RE: KFRE 3 minutes ago

Thanks prof . How you explain risk to patient is. More than 5 out of 100 is increased risk ? --------------------------------- Muhammad Soobada...

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RE: Case 15 minutes ago

Creatine 0.8 eGFR 90 --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------

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RE: Renal Biopsy Post Plex 18 minutes ago

After plex how long need to wait before taking bloods for anti-gbm titre? And after dialysis? --------------------------------- Muhammad Soobad...

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RE: Renal Biopsy Post Plex 19 minutes ago

Wcc was 8 before cyclo is now 5 --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------

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RE: a Puzzling case 48 minutes ago

This patient needs a measured GFR . He may have a " 'shrunken pore syndrome ". ------------------------------ Richard Glassock MD, FASN Laguna Wo...

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RE: cystatin C gfr 4 hours ago

The Shrunken Pore Syndrome (SPS) is a hypothesis originally developed by Grubb and Colleagues (see GrubbA. Clinical Biochemustry , 2020 ; 83 :12-20...

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RE: Dialysis Consent 6 hours ago

1) We do require consent but it lasts for a year, that was a compromise the last time we went to our hospital's Risk Management 2) separate g...

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RE: cystatin C gfr 7 hours ago

I am also not a Cystatin C enthusiast. There are a couple of situations where it might be helpful, but not routinely. The eGFR (and the cystatin C)...

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Dialysis Consent 9 hours ago

Hi all, I am curious about need for consents for dialysis in the hospital for patients on dialysis. 1) Do you require consents for continuing di...

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RE: cystatin C gfr 10 hours ago

Thank you very much sir for your response can you elaborate a bit more on the SPS - its patho genesis perhpas and its relevance for us in clin...

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KDIGO-2025 guidelines for renal anemia, now available as draft 10 hours ago

Dear colleagues, a draft of the 2025 KDIGO guidelines on renal anemia is available (see attached with some comments of mine) and open for comments...

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RE: cystatin C gfr 16 hours ago

When eGFR -creatinine is "stable " and eGFR-Cystatin C is "declining" how do you know which one of the two estimates is giving the "correct" pictur...

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RE: cystatin C gfr 20 hours ago

I am not a Cystatin C enthusiast. It has limited value and should be used when indicated, not as a routine. The biggest drawback is that there is n...

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RE: a Puzzling case 21 hours ago

I would do a 24 hour urine for creatinine clearance and a cystatin -creatinine eGFR. There are several issues with cystatin C measured GFR which wi...

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RE: Ac proliferative GN w IC deposits 23 hours ago

I agree fully with Dr. Rodby. Not really full-house Nephropathy. Needs more serology, including Rheumatoid Factor, HCV, HBV. If she proves to have ...

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RE: Ac proliferative GN w IC deposits 1 day ago

the post above you looks almost identical! https://community.asn-online.org/discussion/non-lupus-full-house-crescenteric-gn-managment-question...

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RE: Non-Lupus Full house Crescenteric GN managment question 1 day ago

can you post a deintintified biopsy reading? non-lupus full house GN may have a worse prognosis than lupus full house GN See attached) Woul...

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Non-Lupus Full house Crescenteric GN managment question 1 day ago

Dear All. I need group help to manage this interesting but confusing case. 26 years old lady with BMI 39 and history of migraine and normal k...

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Ac proliferative GN w IC deposits 1 day ago

Hello everyone, I have a 49 year young caucasian woman, nurse by profession, who was ref to me for proteinuria. PCP noticed it 6m ago and I was ...

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RE: Management In ADTKD 1 day ago

Since new nephrons cannot be generated by this approach, any increase in GFR would likely be due to worsening single nephron hyperfiltration . This...

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RE: Management In ADTKD 1 day ago

You are welcome. Due to the novelty and potential for the approach, we might be able to lobby the company to provide the 3 month therapy for free. ...

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RE: Requesting advice on IgA nephropathy patient 1 day ago

Thanks so much for all the ideas, I have a much better plan of how to present this to him. ------------------------------ Jayson L. Yap, MD Renal...

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RE: Collapsing FSGS 1 day ago

Was she tested for COViD during either episode of AKI/NS? Do you have EM results on kidney biopsy, any tubulo-reticular inclusions (TRI)? Was she t...

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RE: A case of C3GN 1 day ago

" The deposits are variable in Lshape and position, including mesangial deposits, paramesangial, intramembranous, and subepithelial deposits resemb...

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RE: Requesting advice on IgA nephropathy patient 1 day ago

Dear dr Glassock , Would you start MMF after 2 months of steroids ? And for how long will keep on MMF ? thanks ----------------------------...

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RE: Requesting advice on IgA nephropathy patient 1 day ago

Interesting idea but no studies have ever been performed to study the question. I would be concerned that the two drugs taken together (or sequenti...

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RE: A case of C3GN 1 day ago

Interesting case for which I have no insightful answers but rather additional ques have u sent gentic testing for compl disorders assoc with C3...

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RE: A case of C3GN 1 day ago

Dr Venkat - Thanks for pointing out the typo regarding the proteinuria- I have corrected it. The EM findings consistent with c3 gn per report- I...

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Collapsing FSGS 1 day ago

Dear Colleagues, I'd be grateful for your opinions Patient is a 30 year old lady of West African origin with tablet controlled type 2 Diabetes....

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RE: hereditary nephropathy? 1 day ago

With family history of renal failure, predominantly mesangial lesion, no immune deposits on IF. This could be Type III Collagen Glomerulopathy or F...

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RE: Requesting advice on IgA nephropathy patient 1 day ago

I think that oral methylprednisolone and oral controlled released budesonide have different site of action and it is like combing diltiazem with am...

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RE: Requesting advice on IgA nephropathy patient 1 day ago

In the presence of hematuria and glomerular inflammation I think that Oral prednisone followed by MMF maintenance therapy are good choices. No comp...

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RE: hereditary nephropathy? 1 day ago

Unfortunately, without EM or genetic studies it will be very difficult, if not impossible., to determine a diagnosis. in this patient, The IF seems...

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RE: Requesting advice on IgA nephropathy patient 1 day ago

I have similar patient few months age with similar MESTC score. Baseline Cr was 2 and UPCR 1 g/g My plan was: Methylprednisolone 32 mg for 2 months...

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RE: Requesting advice on IgA nephropathy patient 1 day ago

Totally agree with Dr. Rodby and I would start now with low dose methylprednisolone plus budesonide. Switch to sparsentan and also add finerenone. ...

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RE: Requesting advice on IgA nephropathy patient 1 day ago

My choice for this patient is moderate dose oral steroids for 2 months (TESTING II protocol) followed by MMF for Maintenance, ifca responses in hem...

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RE: Requesting advice on IgA nephropathy patient 1 day ago

I do agree with Dr Roddy about anti April or anti April plus anti baff class of drugs My issue is how do u convince a pt to choose placebo contro...

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RE: A case of C3GN 1 day ago

Dr. Paramasivam: If I am reading your post correctly, UPr/Cr has already decreased from 6.24 g/g to 3.9 g/g, SCr from 1.5 to 1.29 mg and (important...

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RE: hereditary nephropathy? 2 days ago

There are no skin lesions ------------------------------ Zineb Taaam MD Centre hospitalier universitaire Mohammed VI Oujda, Morocco +21266670870...

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RE: hereditary nephropathy? 2 days ago

Thank you very much for your responses. The C3 is at 0.7, with normal values ranging from 0.75 to 1.75. Unfortunately, the genetic study is not...

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A case of C3GN 2 days ago

36 y.o. male with a past medical history of alcohol use disorder in remission, ankle fracture s/p recent ORIF in June who presented with increased ...

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RE: hereditary nephropathy? 2 days ago

Confusing that C3 is low and no deposits seen on IF. I'd probably repeat both of those (recut and stain IF sections) to be sure. Any skin lesions? ...

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RE: hereditary nephropathy? 2 days ago

"Creatinine: 350 µmol/L" In a 15-year-old female, this indicates advanced CKD. With a low GFR, proteinuria may have decreased from a previously h...

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RE: hereditary nephropathy? 2 days ago

I assume this is all tubulointerstitial diseased that the majority of the urine protein is not albumin, you could check the simultaneous urine prot...

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hereditary nephropathy? 2 days ago

Hello to the entire community, I would like to request your opinion regarding a young patient. Ms. M is a 15-year-old patient with no significa...

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RE: cystatin C gfr 2 days ago

I find it occasionally useful but not as a routine test. By coincidence I read this post just after seeing one of the few patients where I have use...

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RE: Management In ADTKD 2 days ago

Dr Meanaway very interesting Thanks for your expert opinion --------------------------------- Shahzad Safdar MD MD Mt. Auburn Nephrology, Inc...

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RE: Psoriasis and IgA nephropathy 2 days ago

So ; I totally agree with you. The question in mind arose for possible secondary IgA in setting of psoriasis and possible exclusion of this group ...

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RE: a Puzzling case 2 days ago

Hypothyroidism generally decreases and hyperthyroidism increases cystatin C levels. Obesity and steroids increase cystatin C. Inflammation increase...

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RE: Psoriasis and IgA nephropathy 2 days ago

All the more reason to use an anti-inflammatory approach. ------------------------------ Richard Glassock MD, FASN Laguna Woods CA (949) 388-8885...

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