RE: Teriflunomide / Leflunomide TDM 5 hours ago

The questions that have not been adequately addressed, in my opinion is 1) whether the failure of Leflunomide therapy for BK viremia is an intrinsi...

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RE: Late /wrong referrals of CKD patients 5 hours ago

In my opinion, the first task is to define and identify the clinical and laboratory characteristics of AVOIDABLE UNTIMELY referrals from Primary Ca...

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Late /wrong referrals of CKD patients 16 hours ago

Good afternoon I joined a post-graduation about Safety, Quality, Informatics and Leadership at Harvard Medical School, and my capstone project is...

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RE: Nephrotic Syndrome And Pregnancy 18 hours ago

Dr. Rodby is correct in saying that LN class-5 vs lupus podocytopathy is a difficult distinction to make without a biopsy. However, if severe nephr...

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RE: Nephrotic Syndrome And Pregnancy 19 hours ago

I dont think there is a way to distinguish Class V from a solitary podocytopathy clinically. The former is more common and I would suspect this ...

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RE: Teriflunomide / Leflunomide TDM 20 hours ago

Hi , recent studies have not shows any effect of leflunomide or ciprofloxacine on BK viremia or BK nephropathy , careful reduction of IS is the sta...

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RE: Nephrotic Syndrome And Pregnancy 20 hours ago

If this severe nephrotic syndrome developed abruptly/suddenly, agree with Dr. Glassock that lupus podocytopathy is a strong possibility. -----...

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RE: Nephrotic Syndrome And Pregnancy 1 day ago

Thank you Dr for sharing this interesting case I think it's better to postponed the kidney biopsy since she has normal RFT and she is 23 weeks of...

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Nephrotic Syndrome And Pregnancy 1 day ago

A healthy 26 year old Hispanic lady, referred to our office for nephrotic syndrome- she s currently 23 weeks pregnant- started to have swelling aro...

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RE: Teriflunomide / Leflunomide TDM 1 day ago

I could find only one reference to your question. See Nesselhauf N, et al.J Nephropathol 2015; 5:34-37 (Open Access). I hope this helps. ------...

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RE: AKI/CKD of unknown etiology 1 day ago

Thank you for the response, Dr Rodby. I actually did not repeat the urine micoalbumin/creatinine and protein/creatinine ratio (was checked in the...

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RE: Teriflunomide / Leflunomide TDM 1 day ago

Sorry. I omitted to say, leflunomide is prescribed in the setting of renal transplant recipient with history of BK viraemia. --------------------...

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RE: AKI/CKD of unknown etiology 1 day ago

"No proteinuria" remember dipstick only picks up albuminuria, would probably do a urine protein/Cr ratio and urine albumin/Cr ratio, see if ther...

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AKI/CKD of unknown etiology 1 day ago

I have a delightful 58 y.o. female with a history of GERD x 30 years (was on PPI and now on H2 blocker), GAD, prior episode of shingles and underly...

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RE: PGNMID 1 day ago

If you can start with dara I would, (from attached) "In conclusion, this study supports and extends the recently reported prospective cl...

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RE: KFRE 1 day ago

I think you have to look at patient's age, BP before and after, creatinine before and after, and proteinuria before and after. If there is ANY e...

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RE: Renal Biopsy Post Plex 1 day ago

We do all the plex in the hospital, and thrombocytopenia is extremely rare. WE replete with albumin unless coats are awry or we have a bleeding ris...

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RE: Renal Biopsy Post Plex 1 day ago

PLEX may remove platelets and cause thrombocytopenia. Obviously, this might increase risk of post-biopsy bleeding. Fortunately, this complication o...

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POCUS training in nephrology - position statement 1 day ago

Dear Nephrology Educators, Attached is a position statement on multi-organ POCUS training in nephrology, co-authored by 21 educators from 12 c...

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RE: KFRE 2 days ago

KFRE is only valid in CKD stage 3A -5. ------------------------------ Richard Glassock MD, FASN Laguna Woods CA (949) 388-8885 ------------------...

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RE: Renal Biopsy Post Plex 2 days ago

Octoplas as replacement fluid for PLEX should reduce the risk of bleeding after Kidney Biopsy, compared to 5% albumin replacement fluid for PLEX. ...

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RE: PGNMID 2 days ago

I think you should complete your search for a clone with a bone marrow biopsy and if enlarged Lymph Norse are found on exam or CT, these should be ...

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Renal Biopsy Post Plex 2 days ago

Is there any increased risk of bleeding in patient undergoing renal biopsy after plasma exchange with octoplas? Thanks

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PGNMID 2 days ago

Hello all, I would appreciate your thoughts on this patient. 31 year old female patient initially presented in 2019 with hematuria sub-nephrotic...

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RE: Teriflunomide / Leflunomide TDM 2 days ago

Interesting question. How strong is the evidence that any kind of TDM for teriflunomide or leflunomide improves outcome in RA or kidney disease. So...

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Teriflunomide / Leflunomide TDM 2 days ago

Hi all, Can I please get your insight and experience with teriflunomide / leflunomide TDM? So far I have gathered that the sample taken needed ...

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RE: KFRE 2 days ago

What is his eGFR and urine albumin now?When was the uninephrectomy performed? Do you happen to know his birthweight ? ---------------------------...

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RE: Access Issue With Recurrent Bactaeremia 2 days ago

I assume endocarditis has been looked for with a TEE. Ifyou are concerned about eptic thrombophlebitis as the source of recurrent Staph. aureus bac...

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RE: KFRE 2 days ago

Thanks prof glassock. This patient had renal cell cancer and right nephrectomy . --------------------------------- Muhammad Soobadar MBChB UK --...

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RE: KFRE 2 days ago

I do not think that this question has been studied, but I suspect that it would give an underestimate of true risk, but it would all depend on the ...

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RE: Access Issue With Recurrent Bactaeremia 2 days ago

If his cultures are currently negative you should proceed with fistula and make him take good care of it. History generally repeats itself and he i...

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RE: Apply today!! Travel Support Scholarship for Nephrology Fellows to attend Annual Dialysis Conference, Las Vegas 2025. 2 days ago

Hello ! In the attachment is my Case regarding complexities of managing dialysis in patients with mental health challenges and the unique int...

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RE: Access Issue With Recurrent Bactaeremia 2 days ago

Yes there was a line holiday before new tunnelled line was inserted . Blood cultures were negative before new line went in. Patient refuses to hav...

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KFRE 2 days ago

Is KFRE equation valid in patients with single kidney ? Bw

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RE: Access Issue With Recurrent Bactaeremia 3 days ago

was there a "line holiday" between lines? "He has agreed to have line out 5 days post admission and is on iv flucoxacillin." looks like yes but I a...

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Access Issue With Recurrent Bactaeremia 3 days ago

Hi everyone , I have slightly challenging case in terms of vascular access and recurrent s aureus bactaeremia. 34 male previous failed transplant ...

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RE: Renal Artery Stenosis Case 3 days ago

I will find out about nsaid No Doppler but ct Angio Bw --------------------------------- Muhammad Soobadar MBChB UK -----------------------------...

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RE: resistant hypertension in hemodialysis patient even after bilateral renal embolization 3 days ago

Anass: 4 qstns: 1. how many Hrs of HD each time plz? Lengthening the time may be very helpful2. Is potential improvement in compliance entirely dep...

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RE: resistant hypertension in hemodialysis patient even after bilateral renal embolization 3 days ago

The BP was initially controlled then rose again. Reminds me of a case I had of a patient whose BP was controlled after surgical renal sympathecto...

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RE: igan nephropathy 3 days ago

AKI with gross hematuria following an URI in IgAN has been repeatedly described in the literature since the early 1980's. Most cases will spontaneo...

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RE: resistant hypertension in hemodialysis patient even after bilateral renal embolization 3 days ago

According to your records, on 12/03/2023 and on 27/03/2023 the patient underwent embolization of the left kidney. What was the indication for embol...

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RE: resistant hypertension in hemodialysis patient even after bilateral renal embolization 3 days ago

A few comments; a 20 yo female with ESKD with psychological/financial issues raises the question of medication compliance. Quite difficult for such...

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RE: resistant hypertension in hemodialysis patient even after bilateral renal embolization 3 days ago

The main cause of HTN in majority of cases in dialysis patients is excesses of total of body water (TBW) and excesses of total body Na (Removing th...

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RE: Mulytidrug resistant Nephrotic syndrome 3 days ago

Great comment. Gave you seen favorable responses ro Obi in patients with secondary (late) treatment unresponsive NS and FSGS lesions ? ----------...

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igan nephropathy 3 days ago

Good morning, I saw a 18 y/o Male who presented to hospital with chief complaint of gross hematuria and Acute kidney Injury (creatinine up to 2 ...

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RE: resistant hypertension in hemodialysis patient even after bilateral renal embolization 3 days ago

Has anyone studied the effects of renal denervation in a dialysis patient with resistant hypertension after bilateral renal embolization.? I cant f...

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RE: Mulytidrug resistant Nephrotic syndrome 3 days ago

We have had excellent response to IV Obinutuzumab. Recently presented our data at ASN meeting. ------------------------------ Isabel Roberti MD, ...

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RE: resistant hypertension in hemodialysis patient even after bilateral renal embolization 3 days ago

I had experience of one such patient where the BMI was low. All efforts to control hypertension failed Finally Bioimpedence suggested volume ove...

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RE: AKI with IGA Nephropathy 3 days ago

Wonder if gross hematuria and tubular obstruction by RBCs may beplaying a role (a la, warfarin nephropathy). Gross hematuria without warfarin/high ...

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RE: Podocyte Talk - weekly nephrology audio summary Monday, November 4 @ 4:21 AM

Thank you for this explanation. Good lick with your project. ------------------------------ Richard Glassock MD, FASN Laguna Woods CA (949) 388-8...

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