RE: Case 1 hour ago

You are missing out on a useful diagnostic test. Too bad. ------------------------------ Richard Glassock MD, FASN Laguna Woods CA (949) 388-88...

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RE: Very High risk membranous 1 hour ago

What was his response to RTX previously? The relapse of severe Nephrotic Syndrime after cessation of CNI is not surprising. Cyclical CYC, in usual ...

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RE: Terlipressin 3 hours ago

Its a good tool to have at your disposal. Reliably increases MAP without need for ICU and inotropes, which is great in busy hospitals. Reverses HRS...

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RE: cystatin C gfr 3 hours ago

amazing discussion and good reminders of the actual factors that need to be focused on ty all for enriching the discussion -------------------...

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RE: Ac proliferative GN w IC deposits 3 hours ago

This is an ICGN, probably auto-immune (she has Hashimoto's disease and auto-immune diseases itend to occur together), possibly C3GN. Please add C3 ...

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RE: Ac proliferative GN w IC deposits 4 hours ago

Dr Rodby. Please see the LM below Dr Glassock - She DOES have breast cancer but its localized enough to warrant ONLY lumpectomy - no chemo, no...

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RE: Case 5 hours ago

Thanks prof. We don’t spin urine in England UK unfortunately . So I would not know Bw --------------------------------- Muhammad Soobadar MBChB...

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Very High risk membranous 10 hours ago

Dear Colleagues I need your expert opinion on this case: 40 y old, male, Known Membranous nephropathy. treated with RTX and he was on cyclos...

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RE: Terlipressin 16 hours ago

Thanks. Understood. The reason I asked is that some believe that Terlipressin can also be used in septic shock, resistant to nor-epinephrine. --...

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RE: Terlipressin 17 hours ago

ADH = Vasopressin We have experience with Vasopressin use in CCU: usually not the first choice in shock states. Vasopressin use is very tricky; y...

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RE: Requesting advice on IgA nephropathy patient 20 hours ago

I am not aware of registry of steroid induced avascular necrosis of Hip or major joint. Of severe side effects. Does anyone know that such registry...

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RE: Renal Biopsy Post Plex 20 hours ago

Dialysis has no effect on anti-GBM antibody levels. The best time to measure anti-GBM antibody levels is immediately before starting a session of P...

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RE: Terlipressin 20 hours ago

In what Disease states do you plan to use Terlipressin? ------------------------------ Richard Glassock MD, FASN Laguna Woods CA (949) 388-8885 ...

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RE: Requesting advice on IgA nephropathy patient 20 hours ago

What is the basis of the claim that the "side effects " of TRF-Budesonide are much less than those seen with moderate doses of oral methylprednisol...

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Terlipressin 20 hours ago

Dear Colleagues- We are trying to add Terlipressin to our formulary drug list. Would like to know from the group about their experience with Terlip...

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RE: Case 20 hours ago

What is the microscopic appearance of the RBC in urine. If dysmorphic, I would do a kidney biopsy, if the patient consents, --------------------...

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RE: Requesting advice on IgA nephropathy patient 20 hours ago

True that Peyer's are not necessarily the site of IgA1 production in all patients not these lymphocytes will be sensitive to budesonide. However, t...

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RE: KFRE 20 hours ago

I woukd say that his risk of developing ESKD at some point in his expected lifetime is likely higher than a healthy individual with two kidneys, bu...

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TERLIPRESSIN IN HRS 20 hours ago

Hello We are trying to add Terlipressin to our formulary drug list. Would like to know from the group about their experience with Terlipressin an...

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RE: cystatin C gfr 20 hours ago

Cystatin-C is being wrongfully touted as accurate, this is not true. In addition to pore size, cystatin-c production is controlled by large number ...

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RE: KFRE 21 hours ago

Thanks prof . How you explain risk to patient is. More than 5 out of 100 is increased risk ? --------------------------------- Muhammad Soobada...

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RE: Case 21 hours ago

Creatine 0.8 eGFR 90 --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------

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RE: Renal Biopsy Post Plex 21 hours ago

After plex how long need to wait before taking bloods for anti-gbm titre? And after dialysis? --------------------------------- Muhammad Soobad...

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RE: Renal Biopsy Post Plex 21 hours ago

Wcc was 8 before cyclo is now 5 --------------------------------- Muhammad Soobadar MBChB UK ---------------------------------

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RE: a Puzzling case 21 hours ago

This patient needs a measured GFR . He may have a " 'shrunken pore syndrome ". ------------------------------ Richard Glassock MD, FASN Laguna Wo...

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RE: cystatin C gfr 1 day ago

The Shrunken Pore Syndrome (SPS) is a hypothesis originally developed by Grubb and Colleagues (see GrubbA. Clinical Biochemustry , 2020 ; 83 :12-20...

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RE: Dialysis Consent 1 day ago

1) We do require consent but it lasts for a year, that was a compromise the last time we went to our hospital's Risk Management 2) separate g...

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RE: cystatin C gfr 1 day ago

I am also not a Cystatin C enthusiast. There are a couple of situations where it might be helpful, but not routinely. The eGFR (and the cystatin C)...

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Dialysis Consent 1 day ago

Hi all, I am curious about need for consents for dialysis in the hospital for patients on dialysis. 1) Do you require consents for continuing di...

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RE: cystatin C gfr 1 day ago

Thank you very much sir for your response can you elaborate a bit more on the SPS - its patho genesis perhpas and its relevance for us in clin...

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KDIGO-2025 guidelines for renal anemia, now available as draft 1 day ago

Dear colleagues, a draft of the 2025 KDIGO guidelines on renal anemia is available (see attached with some comments of mine) and open for comments...

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RE: cystatin C gfr 1 day ago

When eGFR -creatinine is "stable " and eGFR-Cystatin C is "declining" how do you know which one of the two estimates is giving the "correct" pictur...

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RE: cystatin C gfr 1 day ago

I am not a Cystatin C enthusiast. It has limited value and should be used when indicated, not as a routine. The biggest drawback is that there is n...

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RE: a Puzzling case 1 day ago

I would do a 24 hour urine for creatinine clearance and a cystatin -creatinine eGFR. There are several issues with cystatin C measured GFR which wi...

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RE: Ac proliferative GN w IC deposits 1 day ago

I agree fully with Dr. Rodby. Not really full-house Nephropathy. Needs more serology, including Rheumatoid Factor, HCV, HBV. If she proves to have ...

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RE: Ac proliferative GN w IC deposits 1 day ago

the post above you looks almost identical! https://community.asn-online.org/discussion/non-lupus-full-house-crescenteric-gn-managment-question...

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RE: Non-Lupus Full house Crescenteric GN managment question 1 day ago

can you post a deintintified biopsy reading? non-lupus full house GN may have a worse prognosis than lupus full house GN See attached) Woul...

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Non-Lupus Full house Crescenteric GN managment question 1 day ago

Dear All. I need group help to manage this interesting but confusing case. 26 years old lady with BMI 39 and history of migraine and normal k...

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Ac proliferative GN w IC deposits 2 days ago

Hello everyone, I have a 49 year young caucasian woman, nurse by profession, who was ref to me for proteinuria. PCP noticed it 6m ago and I was ...

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RE: Management In ADTKD 2 days ago

Since new nephrons cannot be generated by this approach, any increase in GFR would likely be due to worsening single nephron hyperfiltration . This...

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RE: Management In ADTKD 2 days ago

You are welcome. Due to the novelty and potential for the approach, we might be able to lobby the company to provide the 3 month therapy for free. ...

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RE: Requesting advice on IgA nephropathy patient 2 days ago

Thanks so much for all the ideas, I have a much better plan of how to present this to him. ------------------------------ Jayson L. Yap, MD Renal...

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RE: Collapsing FSGS 2 days ago

Was she tested for COViD during either episode of AKI/NS? Do you have EM results on kidney biopsy, any tubulo-reticular inclusions (TRI)? Was she t...

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RE: A case of C3GN 2 days ago

" The deposits are variable in Lshape and position, including mesangial deposits, paramesangial, intramembranous, and subepithelial deposits resemb...

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RE: Requesting advice on IgA nephropathy patient 2 days ago

Dear dr Glassock , Would you start MMF after 2 months of steroids ? And for how long will keep on MMF ? thanks ----------------------------...

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RE: Requesting advice on IgA nephropathy patient 2 days ago

Interesting idea but no studies have ever been performed to study the question. I would be concerned that the two drugs taken together (or sequenti...

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RE: A case of C3GN 2 days ago

Interesting case for which I have no insightful answers but rather additional ques have u sent gentic testing for compl disorders assoc with C3...

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RE: A case of C3GN 2 days ago

Dr Venkat - Thanks for pointing out the typo regarding the proteinuria- I have corrected it. The EM findings consistent with c3 gn per report- I...

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Collapsing FSGS 2 days ago

Dear Colleagues, I'd be grateful for your opinions Patient is a 30 year old lady of West African origin with tablet controlled type 2 Diabetes....

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RE: hereditary nephropathy? 2 days ago

With family history of renal failure, predominantly mesangial lesion, no immune deposits on IF. This could be Type III Collagen Glomerulopathy or F...

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