Abstract: SA-PO881
Exercise During Dialysis Ameliorates the Decline in Plasma Volume by Ultrafiltration
Session Information
- Dialysis: Cardiovascular, BP, Volume
October 27, 2018 | Location: Exhibit Hall, San Diego Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 701 Dialysis: Hemodialysis and Frequent Dialysis
Authors
- Chagolla, Jose Manuel Rodriguez, Instituto nacional de cardiología, México City, Coyoacan, Mexico
- Sanchez cardenas, Monica, UNAM, CIUDAD DE MEXICO, Mexico
- Perez-grovas, Hector Alejandro, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico, Mexico, Mexico
Group or Team Name
- Instituto nacional de cardiología "Ignacio Chávez"
Background
Patients in hemodialysis (HD) remove the excess of water and Na+ by ultrafiltration (UF) that leads to an increase of hypotensive (Ht) episodes by a decline in circulating blood volumen (CBV). Exercise (EXE) leads an increase of CBV by mechanisms like redistribution of CBV and sympathetic activation. We evaluate the effects of acute moderate aerobic EXE in CBV during UF in comparison with sessions without EXE.
Methods
19 CKD patients in regular HD (11 women, Age 40±6) were randomized for one HD session with EXE by bicycle pedaling without resistance in sitting position (P) during all the session or sedentary HD session (one in sitting P, in recumbent P or recumbent P with elastic socks). All patients received the four different sessions with BVM in line during all the session with exactly the same UF rate. Besides blood pressure and heart rate were registered.
Results
We observed a lesser decline in CBV in the EXE HD session in comparison with sedentary HD. The difference were stadistically significant (p<0.001). In EXE HD we observed lesser Ht episodes (0 vs 13), and the fall in systolic and dyastolic pressure at the end of the session were lesser in EXE HD (-3 vs. 3.6 and -0.4 vs. 1.9 mmHg). Incidentally, it was observed that the effect of EXE during dialysis on the decline in CBV was clearer among males.
Conclusion
EXE during dialysis ameliorate the decline in plama volume by UF, especially in men.
Clinical characteristics according to the intervention performed
| Sitting | Recumbent | Elastic socks | EXE | °P | |
| Differential with dry weight | 2.0 (0.93 | 2.2 (1.1) | 2.0 (0.94) | 2.1 (0.74) | 0.90 |
| KTV | 1.47 (0.33) | 1.45 (0.36) | 1.46 (0.32) | 1.49 (0.33) | 0.98 |
| Substitution (L) | 19.5 (1.8) | 19.7 (1.7) | 19.4 (2.1) | 19.3 (1.4) | 0.93 |
| Hypotension | 36.8% | 5.3% | 26.3% | 0 | .007* |
Funding
- Government Support - Non-U.S.