Abstract: FR-PO857
Adverse Maternal-Fetal Outcomes in Pregnant Women with CKD on Hemodialysis: A Single-Center Experience
Session Information
- Women's Health and Kidney Diseases
November 03, 2023 | Location: Exhibit Hall, Pennsylvania Convention Center
Abstract Time: 10:00 AM - 12:00 PM
Category: Women's Health and Kidney Diseases
- 2200 Women's Health and Kidney Diseases
Authors
- Andrade-Sierra, Jorge, Universidad de Guadalajara Centro Universitario de Ciencias de la Salud, Guadalajara, Jalisco, Mexico
- Bautista Melo, Berenice, Instituto Mexicano del Seguro Social Delegacion Jalisco, Guadalajara, Jalisco, Mexico
- Carvallo Venegas, Mauricio, Instituto Mexicano del Seguro Social Delegacion Jalisco, Guadalajara, Jalisco, Mexico
- Banda Lopez, Adriana, Instituto Mexicano del Seguro Social Delegacion Jalisco, Guadalajara, Jalisco, Mexico
- Mendoza Cabrera, Salvador, Instituto Mexicano del Seguro Social Delegacion Jalisco, Guadalajara, Jalisco, Mexico
- Parra Guerra, Ricardo, Instituto Mexicano del Seguro Social Delegacion Jalisco, Guadalajara, Jalisco, Mexico
- Moreno De los Rios, María del Rosario, Instituto Mexicano del Seguro Social Delegacion Jalisco, Guadalajara, Jalisco, Mexico
- Cerrillos, Jose Ignacio, Instituto Mexicano del Seguro Social Delegacion Jalisco, Guadalajara, Jalisco, Mexico
- Evangelista-Carrillo, Luis Alberto, Instituto Mexicano del Seguro Social Delegacion Jalisco, Guadalajara, Jalisco, Mexico
- Medina Perez, Miguel, Instituto Mexicano del Seguro Social Delegacion Jalisco, Guadalajara, Jalisco, Mexico
Background
Chronic kidney disease (CKD) pregnant women are at high risk of adverse maternal and fetal outcomes (AMAFO). 4% of women of childbearing age suffer from CKD, an independent risk factor for prematurity, low birth weight, neonatal death, and preeclampsia. Objective: To determine the incidence of AMAFO in pregnant women with CKD in hemodialysis (HD).
Methods
Observational retrospective study of 30 patients with CKD in HD and pregnancy from Aug 2017 to Dec 2021. Sociodemographic data, comorbidities, and AMAFO were recorded and analyzed.
Results
The incidence of adverse maternal events was 33%, the most frequent was preeclampsia with severe features (17%), followed by preeclampsia (7 %), HELLP syndrome (3%), gestational diabetes (3%), and placental abruption (3%). Neither patient died during the follow-up. 90% of the newborns present with adverse fetal outcomes, 90% with low birth weight, 40% with prematurity, 13 % with transient tachypnea of the newborn, 7% with premature rupture of the membranes, 7% with fetal distress, and 17% died.
Conclusion
There was a 33% incidence of adverse maternal events and 90% of adverse fetal outcomes in pregnant women with CKD in HD, with only 10% of pregnancies without AMAFO.
N= 30 | |
Age (years) | 28.87 ± 4.1 |
Preeclampsia in previous pregnancies n (%) | 6 (20%) |
Chronic hypertension n (%) | 23 (77%) |
Diabetes n (%) | 3 (10%) |
CKD diagnosis before pregnancy n (%) | 25 (83%) |
GFR n (ml/min/1.73m2) | 18.127; 5.7-55.8 |
24-hour urinary creatine clearance (ml/min/1.73m2) | 14.1954 ± 7.2 |
Start of hemodialysis | |
First trimester | 5 (17%) |
Second trimester | 17 (57%) |
Third trimester | 8 (26%) |