopenia status. Compared to non-sarcopenic, sarcopenic hemodialysis patients had the ORs of 1.09 (95% CI of 1.05-1.15, p=0.030) for cognitive impairment.
Conclusion
Sarcopenia was significantly associated with cognitive impairment in hemodialysis patients. Cognitive impairment reduces the quality of life of hemodialysis patients. Therefore, it is important to prevent sarcopenia, which can cause cognitive impairment in hemodialysis patients.