ASN represents more than 21,000 kidney health professionals working to help people with kidney diseases and their families. Comprised of all of ASN's focus areas, the ASN Alliance for Kidney Health allows the society to continue its growth and work towards the goal of a world without kidney diseases.
The latest Nephrology Self-Assessment Program (nephSAP) issue, Volume 23: Issue 4 (Oct 2024): Chronic Kidney Disease is now available online.
RE: IgA Nephropathy 3 minutes ago
Dr glassock you are right about that and I also want to mention that I met a 25 year old female pt ( height 4feet 10 in ) recently at Igan workshop...
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RE: Need advice on Membranous Nephropathy with Ext-2 47 minutes ago
I will treat with RAASI plus glucose transport inhibitors for 3 months if proteinuria worsens then mmf or rituximab can be considered. Just an opin...
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RE: Need advice on Membranous Nephropathy with Ext-2 53 minutes ago
Here is more details: -No TRI, IF shows granular capillary wall staining IgG (3+), C3 (1+), kappa (3+), and lambda (3+). Other stains are negativ...
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RE: IgA Nephropathy 1 hour ago
Thank you Dr Glassock and everyone for all the wonderful remarks. I will discuss with the patient and probably suggest TRF Budenoside as a reasonab...
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Is this inherited glomerulonephritis, and, if so, which? 1 hour ago
Dear experts, may I please have your oppinion on this case: 56 year, female English teacher from Syria - microhematuria since childhood; now conf...
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RE: Need advice on Membranous Nephropathy with Ext-2 1 hour ago
Just curious why did you do Exotin staining in absence clinical evidence of autoimmune disease What did IF show? Non lupus full house picture has b...
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RE: Diagnosis of ADPKD 1 hour ago
Indeed, it's not Mayo class 1, but 2. So, the Mayo ADPKD Calculator (one of the best achievments in medicine!) is not applicable for prognosis pred...
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RE: Need advice on Membranous Nephropathy with Ext-2 1 hour ago
Dr. Solanki- just curious, On what basis did you select a regimen of high dose methyl prednisolone (MP, ?IV) combined with such a low dose of RTX f...
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RE: Starting SLT2 inhibitor with asymptomatic UTI/colonization? 1 hour ago
Difficult to provide an evidence based answer. The data, so far, indicate a very low risk of harm in such patients with asymptomatic bacteruria. Ho...
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RE: IgA Nephropathy 2 hours ago
Understood, but you nay be biased in your experience because of the use of HIGH rather than MODERATE dose oral steroids. If you or the patient are ...
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RE: Starting SLT2 inhibitor with asymptomatic UTI/colonization? 2 hours ago
Yes, it's a difficult question to answer. Therefore, I am placing on this international forum of experts. On one hand, SGLT2 inhibitors are benefic...
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RE: post kidney transplant TMA 2 hours ago
You are stuck between a Rock and a Hard Place- A old proverb indicating a dilemma. I would restart PLEX and give IVIgG and hope for the best, but e...
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RE: Starting SLT2 inhibitor with asymptomatic UTI/colonization? 2 hours ago
Does asymptomatic bacteruria increase the risk if symptomatic UTI after starting SGLT2i in a diabetic with 'incipient" Nephropathy. I do not know t...
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RE: post kidney transplant TMA 2 hours ago
Prednisolone and MMF Iptacopan is not available over here ------------------------------ Bee Boon Cheak; MD Ministry of Health, Malaysia -------...
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RE: post kidney transplant TMA 3 hours ago
What immunosupreive therapy did you switch to ? I would avoid Cyclosporine or Mtor as both could also trigger endothelial damage and induce TMA . C...
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Starting SLT2 inhibitor with asymptomatic UTI/colonization? 3 hours ago
Gentleman age 68 with Diabetes type II insulin requiring and last A1c rising to 7.5 in July, 2024. GFR stable at 77. Potassium 3.9. Magnesium 1.5...
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RE: IgA Nephropathy 4 hours ago
You are correct about prednisone but over time I have developed aversion to systemic steroids ( esp if I have other options ) because of adverse ev...
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RE: IgA Nephropathy 4 hours ago
Thank you all for the insights! I’m definitely leaning towards treatment. --------------------------------- Eithan Orlev-Shitrit MD MONTGOMERY ...
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RE: post kidney transplant TMA 5 hours ago
Eculizumab is very likely the best therapy for de novo TMA developing post living unrelated ABO incompatible donor transplant . If it is available ...
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RE: Need advice on Membranous Nephropathy with Ext-2 5 hours ago
We have a similar patient Pt 56 year /M , with strong H/O DM /Retinopathy presented with heavy proteinuria and severe hypoalbunemia ,and S.Cr in th...
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RE: IgA Nephropathy 5 hours ago
Why not oral systemic steroids in a moderate dose as an option as well, if TBMB is excluded by EM analysis? No direct comparator studies for TRF -B...
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RE: Need advice on Membranous Nephropathy with Ext-2 5 hours ago
Interesting anecdote. It would be if interest to have Dr. Ismail share additional data concerning the IF and EM of his patient with EXTI/II + MN. A...
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RE: Need advice on Membranous Nephropathy with Ext-2 6 hours ago
I have a similar pt was treated with ritux twice in 3 years in PR , moved to FL SLE w/u eventually became positive after so many years . -------...
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RE: IgA Nephropathy 6 hours ago
Hematturia is not benign finding any longer . There is a thought process that suppressing proteinuria with arb and sglt2 etc does not treat igA (...
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post kidney transplant TMA 8 hours ago
I have a patient with unknown primary disease who underwent living related kidney transplant, with donor being the spouse. ABOi and as per standard...
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RE: EuroLupus Protocol in patient with eGFR 20 11 hours ago
Hi Dr Glassock, I have not seen the NIH IV CYC being prescribed before. But I did note KDIGO guideline mentioned IV CYC 0.5-1mg/m2 monthly und...
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RE: EuroLupus Protocol in patient with eGFR 20 12 hours ago
Thank you Dr Prajapati for your input / advice. ------------------------------ Siev Hong Lor PharmD Pharmacist Liverpool Hospital, NSW E: hong...
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RE: IgA Nephropathy 12 hours ago
In our observational study of IgAN only about 14% of those with hematuria at BL did not have an M1 lesion by KB.See Bobart S, et al, NDT, 2019. -...
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RE: IgA Nephropathy 13 hours ago
Thank you very much Dr Glassock. TBMN is an interesting option I did not think of. --------------------------------- Eithan Orlev-Shitrit MD MON...
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RE: Diagnosis of ADPKD 16 hours ago
Since this patient very likely does not have ADPKD, then the Mayo Classification system is NOT applicable. Tolvaptan is not indicated. See Dr. Cheb...
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RE: Diagnosis of ADPKD 19 hours ago
Thanks . Would mayo apply here ? Its seems atypical isn’t ? Not diffuse cystic nature in kidneys --------------------------------- Muhammad Soob...
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RE: IgA Nephropathy 19 hours ago
I agree! - no good evidence to support use if TRF Budesonide in this case, . But if prescribed it would be 'on label" as the FDA does not specify a...
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RE: IgA Nephropathy 22 hours ago
Thank you very much Dr Rodby ! Given the lack of improvement in hematuria / proteinuria and her age I was considering Budenoside with the main con...
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RE: IgA Nephropathy 1 day ago
Hematuria is now considered by some to be a predictor of poor outcome bc it is the sign of inflammation something not really dont see in this bi...
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RE: Need advice on Membranous Nephropathy with Ext-2 1 day ago
Thank you for prompt response. he doesn't have any autoimmune features, and extended antibody panels were negative. Biopsy didn't show diabetic f...
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IgA Nephropathy 1 day ago
I’m treating for the past 9 month a 33 y/F that presented to me with 2 years of Hematuria. K biopsy revealed: Diagnosis: IgA nephropathy LM: On...
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RE: MCGN 1 day ago
very odd that he is so steroid responsive yet did not respond to rituximab. Obi is a good idea as suggested by Dr Glassock, but if you cannot...
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RE: Case of Interstitial Nephritis 1 day ago
If it wasn’t for the hypotension (& negative serologies), I would have honed in on the pre-glomerular vasculopathy (rather than the interstitial ne...
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RE: Need advice on Membranous Nephropathy with Ext-2 1 day ago
not really nephrotic Exostocin MGN is supposed to have a better prognosis I generally think most MGNs regardless of the antibody should be tre...
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RE: Need advice on Membranous Nephropathy with Ext-2 1 day ago
EXTI/II MN is usually associated with lupus like auto.immune features, but this might be an exceptional case. The prognosis is usually favorable , ...
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RE: Case of Interstitial Nephritis 1 day ago
The striking features in this case are hypokalemia, intermittent hypercalcemia, low BP and vascular lesions (resembling " hypertensive" microangiop...
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Need advice on Membranous Nephropathy with Ext-2 1 day ago
I have a 63 year old male with diabetes (A1c 6.5), hypertension, OSA, CAD and obesity referred by his PCP for worsening proteinuria and worsen edem...
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RE: Case of Interstitial Nephritis 1 day ago
We had a case a year ago of a young patient with Cr of 5 on routine check (didn't take any meds), biopsied them, had chronic interstitial nephritis...
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RE: MCGN 1 day ago
He seems to be a good candidate for Obinutuzumab. ------------------------------ Richard Glassock MD, FASN Laguna Woods CA (949) 388-8885 -------...
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RE: Case of Interstitial Nephritis 1 day ago
Is metabolic alkalosis present. I would measure PRA and serum aldosterone. ------------------------------ Richard Glassock MD, FASN Laguna Woods ...
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RE: 2nd Annual UME Educator Kidney Week Meetup 1 day ago
Thank you for the email. I do teach MS1 renal block. However, I am unable to attend ASN this year! Gurwant Kaur Penn State Get Outlook for iOS
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RE: 2nd Annual UME Educator Kidney Week Meetup 1 day ago
Thank you. Will be there !! Kartik Kalra ------------------------------ Kartik Kalra MD, FASN Geisinger Health Danville PA (908) 583-4534 ----...
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MCGN 1 day ago
I have a 22 year old morbidly obese patient who i saw originally in 2022 when he presented with a full blown nephrotic syndrome with a urine protei...
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RE: Potential donor with probable BORSD 1 day ago
There is another concern of mother have low renal reserve from halpo-insufficiency of EYA1 leading to delay in nephrogenesis by depleting stem cell...
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RE: Case of Interstitial Nephritis 1 day ago
do you have a simultaneous PCR to the ACR? looking for degree of tubular proteinuria What is his "race"? wondering about APOL1 but his LOW BP arg...
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