RE: Renal Artery Stenosis Case 1 hour ago

the CTA evaluated both kidneys? ------------------------------ Roger Rodby MD, FASN Professor of Medicine Rush University Medical Center Chicago...

View Discussion

CALL FOR CASE SUBMISSIONS ANNUAL DIALYSIS CONFERENCE (MARCH 2025). GRANTS AVAILABLE FOR SELECTED CASES! 1 hour ago

Dear all, We cordially invite you to submit a challenging or interesting dialysis case for presentation at our upcoming conference in Las Vegas,...

View Discussion

RE: Steroid resistance nephrotic syndrome 2 hours ago

I agree. It was a long shot anyway. But that genetics cannot be ignored. Especially the 'likely pathogenic' bit. Is there any family history of amy...

View Discussion

RE: Renal Artery Stenosis Case 2 hours ago

Was the hypertensive crisis due to NSAID use? If so there is no need to do anything else. Perhaps the knee replacement would help. If obese, semagl...

View Discussion

RE: Renal Artery Stenosis Case 3 hours ago

So she is now in her mid-60's? What has happened to kidney function over time, especially with increase in ACEi dose? Any reason for the HTN crisis...

View Discussion

RE: Apply today!! Travel Support Scholarship for Nephrology Fellows to attend Annual Dialysis Conference, Las Vegas 2025. 3 hours ago

Hello! I am doing first year nephrology fellowship and I am interested in any opportunity regarding nephrology especially home dialysis topic.I t...

View Discussion

RE: ATI, Anuria post kidney transplant 8 hours ago

My thought this is not recurrent FSGS and as there is no rejection so this is ATN and UTI I would worried about low TAC levels and uptitrate to tro...

View Discussion

RE: Steroid resistance nephrotic syndrome 15 hours ago

Thanks. No amyloid by EM. Biopsy consistent with a diffuse Podocytopathy .. ------------------------------ Richard Glassock MD, FASN Laguna Wood...

View Discussion

RE: Steroid resistance nephrotic syndrome 16 hours ago

I attached the EM report. ------------------------------ Sura Alsaffar MD Pediatric Nephrology Fellow SUNY Downstate Health Science Univers...

View Discussion

RE: Steroid resistance nephrotic syndrome 16 hours ago

The early course of SSNS and a multi-relapsing course would not be very compatible with an underlying renal hereditary Amyloidosis, but the genetic...

View Discussion

RE: NELL-1 positive membranous 17 hours ago

Your assumption is correct. The only way we know by stopping amphetamine if it is the culprit if that is not possible then use ritixumab or obi is ...

View Discussion

RE: NELL-1 positive membranous 17 hours ago

This assumption is correct Only way we will know by stopping the drugIf not possible ritixumab or obi should tried Sent from my iPhoneSpelling mist...

View Discussion

RE: Steroid resistance nephrotic syndrome 17 hours ago

If EM was done in this biopsy, it should have excluded Amyloidosis as a cause. Do you have an EM report? ------------------------------ Richard ...

View Discussion

RE: NELL-1 positive membranous 17 hours ago

I do not think that any connection between Amphetamine use and MN (of any subtype ) exists. Is this a correct assumption? -----------------------...

View Discussion

RE: ATI, Anuria post kidney transplant 17 hours ago

Dr. Amara: Thanks for the update. Encouraged by improving urine output of 500 to 600 ml/day. Can you please obtain UAlb/Cr ratio and UPr/Cr ratio o...

View Discussion

Renal Artery Stenosis Case 17 hours ago

I saw a lady who left artery renal stenosis in 1980 presented with resistant HTN. She was in her 20. She had a graft from saphenous vein to left re...

View Discussion

RE: Apply today!! Travel Support Scholarship for Nephrology Fellows to attend Annual Dialysis Conference, Las Vegas 2025. 18 hours ago

Hello dearI will be so, proud if I got this chance to attend the conference in Las Vegas 2025..iam from Iraq Arabic board certified in nephrology a...

View Discussion

RE: NELL-1 positive membranous 19 hours ago

I would look hard for a malignancy , hepatitis etc (see below) ask hard for supplements, skin creams. then when coming up negative which I assume y...

View Discussion

RE: NELL-1 positive membranous 20 hours ago

He is too young for some CA associated with NELL1 but not impossible, prostate CA comes to mind. Treating with anti-CD20 is the best option now. I ...

View Discussion

RE: ATI, Anuria post kidney transplant 20 hours ago

@K.K. Venkat @Mark Lerman Quick update Start to pass urine ~500 -600 ml/d Repeat UPCR 2.6 gm/gm (Attached) Repeat UA: Pus cells 5-8 RBcs 70...

View Discussion

RE: Steroid resistance nephrotic syndrome 21 hours ago

All but 3 appear relatively preserved and mildly enlarged with somewhat smooth thickening of the peripheral capillary walls and generally patent lu...

View Discussion

RE: preoperative nephrology evaluation 1 day ago

None that I know of. ------------------------------ Richard Glassock MD, FASN Laguna Woods CA (949) 388-8885 ------------------------------

View Discussion

RE: Steroid resistance nephrotic syndrome 1 day ago

For how long was the first course of steroids? Why was followed by MMF? Steroids can work to reduce proteinuria in non-immunological way by acting...

View Discussion

RE: NELL-1 positive membranous 1 day ago

reposting to see if any other additional suggestions or input to help with this case? ------------------------------ Jagmeet Dhingra MD, FASN Bea...

View Discussion

RE: Steroid resistance nephrotic syndrome 1 day ago

Thank you Dr. Balan. I posted the genetic test results. ------------------------------ Sura Alsaffar MD Pediatric Nephrology Fellow SUNY Downst...

View Discussion

RE: Steroid resistance nephrotic syndrome 1 day ago

Gene Condition(s) Inheritance Variant(s) Zygosity Classification -FGA Hereditary Renal Amyloidosis (AD), Congenital Fibrinogen Deficiency (AD/AR) ...

View Discussion

RE: Nephrotic Syndrome In A Young Lady 1 day ago

I do not think it will change decision about treatment if staining is negative or positive. This an antibody driven disease. Other antigen are bein...

View Discussion

RE: Steroid resistance nephrotic syndrome 1 day ago

With SSNS it is not likely that genetic testing will be informative . But it would be nice to know what kind of Amyloidosis gene was detected. -...

View Discussion

RE: Steroid resistance nephrotic syndrome 1 day ago

Can you post the genetics report? ------------------------------ Satish Balan MD DM DNB Senior Consultant Department of Nephrology Kerala Institu...

View Discussion

RE: Steroid resistance nephrotic syndrome 2 days ago

For Obi in children and SRNS see Chan Y, et al Ped Nephrol 2024; October 28. ------------------------------ Richard Glassock MD, FASN Laguna Wood...

View Discussion

RE: Steroid resistance nephrotic syndrome 2 days ago

Thank you Dr. Rodby. Actually patient is not responding to steroids anymore. And regarding to OBI is there any ongoing trial or study on childr...

View Discussion

RE: Steroid resistance nephrotic syndrome 2 days ago

The good news is that this is steroid responsive, I agree that a hip infection would be highly unusual with anti-CD 20 alone, and is more likely ...

View Discussion

RE: ATI, Anuria post kidney transplant 2 days ago

Would continue Plex until EM is available -would continue Tac at therapeutic levels , If EM does not not support FSGS then would try to switch to B...

View Discussion

RE: Steroid resistance nephrotic syndrome 2 days ago

Very little data in children But at the ASN Renal week a pilot study with Obinutuzumab is SRNS in Adults due to Primary FSGS was very encouraging. ...

View Discussion

RE: NELL-1 positive membranous 2 days ago

Looks like malignancy and systemic work up is normal You did think of sarcoid So drug related disease has to be considered As per your post you di...

View Discussion

RE: NELL-1 positive membranous 2 days ago

ANA has been negative. CRP pretty much normal. No joint symptoms. No hypercalcemia. No lymph nodes. Other serologies also mentioned in the post and...

View Discussion

RE: NELL-1 positive membranous 2 days ago

Have you done autoimmune work up --------------------------------- Bajinder Reen MD Etobicoke ON (905) 453-0821 ---------------------------------

View Discussion

RE: NELL-1 positive membranous 2 days ago

Could this be related to amphetamine related NELl1 --------------------------------- Bajinder Reen MD Etobicoke ON (905) 453-0821 --------------...

View Discussion

NELL-1 positive membranous 2 days ago

would appreciate help in this case 30 year old caucasian male, medical history of pre diabetes, ADHD on amphetamine, fatty liver and obesity with ...

View Discussion

RE: Steroid resistance nephrotic syndrome 2 days ago

Thank you Dr. Glassock for your reply. actually Rituximab caused serum sickness post the second dose of the medication. I might be wrong regard...

View Discussion

RE: Steroid resistance nephrotic syndrome 2 days ago

Frequently relapsing steroid sensitive NS with onset at age 2 years with evolution to a lesion of diffuse podocytopathy , FSGS and secondary steroi...

View Discussion

Steroid resistance nephrotic syndrome 2 days ago

I welcome any input regarding a case I saw in our clinic of 6 year old girl with Nephrotic syndrome which was diagnosed when she was 2 year old. p...

View Discussion

RE: Nephrotic Syndrome In A Young Lady 2 days ago

Young woman with MGN with both mesangial deposits and sub epi deposits? not full house But feels like a class 5 lupus I look forward to whe...

View Discussion

RE: Nephrotic Syndrome In A Young Lady 2 days ago

This case raises questions which have remained unanswered for decades. What is the mechanism for a rise in serum albumin concentration independent ...

View Discussion

RE: Nephrotic Syndrome In A Young Lady 2 days ago

Then , if nephrotic syndrome persists, RTX is indicated as therapy. ------------------------------ Richard Glassock MD, FASN Laguna Woods CA (...

View Discussion

RE: Nephrotic Syndrome In A Young Lady 2 days ago

Unfortunately, staining for NELL , EXT I & II are not available. --------------------------------- Peter Youssef, MSc., MRCP (UK), ESENeph Cairo, ...

View Discussion

RE: preoperative nephrology evaluation 2 days ago

I mean like we have for cardiac risk ------------------------------ Sadeem Ali MD Bridgeport WV (612) 865-9067 ------------------------------

View Discussion

RE: preoperative nephrology evaluation 2 days ago

This becomes more concern for chronic kidney disease, Predialysis patients and I always wonder if there is a risk score calculator Something like w...

View Discussion

preoperative nephrology evaluation 2 days ago

We are getting a nephrology consult for evaluation of 77 age patient with ESRD (He is on hemodialysis via AV fistula 3 days a week outpatient since...

View Discussion

RE: Nephrotic Syndrome In A Young Lady 2 days ago

I will go out on theoretical limb. Steroids initially drop lymphoyctic count and we see that after starting high therapy. Not sure they can deplete...

View Discussion