Kidney Week

Abstract: SA-PO1066

Impact of Patient Awareness and Age on Serum Albumin in Chronic Hemodialysis Patients

Session Information

• Diet and Nutrition: Clinical
  October 27, 2018 | Location: Exhibit Hall, San Diego Convention Center
  Abstract Time: 10:00 AM - 12:00 PM

Category: Health Maintenance, Nutrition, and Metabolism

• 1302 Health Maintenance, Nutrition, and Metabolism: Clinical

Authors

• Alanazi, Shehabaldeen Mohammed, DaVita-Saudi Arabia, Riyadh, Saudi Arabia

Shehabaldeen Mohammed Alanazi,

• Abderrahim, Ezzedine, DaVita-Saudi Arabia, Riyadh, Saudi Arabia

Ezzedine Abderrahim,

• Al-Badr, Wisam H.A., DaVita-Saudi Arabia, Riyadh, Saudi Arabia

Wisam H.A. Al-Badr,

• Alsuwaida, Abdulkareem, DaVita-Saudi Arabia, Riyadh, Saudi Arabia

Abdulkareem Alsuwaida,

• Abdulaziz, Suad, DaVita-Saudi Arabia, Riyadh, Saudi Arabia

Suad Abdulaziz,

• Shams, Amani Mohammed, DaVita-Saudi Arabia, Riyadh, Saudi Arabia

Amani Mohammed Shams,

• Albalbisi, Riham Adnan, DaVita-Saudi Arabia, Riyadh, Saudi Arabia

Riham Adnan Albalbisi,

• Alobaili, Saad S., DaVita-Saudi Arabia, Riyadh, Saudi Arabia

Saad S. Alobaili,

• Jubran, Ibrahim Abduh, DaVita-Saudi Arabia, Riyadh, Saudi Arabia

Ibrahim Abduh Jubran,

• Kashgary, Abdullah, DaVita-Saudi Arabia, Riyadh, Saudi Arabia

Abdullah Kashgary,

Background

Hypoalbuminemia is associated with cardiovascular death in patients on maintenance hemodialysis (HD) and is a marker of malnutrition–inflammation complex syndrome. In addition to dialysis adequacy, serum albumin is influenced by socioeconomic status and level of education and awareness regarding dietary requirements. The aim of our study was to identify potential factors determining hypoalbuminemia in population of prevalent HD patients in Saudi Arabia.

Methods

The study included 372 prevalent patients receiving maintenance HD at DaVita-KSA (215 female, 157 male). Mean age was 54.4 ± 17.2 years. The study population was divided into two groups based on serum albumin recorded in Feb 2018 (G1: ≤3.5 g/dL, G2: >3.5 g/dL) and parameters of socioeconomic status, food preparation/intake, and dialysis adequacy were assessed. We performed multiple logistic regression analysis to identify parameters that were independently associated with serum albumin level.

Results

There were 160 patients in G1 and 212 in G2 with no significant difference between males and females. In univariate analysis, factors found to be associated with hypoalbuminemia were: old age, low level of education, diabetes, short ESRD duration and lack of diet awareness. Patients in G2 had higher levels of serum creatinine, potassium, phosphorus, nPCR, and hemoglobin, and greater gain in dry weight. There were no significant differences between groups with respect to other socioeconomic factors or food intake. Multivariate analysis revealed that old age (RR: 1.032/year; 95% CI [1.017-1.047]) and diet awareness (RR: 1.2; 95% CI [1.0.2-1.36]), were independent predictors of hypoalbuminemia.

Conclusion

In our study, hypoalbuminemia correlated with age and level of diet compliance, which itself is determined by the education level of HD patients. Lower serum albumin is also associated with weight loss without correlation with monthly income or other socioeconomic factors.

Funding

• Commercial Support – DaVita