RE: ATI, Anuria post kidney transplant 8 minutes ago

As previously stated, as many as 20-24 PLEX treatments may be required before declaring failure in patients with recurrent FSGS. In responders, tap...

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RE: Hematuria in 14 years old 17 minutes ago

Agree with biopsy for the indication of nephrotic-range proteinuria > 40 mg/m2/hr (assuming BSA of ~1.5 m2). Adolescent IgA Vasculitis is different...

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RE: DR MISMATCH in Kidney Allocation 23 minutes ago

Agree with Dr. Balan. We look into HLA matching in first kidney transplant from a living donor only if more than one living donor is available. If ...

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RE: DR MISMATCH in Kidney Allocation 31 minutes ago

Agree with Dr Balan, a dialysis patient will be much better served with a transplant from a DR mismatched donor than staying on dialysis. Graft hal...

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RE: Anca vasculitis relapse without circulating antibodies 41 minutes ago

The original biopsy was pretty bad This may all be just scarring would you consider rebiopsy? ------------------------------ Roger Rodb...

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RE: Hematuria in 14 years old 46 minutes ago

I would biopsy, the question will be, would you treat this (I am assuming it will be IgAN) at age 14, with one of the newer agents, and if so whi...

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RE: DR MISMATCH in Kidney Allocation 50 minutes ago

Is the question with regard to the launch of a deceased donor program? If this were a live donor program I don't really see the point of looking fo...

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Anca vasculitis relapse without circulating antibodies 1 hour ago

Dear all, I would like to discuss the following case: 46-year-old male with a history of hypertension (since 2002), pre-diabetes, dyslipidemia, a...

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DR MISMATCH in Kidney Allocation 8 hours ago

Hi everyone I need your insight as regard the importance of DR mismatch in kidney allocation system, do we still be concerned about the presence of...

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RE: ATI, Anuria post kidney transplant 9 hours ago

Our patient is currently on plasma exchange with significant reduction in Proteinuria Last UACR 1300 mg Will measure UPCR and UACR simultaneousl...

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RE: Hematuria in 14 years old 11 hours ago

I would do a kidney biopsy. The likely diagnosis is IgA Vasculitis . ------------------------------ Richard Glassock MD, FASN Laguna Woods CA (9...

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Hematuria in 14 years old 12 hours ago

14 years old male patient ( with normal birth weight) free medical history presented with history of episode macroscopic Hematuria 2 months ag...

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RE: Measurement of Electrolytes 21 hours ago

Thanks ------------------------------ Brian Cronin MD, FASN Hypertension Nephrology Associates, P.C. Huntingdon Valley PA (215) 947-4533 --------...

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RE: Measurement of Electrolytes 21 hours ago

Hi, In my experience the difference (particularly in sodium) often is clinically important, this past week I observed a sodium of 123 on the bloo...

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RE: Measurement of Electrolytes 23 hours ago

If I ran the same specimen three times with the same machine I suspect we would see 3 different values. Are these differences we see between diff...

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RE: Measurement of Electrolytes 1 day ago

Perhaps this bias is simply the result of the 2 analytic platforms being poorly calibrated to each other. Assuming good calibration, a common cause...

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RE: Measurement of Electrolytes 1 day ago

I think we need both methods of measurement as BGAs are helpful in critical care setting for rapid decisions and treatment of life-threatening elec...

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RE: Measurement of Electrolytes 1 day ago

This phenomenon is well described - electrolyte values from blood gas specimens can be determined rapidly but caution should be used in interpretin...

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Measurement of Electrolytes 1 day ago

My anecdotal observation at the hospital I work is that the sodium runs lower and potassium higher on blood gas (whole blood) measurements than che...

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RE: Clinical Practice Questions 2 days ago

Dr. Venkat. Many thanks. Very clear answer. ------------------------------ Richard Glassock MD, FASN Laguna Woods CA (949) 388-8885 ------------...

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RE: Clinical Practice Questions 2 days ago

CMV interstitial nephritis is usually diagnosed by demonstration of characteristic CMV inclusions in tubular epithelial cells and/or interstitial i...

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RE: Clot/ Debris In Right Jugular Vein 2 days ago

Yes definitely looks like a clot. Anecdotally, from having placed and replaced many tunneled lines, I think this is fairly common and can be attrib...

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RE: Clinical Practice Questions 2 days ago

Dr. Venkat - given the findings in the transplant kidney biopsy by LM, (largely foci of tubulitis) do you believe that a DNA hybridization examinat...

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RE: ATI, Anuria post kidney transplant 2 days ago

Dr. Emara: Can you please provide another update on your patient? Did you check UPr/Cr and UAlb/Cr or urine protein electrophoresis? Further treatm...

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RE: Clinical Practice Questions 3 days ago

Biopsy shows ATN and IFTA. No evidence of antibody-mediated rejection. "Borderline TCMR" findings may be from ATN and chronic IFTA and may not be f...

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Florida society of nephrology annual meeting 3 days ago

https://www.floridasocietyofnephrology.com/page/Agenda2025 I am the president of this organization currently .Please take a look at the agenda an...

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RE: Encapsulating peritoneal sclerosis 3 days ago

Thanks for more information It looks like you may have caught this early on the scale of the natural history of EPS. But I would still be aggre...

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RE: Clot/ Debris In Right Jugular Vein 3 days ago

@Monnie Wasse ------------------------------ Roger Rodby MD, FASN Professor of Medicine Rush University Nephrology Associates Chicago IL (773) 50...

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RE: Clot/ Debris In Right Jugular Vein 3 days ago

Pleasure prof glassock Merry Christmas and happy new year to you and everyone on here Best wishes --------------------------------- Muhammad S...

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RE: Clot/ Debris In Right Jugular Vein 3 days ago

Thanks for the photo and folllw-up. ------------------------------ Richard Glassock MD, FASN Laguna Woods CA (949) 388-8885 ---------------------...

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RE: Clot/ Debris In Right Jugular Vein 3 days ago

photos attached finally . He had clot in left jugular vein. we did a tunnelled dialysis catheter on left side. we requested thrombophilia screen an...

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RE: Clinical Practice Questions 3 days ago

biopsy screenshots thanks ------------------------------ Muhammad Soobadar MBChB UK ------------------------------ Files Attached Do...

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RE: Encapsulating peritoneal sclerosis 3 days ago

thank you for your responses. the pt is a 50 yo man with diabetes, HTN, hyperlipidemia with ESRD. he was on PD for 2 years but had issues with no...

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RE: Encapsulating peritoneal sclerosis Thursday, December 19 @ 10:47 AM

EPS is like what Primary Systemic Amyloidosis was 2 decades ago. Look what happened. We may have to resort to desperate remedies of very uncertain ...

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RE: Encapsulating peritoneal sclerosis Thursday, December 19 @ 3:28 AM

How long was he on PD? How was this diagnosed and by what parameter is he improving? what prednisone dose are you considering? I would add a...

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RE: Encapsulating peritoneal sclerosis Wednesday, December 18 @ 9:03 PM

I have no idea how to answer your questions. Is any data available that would help? This is an area of known unknowns. --------------------------...

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RE: Curious about Anti Nephrin Antibody commercial availability Wednesday, December 18 @ 8:34 PM

Thank you for your email.It was helpful.RegardsKrishna

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RE: Question about Hepatitis B Isolation s/p Liver Transplant Wednesday, December 18 @ 7:17 PM

Dr. Rodby- you may be right about the perceptions of regulators. The point is that HBV infections are very very difficult to cure- if this is even ...

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RE: Curious about Anti Nephrin Antibody commercial availability Wednesday, December 18 @ 7:12 PM

Development of a (quantitative ) commercial assay for serum anti-Nephrin antibodies is going to be a lot more difficult than we experienced with an...

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RE: Curious about Anti Nephrin Antibody commercial availability Wednesday, December 18 @ 6:16 PM

I assume you meant blood? I believe that Dr Glassock is speaking only for tissue IF. And anti-nephrin Abs for MCD is not close to the utility ...

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RE: Question about Hepatitis B Isolation s/p Liver Transplant Wednesday, December 18 @ 5:56 PM

"With absence of DNA and if antiHbs is positive there is a very low chance of infection spread and it may be safe to dialyze in the main unit with ...

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RE: Question about Hepatitis B Isolation s/p Liver Transplant Wednesday, December 18 @ 3:49 PM

Excellent discussion. Thank you for all your help. I am checking a DNA PCR and awaiting those results before deciding on Isolation. I did consult w...

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RE: Question about Hepatitis B Isolation s/p Liver Transplant Wednesday, December 18 @ 1:36 PM

This patient had a hepatitis B infection in the past and has now lost the HBsAg status. This could be due to, as already pointed out, a precore mut...

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RE: Question about Hepatitis B Isolation s/p Liver Transplant Wednesday, December 18 @ 9:13 AM

Is your patient on prophylactic anti-HBV therapy? ------------------------------ Richard Glassock MD, FASN Laguna Woods CA (949) 388-8885 -------...

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RE: Question about Hepatitis B Isolation s/p Liver Transplant Wednesday, December 18 @ 9:08 AM

You may consider discussing the matter with the superb ID and hepatologists in the bay area. ------------------------------ Mario Rubin, M.D. Ho...

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RE: Question about Hepatitis B Isolation s/p Liver Transplant Wednesday, December 18 @ 8:54 AM

Thank you all for your comments. ------------------------------ David Pai MD, FASN Capital Nephrology Medical Group Sacramento CA (916) 647-7231...

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RE: Question about Hepatitis B Isolation s/p Liver Transplant Wednesday, December 18 @ 8:39 AM

suggest HbeAg, and HBeAb along with HBV DNA PCR. If he has high viral loads he should be on lifelong antivirals eg entecavir. The recommendations w...

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RE: Question about Hepatitis B Isolation s/p Liver Transplant Wednesday, December 18 @ 8:07 AM

IMO DNA and simultaneous serology should be performed ------------------------------ Arvind Madan MBBS, MD Partner Central Florida Kidney Spe...

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RE: Curious about Anti Nephrin Antibody commercial availability Wednesday, December 18 @ 1:11 AM

Commercial availability of anti-nephrin antibody tests will likely vary by country and by regulatory authority. It is not an easy assay to develop ...

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Curious about Anti Nephrin Antibody commercial availability Tuesday, December 17 @ 11:16 PM

Hi, I am curious about what could be the time line for commercial availability of the Anti Nephrin antibody level detection by ELISA for use in C...

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