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Journal Club

Thursday, December 5, 2024 | 4:00 PM – 5:00 PM ET

Hosted by the American Society of Nephrology

Featured article: A Randomized Trial of Intravenous Amino Acids for Kidney Protection

N Engl J Med 2024;391:687-698 | doi: 10.1056/NEJMoa2403769 | Published June 12, 2024 | Vol. 391 No.8

In this article:

Acute kidney injury (AKI) is a serious and common complication of cardiac surgery, for which reduced kidney perfusion is a key contributing factor. Intravenous amino acids increase kidney perfusion and recruit renal functional reserve. However, the efficacy of amino acids in reducing the occurrence of AKI after cardiac surgery is uncertain. In a multinational, double-blind trial, the authors randomly assigned adult patients who were scheduled to undergo cardiac surgery with cardiopulmonary bypass to receive an intravenous infusion of either a balanced mixture of amino acids, at a dose of 2 g per kilogram of ideal body weight per day, or placebo (Ringer's solution) for up to 3 days. Attend this Journal Club to learn the outcome of this research. 

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Speaker

Rinaldo Bellomo AO




Co-Moderators

Amandeep Bajwa, PhD                      Associate Professor, College of Medicine              The University of Tennessee Health Science Center

Mark D. Okusa, MD, FASN                     John C. Buchanan Distinguished Professor of Medicine: Nephrology              University of Virginia School of Medicine




Questions?

If you have questions about this webinar, please contact Bonnie Freshly, Senior Project Specialist for Excellence in Patient Care, at bfreshly@asn-online.org.


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