ASN's Mission

To create a world without kidney diseases, the ASN Alliance for Kidney Health elevates care by educating and informing, driving breakthroughs and innovation, and advocating for policies that create transformative changes in kidney medicine throughout the world.

learn more

Contact ASN

1401 H St, NW, Ste 900, Washington, DC 20005

email@asn-online.org

202-640-4660

The Latest on X

Kidney Week

Please note that you are viewing an archived section from 2023 and some content may be unavailable. To unlock all content for 2023, please visit the archives.

Abstract: FR-PO857

Adverse Maternal-Fetal Outcomes in Pregnant Women with CKD on Hemodialysis: A Single-Center Experience

Session Information

Category: Women's Health and Kidney Diseases

  • 2200 Women's Health and Kidney Diseases

Authors

  • Andrade-Sierra, Jorge, Universidad de Guadalajara Centro Universitario de Ciencias de la Salud, Guadalajara, Jalisco, Mexico
  • Bautista Melo, Berenice, Instituto Mexicano del Seguro Social Delegacion Jalisco, Guadalajara, Jalisco, Mexico
  • Carvallo Venegas, Mauricio, Instituto Mexicano del Seguro Social Delegacion Jalisco, Guadalajara, Jalisco, Mexico
  • Banda Lopez, Adriana, Instituto Mexicano del Seguro Social Delegacion Jalisco, Guadalajara, Jalisco, Mexico
  • Mendoza Cabrera, Salvador, Instituto Mexicano del Seguro Social Delegacion Jalisco, Guadalajara, Jalisco, Mexico
  • Parra Guerra, Ricardo, Instituto Mexicano del Seguro Social Delegacion Jalisco, Guadalajara, Jalisco, Mexico
  • Moreno De los Rios, María del Rosario, Instituto Mexicano del Seguro Social Delegacion Jalisco, Guadalajara, Jalisco, Mexico
  • Cerrillos, Jose Ignacio, Instituto Mexicano del Seguro Social Delegacion Jalisco, Guadalajara, Jalisco, Mexico
  • Evangelista-Carrillo, Luis Alberto, Instituto Mexicano del Seguro Social Delegacion Jalisco, Guadalajara, Jalisco, Mexico
  • Medina Perez, Miguel, Instituto Mexicano del Seguro Social Delegacion Jalisco, Guadalajara, Jalisco, Mexico
Background

Chronic kidney disease (CKD) pregnant women are at high risk of adverse maternal and fetal outcomes (AMAFO). 4% of women of childbearing age suffer from CKD, an independent risk factor for prematurity, low birth weight, neonatal death, and preeclampsia. Objective: To determine the incidence of AMAFO in pregnant women with CKD in hemodialysis (HD).

Methods

Observational retrospective study of 30 patients with CKD in HD and pregnancy from Aug 2017 to Dec 2021. Sociodemographic data, comorbidities, and AMAFO were recorded and analyzed.

Results

The incidence of adverse maternal events was 33%, the most frequent was preeclampsia with severe features (17%), followed by preeclampsia (7 %), HELLP syndrome (3%), gestational diabetes (3%), and placental abruption (3%). Neither patient died during the follow-up. 90% of the newborns present with adverse fetal outcomes, 90% with low birth weight, 40% with prematurity, 13 % with transient tachypnea of the newborn, 7% with premature rupture of the membranes, 7% with fetal distress, and 17% died.

Conclusion

There was a 33% incidence of adverse maternal events and 90% of adverse fetal outcomes in pregnant women with CKD in HD, with only 10% of pregnancies without AMAFO.

 N= 30
Age (years)28.87 ± 4.1
Preeclampsia in previous pregnancies n (%) 6 (20%)
Chronic hypertension n (%)23 (77%)
Diabetes n (%)3 (10%)
CKD diagnosis before pregnancy n (%)25 (83%)
GFR n (ml/min/1.73m2)18.127; 5.7-55.8
24-hour urinary creatine clearance (ml/min/1.73m2) 14.1954 ± 7.2
Start of hemodialysis  
First trimester5 (17%)
Second trimester17 (57%)
Third trimester8 (26%)