Abstract: SA-PO880
The Acute Effects of Intra-Dialytic Exercise on Arterial and Central Venous Oxygen Saturation and Oxygen Extraction Ratio
Session Information
- Dialysis: Cardiovascular, BP, Volume
October 27, 2018 | Location: Exhibit Hall, San Diego Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Dialysis
- 701 Dialysis: Hemodialysis and Frequent Dialysis
Authors
- Aguirre, Diana, Hospital General "Dr. Miguel Silva", Morelia, Mexico
- Ayala, Daniel Enrique, Hospital General "Dr. Miguel Silva", Morelia, Mexico
- Vazquez Avila, Armando, Hospital General "Dr. Miguel Silva", Morelia, Mexico
- Arellano, Jesus, Hospital General "Dr. Miguel Silva", Morelia, Mexico
- Mariscal, Luis A., NausLife Hemodialysis Clinics, Morelia, Michoacán, Mexico
- Gomez, Victor H., Hospital General "Dr. Miguel Silva", Morelia, Mexico
- Campos, Israel, NausLife Hemodialysis Clinics, Morelia, Michoacán, Mexico
Background
Intra-dialytic exercise (IDE) improves cardiovascular function, physical function and quality of life. Arterial (SaO2) and central venous oxygen saturation (ScvO2) can be measured during hemodialysis (HD). The oxygen extraction ratio (OER) is the result from: SaO2-ScvO2/SaO2; its increment during HD has been associated with a higher mortality. The aim of this study was to explore the acute effects of IDE on SaO2, ScvO2 and OER.
Methods
Crossover study in maintenance adult HD patients. The ScvO2 by gas analyzer and SaO2 by pulse-oximetry were measured at 0, 60, 120 and 180 minutes during one HD treatment without IDE, same measurements were repeated in one HD treatment with IDE. The SaO2, ScvO2 and OER were compared at each time point and between treatments.
Results
11 patients (22 HD treatments) were analyzed. The ScvO2 and OER trend during HD with and without IDE are reported (Figure 1). The ScvO2 median (P25, P75) with vs without IDE at 60 and 120 min were 59(55, 62.5) vs 69(65, 73) p=0.005; and 57(50.5, 64.5) vs 66(62, 69.5) p=0.04, respectively. OER median (P25, P75) with vs without IDE at 60 and 120 min were 0.39(0.36, 0.43) vs 0.28(0.22, 0.32) p=0.005, and 0.41(0.43, 0.48) vs 0.33(0.25, 0.37) p=0.05, respectively, no differences were found in SaO2.
Conclusion
The ScvO2 decreases during HD, this decline is deeper during IDE compare to non-exercise treatments. OER increases during HD and is higher during IDE compare to non-exercise treatments. Further studies are required to elucidate the oxygen dynamics during intra-dialytic exercise.